JPS6426605A - Resin used in obtaining purified growth factor by affinity chromatography - Google Patents
Resin used in obtaining purified growth factor by affinity chromatographyInfo
- Publication number
- JPS6426605A JPS6426605A JP63093301A JP9330188A JPS6426605A JP S6426605 A JPS6426605 A JP S6426605A JP 63093301 A JP63093301 A JP 63093301A JP 9330188 A JP9330188 A JP 9330188A JP S6426605 A JPS6426605 A JP S6426605A
- Authority
- JP
- Japan
- Prior art keywords
- affinity chromatography
- growth factor
- groups
- resin used
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003102 growth factor Substances 0.000 title abstract 4
- 238000001042 affinity chromatography Methods 0.000 title abstract 3
- 239000011347 resin Substances 0.000 title abstract 2
- 229920005989 resin Polymers 0.000 title abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 108090000386 Fibroblast Growth Factor 1 Proteins 0.000 abstract 1
- 102100031706 Fibroblast growth factor 1 Human genes 0.000 abstract 1
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 abstract 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 abstract 1
- 230000005526 G1 to G0 transition Effects 0.000 abstract 1
- 229910006069 SO3H Inorganic materials 0.000 abstract 1
- 150000001412 amines Chemical group 0.000 abstract 1
- 150000003862 amino acid derivatives Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8705546A FR2613936B1 (fr) | 1987-04-17 | 1987-04-17 | Application des resines constituees par des polymeres fonctionnels comme phase stationnaire en chromatographie d'affinite pour la purification des facteurs de croissance et procede de purification correspondant |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6426605A true JPS6426605A (en) | 1989-01-27 |
Family
ID=9350280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63093301A Pending JPS6426605A (en) | 1987-04-17 | 1988-04-15 | Resin used in obtaining purified growth factor by affinity chromatography |
Country Status (7)
Country | Link |
---|---|
US (1) | US5122597A (ja) |
EP (1) | EP0287470B1 (ja) |
JP (1) | JPS6426605A (ja) |
AT (1) | ATE85892T1 (ja) |
DE (1) | DE3878577T2 (ja) |
ES (1) | ES2038320T3 (ja) |
FR (1) | FR2613936B1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012050386A (ja) * | 2010-09-01 | 2012-03-15 | Kaneka Corp | 2種類以上の多孔質充填剤を充填するカラム |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5120715A (en) * | 1988-12-12 | 1992-06-09 | Takeda Chemical Industries, Ltd. | Method for purifying fibroblast growth factor protein |
US5136025A (en) * | 1990-04-04 | 1992-08-04 | California Biotechnology Inc. | Method to purify basic fibroblast growth factor |
US20050096274A1 (en) * | 1998-04-07 | 2005-05-05 | Lough John W. | Bone morphogenetic protein and fibroblast growth factor compositions and methods for the induction of cardiogenesis |
US7022683B1 (en) * | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
US6313103B1 (en) | 1998-05-13 | 2001-11-06 | Carrington Laboratories, Inc. | Pectic substance as a growth factor stabilizer |
US5929051A (en) * | 1998-05-13 | 1999-07-27 | Carrington Laboratories, Inc. | Aloe pectins |
US7494669B2 (en) | 2001-02-28 | 2009-02-24 | Carrington Laboratories, Inc. | Delivery of physiological agents with in-situ gels comprising anionic polysaccharides |
SG11201406115VA (en) | 2012-03-30 | 2014-11-27 | Ajinomoto Kk | Culture medium for proliferating stem cell, which contains sulfated compound |
WO2016201348A1 (en) | 2015-06-10 | 2016-12-15 | Reflexion Medical, Inc. | High bandwidth binary multi-leaf collimator design |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2461724A1 (fr) * | 1979-07-20 | 1981-02-06 | Christine Fougnot | Polymeres substitues par des groupes leur conferant des proprietes anti-coagulantes et leur procede de preparation, objets constitues par et/ou comprenant lesdits polymeres et leurs procedes de fabrication, application desdits objets en chirurgie et en medecine, et compositions pharmaceutiques contenant lesdits polymeres substitues |
US4444760A (en) * | 1983-06-17 | 1984-04-24 | Merck & Co., Inc. | Purification and characterization of a protein fibroblast growth factor |
US4785079A (en) * | 1984-11-09 | 1988-11-15 | The Salk Institute For Biological Studies | Isolation of fibroblast growth factor |
FR2573997B1 (fr) * | 1984-12-03 | 1986-12-26 | Commissariat Energie Atomique | Support solide capable d'adsorber des lipoproteines et son utilisation pour la separation des lipoproteines de basse densite presentes dans un liquide tel que le plasma sanguin |
FR2586359B1 (fr) * | 1985-08-23 | 1989-09-08 | Commissariat Energie Atomique | Support solide a base d'alcool polyvinylique capable d'adsorber les lipoproteines et son utilisation pour la separation des lipoproteines de basse densite presentes dans un liquide tel que du plasma sanguin |
-
1987
- 1987-04-17 FR FR8705546A patent/FR2613936B1/fr not_active Expired - Fee Related
-
1988
- 1988-04-14 ES ES198888400909T patent/ES2038320T3/es not_active Expired - Lifetime
- 1988-04-14 EP EP88400909A patent/EP0287470B1/fr not_active Expired - Lifetime
- 1988-04-14 AT AT88400909T patent/ATE85892T1/de not_active IP Right Cessation
- 1988-04-14 DE DE8888400909T patent/DE3878577T2/de not_active Expired - Fee Related
- 1988-04-15 JP JP63093301A patent/JPS6426605A/ja active Pending
- 1988-04-15 US US07/182,191 patent/US5122597A/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012050386A (ja) * | 2010-09-01 | 2012-03-15 | Kaneka Corp | 2種類以上の多孔質充填剤を充填するカラム |
Also Published As
Publication number | Publication date |
---|---|
ATE85892T1 (de) | 1993-03-15 |
EP0287470A1 (fr) | 1988-10-19 |
FR2613936B1 (fr) | 1990-03-30 |
DE3878577T2 (de) | 1993-07-01 |
ES2038320T3 (es) | 1993-07-16 |
DE3878577D1 (de) | 1993-04-01 |
US5122597A (en) | 1992-06-16 |
EP0287470B1 (fr) | 1993-02-24 |
FR2613936A1 (fr) | 1988-10-21 |
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