JPS6438029A - Soluble and powdery preparation of cyclosporin - Google Patents

Soluble and powdery preparation of cyclosporin

Info

Publication number
JPS6438029A
JPS6438029A JP62193129A JP19312987A JPS6438029A JP S6438029 A JPS6438029 A JP S6438029A JP 62193129 A JP62193129 A JP 62193129A JP 19312987 A JP19312987 A JP 19312987A JP S6438029 A JPS6438029 A JP S6438029A
Authority
JP
Japan
Prior art keywords
organic solvent
preparation
solid
powdered
solvent soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62193129A
Other languages
Japanese (ja)
Other versions
JP2536876B2 (en
Inventor
Kanji Takada
Shozo Muranishi
Hiroyuki Yoshikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP62193129A priority Critical patent/JP2536876B2/en
Publication of JPS6438029A publication Critical patent/JPS6438029A/en
Application granted granted Critical
Publication of JP2536876B2 publication Critical patent/JP2536876B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PURPOSE:To obtain the titled powdery preparation made powdering of cyclosporins supplied in a form of oil preparation possible, by using an organic solvent soluble surfactant each medically permissible and organic solvent soluble substance which is solid at ordinary temperature. CONSTITUTION:(A) At least one kind of cyclosporins such as cyclosporin A useful as an immunosuppressive agent, (B) organic solvent soluble surfactant medically permissible and (C) organic solvent soluble substance medically permissible and solid at ordinary temperature are dissolved in an organic solvent and then the solvent is evaporated and the residual solid is powdered or the component C is heated and melted and the solvent is evaporated and the remaining solid is powdered or component C is heated and melted and components A and B are dissolved thereto and the solution is cooled and solidified and then powdered to provide the powdery preparation for the above- mentioned medicine consisting of powder of dense blend of three components and capable of supplying the above-mentioned medicine fed at form of oily preparation remarkably inconvenient in storage, transportation and usage at form of the powdery preparation.
JP62193129A 1987-07-31 1987-07-31 Dissolvable powder formulation of cyclosporine Expired - Lifetime JP2536876B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62193129A JP2536876B2 (en) 1987-07-31 1987-07-31 Dissolvable powder formulation of cyclosporine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62193129A JP2536876B2 (en) 1987-07-31 1987-07-31 Dissolvable powder formulation of cyclosporine

Publications (2)

Publication Number Publication Date
JPS6438029A true JPS6438029A (en) 1989-02-08
JP2536876B2 JP2536876B2 (en) 1996-09-25

Family

ID=16302750

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62193129A Expired - Lifetime JP2536876B2 (en) 1987-07-31 1987-07-31 Dissolvable powder formulation of cyclosporine

Country Status (1)

Country Link
JP (1) JP2536876B2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2230440A (en) * 1989-02-09 1990-10-24 Sandoz Ltd Cyclosporin compositions
WO1995022982A1 (en) * 1994-02-25 1995-08-31 Chong Kun Dang Corp. Cyclosporin-containing powder composition
FR2722984A1 (en) * 1994-07-26 1996-02-02 Effik Laboratoires Solid drug dispersion in cyclic amide carrier, pref. PVP
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
JPH10512447A (en) * 1995-01-20 1998-12-02 ユニバーシティ オブ マサチューセッツ メディカルセンター Nonsense-mediated production of heterologous polypeptides in the absence of mRNA decay function
JP2002140168A (en) * 2000-10-31 2002-05-17 Sony Corp Data conversion device, storage device, protocol conversion device, device control unit, recording and reproducing system, recording and reproducing method, and management method of storage capacity
JP2010519228A (en) * 2007-02-22 2010-06-03 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング Active substance-pellets having a matrix and a polymer coating and method for producing the pellets
JP2015086155A (en) * 2013-10-29 2015-05-07 リンテック株式会社 Method for releasing functional material, kit for releasing functional material, and releasing composition

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4521554B2 (en) * 2004-03-31 2010-08-11 マイラン製薬株式会社 Cyclosporine preparation

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
GB2230440A (en) * 1989-02-09 1990-10-24 Sandoz Ltd Cyclosporin compositions
AT404552B (en) * 1989-02-09 1998-12-28 Novartis Erfind Verwalt Gmbh NEW GALENIC FORMULATIONS CONTAINING CYCLOSPORINE
WO1995022982A1 (en) * 1994-02-25 1995-08-31 Chong Kun Dang Corp. Cyclosporin-containing powder composition
US5543393A (en) * 1994-02-25 1996-08-06 Chong Kun Dang Corp. Cyclosporin containing powder composition
FR2722984A1 (en) * 1994-07-26 1996-02-02 Effik Laboratoires Solid drug dispersion in cyclic amide carrier, pref. PVP
WO1997004749A1 (en) * 1994-07-26 1997-02-13 Laboratoires Effik Method for preparing dry pharmaceutical forms, and resulting pharmaceutical compositions
EP0761208A1 (en) * 1994-07-26 1997-03-12 Laboratoires EFFIK Process for preparing dry pharmaceutical forms and compositions thus made
JPH10512447A (en) * 1995-01-20 1998-12-02 ユニバーシティ オブ マサチューセッツ メディカルセンター Nonsense-mediated production of heterologous polypeptides in the absence of mRNA decay function
JP2002140168A (en) * 2000-10-31 2002-05-17 Sony Corp Data conversion device, storage device, protocol conversion device, device control unit, recording and reproducing system, recording and reproducing method, and management method of storage capacity
JP2010519228A (en) * 2007-02-22 2010-06-03 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング Active substance-pellets having a matrix and a polymer coating and method for producing the pellets
JP2015086155A (en) * 2013-10-29 2015-05-07 リンテック株式会社 Method for releasing functional material, kit for releasing functional material, and releasing composition

Also Published As

Publication number Publication date
JP2536876B2 (en) 1996-09-25

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