JPS643122A - Remedy for endometriosis - Google Patents
Remedy for endometriosisInfo
- Publication number
- JPS643122A JPS643122A JP15803087A JP15803087A JPS643122A JP S643122 A JPS643122 A JP S643122A JP 15803087 A JP15803087 A JP 15803087A JP 15803087 A JP15803087 A JP 15803087A JP S643122 A JPS643122 A JP S643122A
- Authority
- JP
- Japan
- Prior art keywords
- endometriosis
- gonatriene
- alkyl
- active ingredient
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
PURPOSE: To obtain a remedy for endometriosis useful for treating endometriosis, suppressing production and release of pituitary gonadotropin, containing a gonatriene derivative as an active ingredient.
CONSTITUTION: A gonatriene derivative shown by the formula (R is 1W3C alkyl; X is -OR1 or -SR2; R1 and R2 are 1W3C alkyl) as an active ingredient is pharmaceutically manufactured by a conventional procedure to give the aimed substance. The substance can be prepared into powder, granule, tablet, capsule, solution, suppository, emulsion or injection and a dose is about 0.1W50mg per adult daily in the case of oral administration. The compound shown by the formula is obtained by deriving an alkoxymethyltriene from a diketone, decomposing acetal group under an acidic condition to regenerate carbonyl group at the 3-position and 17α-methoxymethyl-17β-hydroxy-13β-methyl- gona-4,9,11-trien-3-one may be cited as the compound.
COPYRIGHT: (C)1989,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62-158030A JPH013122A (en) | 1987-06-25 | Endometriosis treatment drug |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62-158030A JPH013122A (en) | 1987-06-25 | Endometriosis treatment drug |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS643122A true JPS643122A (en) | 1989-01-06 |
JPH013122A JPH013122A (en) | 1989-01-06 |
Family
ID=
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5652231A (en) * | 1993-11-19 | 1997-07-29 | Mochida Pharmaceutical Co., Ltd. | Carcinostatic for hormonotherapy containing dienogest as effective component |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5652231A (en) * | 1993-11-19 | 1997-07-29 | Mochida Pharmaceutical Co., Ltd. | Carcinostatic for hormonotherapy containing dienogest as effective component |
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