JPS6438029A - Soluble and powdery preparation of cyclosporin - Google Patents
Soluble and powdery preparation of cyclosporinInfo
- Publication number
- JPS6438029A JPS6438029A JP62193129A JP19312987A JPS6438029A JP S6438029 A JPS6438029 A JP S6438029A JP 62193129 A JP62193129 A JP 62193129A JP 19312987 A JP19312987 A JP 19312987A JP S6438029 A JPS6438029 A JP S6438029A
- Authority
- JP
- Japan
- Prior art keywords
- organic solvent
- preparation
- solid
- powdered
- solvent soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PURPOSE:To obtain the titled powdery preparation made powdering of cyclosporins supplied in a form of oil preparation possible, by using an organic solvent soluble surfactant each medically permissible and organic solvent soluble substance which is solid at ordinary temperature. CONSTITUTION:(A) At least one kind of cyclosporins such as cyclosporin A useful as an immunosuppressive agent, (B) organic solvent soluble surfactant medically permissible and (C) organic solvent soluble substance medically permissible and solid at ordinary temperature are dissolved in an organic solvent and then the solvent is evaporated and the residual solid is powdered or the component C is heated and melted and the solvent is evaporated and the remaining solid is powdered or component C is heated and melted and components A and B are dissolved thereto and the solution is cooled and solidified and then powdered to provide the powdery preparation for the above- mentioned medicine consisting of powder of dense blend of three components and capable of supplying the above-mentioned medicine fed at form of oily preparation remarkably inconvenient in storage, transportation and usage at form of the powdery preparation.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62193129A JP2536876B2 (en) | 1987-07-31 | 1987-07-31 | Dissolvable powder formulation of cyclosporine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62193129A JP2536876B2 (en) | 1987-07-31 | 1987-07-31 | Dissolvable powder formulation of cyclosporine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6438029A true JPS6438029A (en) | 1989-02-08 |
JP2536876B2 JP2536876B2 (en) | 1996-09-25 |
Family
ID=16302750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62193129A Expired - Lifetime JP2536876B2 (en) | 1987-07-31 | 1987-07-31 | Dissolvable powder formulation of cyclosporine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2536876B2 (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2230440A (en) * | 1989-02-09 | 1990-10-24 | Sandoz Ltd | Cyclosporin compositions |
WO1995022982A1 (en) * | 1994-02-25 | 1995-08-31 | Chong Kun Dang Corp. | Cyclosporin-containing powder composition |
FR2722984A1 (en) * | 1994-07-26 | 1996-02-02 | Effik Laboratoires | Solid drug dispersion in cyclic amide carrier, pref. PVP |
US5756450A (en) * | 1987-09-15 | 1998-05-26 | Novartis Corporation | Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms |
JPH10512447A (en) * | 1995-01-20 | 1998-12-02 | ユニバーシティ オブ マサチューセッツ メディカルセンター | Nonsense-mediated production of heterologous polypeptides in the absence of mRNA decay function |
JP2002140168A (en) * | 2000-10-31 | 2002-05-17 | Sony Corp | Data conversion device, storage device, protocol conversion device, device control unit, recording and reproducing system, recording and reproducing method, and management method of storage capacity |
JP2010519228A (en) * | 2007-02-22 | 2010-06-03 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | Active substance-pellets having a matrix and a polymer coating and method for producing the pellets |
JP2015086155A (en) * | 2013-10-29 | 2015-05-07 | リンテック株式会社 | Method for releasing functional material, kit for releasing functional material, and releasing composition |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4521554B2 (en) * | 2004-03-31 | 2010-08-11 | マイラン製薬株式会社 | Cyclosporine preparation |
-
1987
- 1987-07-31 JP JP62193129A patent/JP2536876B2/en not_active Expired - Lifetime
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5756450A (en) * | 1987-09-15 | 1998-05-26 | Novartis Corporation | Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms |
GB2230440A (en) * | 1989-02-09 | 1990-10-24 | Sandoz Ltd | Cyclosporin compositions |
AT404552B (en) * | 1989-02-09 | 1998-12-28 | Novartis Erfind Verwalt Gmbh | NEW GALENIC FORMULATIONS CONTAINING CYCLOSPORINE |
WO1995022982A1 (en) * | 1994-02-25 | 1995-08-31 | Chong Kun Dang Corp. | Cyclosporin-containing powder composition |
US5543393A (en) * | 1994-02-25 | 1996-08-06 | Chong Kun Dang Corp. | Cyclosporin containing powder composition |
FR2722984A1 (en) * | 1994-07-26 | 1996-02-02 | Effik Laboratoires | Solid drug dispersion in cyclic amide carrier, pref. PVP |
WO1997004749A1 (en) * | 1994-07-26 | 1997-02-13 | Laboratoires Effik | Method for preparing dry pharmaceutical forms, and resulting pharmaceutical compositions |
EP0761208A1 (en) * | 1994-07-26 | 1997-03-12 | Laboratoires EFFIK | Process for preparing dry pharmaceutical forms and compositions thus made |
JPH10512447A (en) * | 1995-01-20 | 1998-12-02 | ユニバーシティ オブ マサチューセッツ メディカルセンター | Nonsense-mediated production of heterologous polypeptides in the absence of mRNA decay function |
JP2002140168A (en) * | 2000-10-31 | 2002-05-17 | Sony Corp | Data conversion device, storage device, protocol conversion device, device control unit, recording and reproducing system, recording and reproducing method, and management method of storage capacity |
JP2010519228A (en) * | 2007-02-22 | 2010-06-03 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | Active substance-pellets having a matrix and a polymer coating and method for producing the pellets |
JP2015086155A (en) * | 2013-10-29 | 2015-05-07 | リンテック株式会社 | Method for releasing functional material, kit for releasing functional material, and releasing composition |
Also Published As
Publication number | Publication date |
---|---|
JP2536876B2 (en) | 1996-09-25 |
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