JPS642584A - Dna and plasmid, and microorganism containing the same - Google Patents
Dna and plasmid, and microorganism containing the sameInfo
- Publication number
- JPS642584A JPS642584A JP63002647A JP264788A JPS642584A JP S642584 A JPS642584 A JP S642584A JP 63002647 A JP63002647 A JP 63002647A JP 264788 A JP264788 A JP 264788A JP S642584 A JPS642584 A JP S642584A
- Authority
- JP
- Japan
- Prior art keywords
- cdna
- clone
- simian
- culturing
- proinsulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013612 plasmid Substances 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title 1
- 239000002299 complementary DNA Substances 0.000 abstract 4
- 238000012258 culturing Methods 0.000 abstract 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 4
- 108010076181 Proinsulin Proteins 0.000 abstract 3
- 102000004877 Insulin Human genes 0.000 abstract 2
- 108090001061 Insulin Proteins 0.000 abstract 2
- 229940125396 insulin Drugs 0.000 abstract 2
- 210000000496 pancreas Anatomy 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241001646716 Escherichia coli K-12 Species 0.000 abstract 1
- 101000976075 Homo sapiens Insulin Proteins 0.000 abstract 1
- 102100034343 Integrase Human genes 0.000 abstract 1
- 241000282567 Macaca fascicularis Species 0.000 abstract 1
- 241000282560 Macaca mulatta Species 0.000 abstract 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 1
- 125000000086 dCMP group Chemical group 0.000 abstract 1
- 125000003791 dGMP group Chemical group 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 abstract 1
- 108091008146 restriction endonucleases Proteins 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803001928 DE3001928A1 (de) | 1980-01-19 | 1980-01-19 | Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus |
| DE3001928.4 | 1980-01-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP524081A Division JPS56104897A (en) | 1980-01-19 | 1981-01-19 | Polypeptide genetic manufacture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS642584A true JPS642584A (en) | 1989-01-06 |
| JPH012584A JPH012584A (ja) | 1989-01-06 |
Family
ID=
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4964590A (en) * | 1981-11-11 | 1990-10-23 | Shimano Industrial Company Limited | Fishing reel |
Non-Patent Citations (2)
| Title |
|---|
| BIOPHYS.J.=1979 * |
| PROC.NATI.ACAD.SCI.=1978US * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4964590A (en) * | 1981-11-11 | 1990-10-23 | Shimano Industrial Company Limited | Fishing reel |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2067574A (en) | 1981-07-30 |
| AU6628081A (en) | 1981-07-30 |
| ZA81292B (en) | 1982-02-24 |
| ES499053A0 (es) | 1982-02-16 |
| ATE5151T1 (de) | 1983-11-15 |
| IT8119180A0 (it) | 1981-01-16 |
| BE887129A (fr) | 1981-07-20 |
| SE8100241L (sv) | 1981-07-20 |
| DE3161251D1 (en) | 1984-01-19 |
| EP0032675B1 (de) | 1983-10-26 |
| AU545665B2 (en) | 1985-07-25 |
| NL8100210A (nl) | 1981-08-17 |
| CA1192153A (en) | 1985-08-20 |
| DE3001928A1 (de) | 1981-08-06 |
| GB2067574B (en) | 1983-10-19 |
| EP0032675A2 (de) | 1981-07-29 |
| ES8205427A1 (es) | 1982-06-01 |
| ES8203101A1 (es) | 1982-02-16 |
| FR2479851A1 (fr) | 1981-10-09 |
| JPS56104897A (en) | 1981-08-20 |
| EP0032675A3 (en) | 1981-11-11 |
| ES498451A0 (es) | 1981-11-01 |
| ES8200722A1 (es) | 1981-11-01 |
| IT1136557B (it) | 1986-09-03 |
| ES499054A0 (es) | 1982-06-01 |
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