WO1988000836A3 - Immunosuppresseur et son procede de fabrication - Google Patents

Immunosuppresseur et son procede de fabrication Download PDF

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Publication number
WO1988000836A3
WO1988000836A3 PCT/DE1987/000339 DE8700339W WO8800836A3 WO 1988000836 A3 WO1988000836 A3 WO 1988000836A3 DE 8700339 W DE8700339 W DE 8700339W WO 8800836 A3 WO8800836 A3 WO 8800836A3
Authority
WO
WIPO (PCT)
Prior art keywords
immuno
suppressor
manufacture
serum
immunisation
Prior art date
Application number
PCT/DE1987/000339
Other languages
German (de)
English (en)
Other versions
WO1988000836A2 (fr
Inventor
Peter Terness
Gerhard Opelz
Original Assignee
Fresenius Ag
Peter Terness
Gerhard Opelz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Ag, Peter Terness, Gerhard Opelz filed Critical Fresenius Ag
Publication of WO1988000836A2 publication Critical patent/WO1988000836A2/fr
Publication of WO1988000836A3 publication Critical patent/WO1988000836A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Sont décrits un immunosuppresseur sous forme d'un sérum immunosuppresseur et/ou d'une IS-IgG extraite de ce sérum, produit par immunisation d'un animal avec des cellules recouvertes d'anticorps, le procédé pour fabriquer ledit immunosuppresseur, et son utilisation pour supprimer la réponse immune humorale et/ou cellulaire.
PCT/DE1987/000339 1986-08-01 1987-08-01 Immunosuppresseur et son procede de fabrication WO1988000836A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863626110 DE3626110A1 (de) 1986-08-01 1986-08-01 Immunsuppressives serum
DEP3626110.6 1986-08-01

Publications (2)

Publication Number Publication Date
WO1988000836A2 WO1988000836A2 (fr) 1988-02-11
WO1988000836A3 true WO1988000836A3 (fr) 1988-02-25

Family

ID=6306509

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1987/000339 WO1988000836A2 (fr) 1986-08-01 1987-08-01 Immunosuppresseur et son procede de fabrication

Country Status (5)

Country Link
US (1) US5004604A (fr)
EP (1) EP0277160A1 (fr)
JP (1) JPH01500902A (fr)
DE (1) DE3626110A1 (fr)
WO (1) WO1988000836A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5230887A (en) * 1990-07-11 1993-07-27 Immune Network Research Ltd. Immune system stabilizers for prevention and therapy of disorders associated with immune system disfunction
US5292513A (en) * 1992-05-18 1994-03-08 Anthony G. Gristina Method for nonspecific cellular immune stimulation
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
EP1351697B1 (fr) * 2001-01-18 2013-10-30 Georg Watzek Agent pharmaceutique destine a favoriser la regeneration des tissus
GB0218613D0 (en) * 2002-08-10 2002-09-18 Lucite Int Uk Ltd Process for the carbonylation of ethylenically unsaturated compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728614A (en) * 1983-05-18 1988-03-01 Ortho Pharmaceutical Mutant human T cell line producing immunosuppressive factor and method for obtaining such mutants

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Biological Abstracts, Band 55, Nr. 1, 1973, (Philadelphia, PA., US), J.R. BATCHELOR: "Passive Enhancement of Kidney Allografts: Potentiation with Anti-Thymocyte Serum", siehe seite 266, Zusammenfassung 2407, & Transplantation 13(6): 610-613, 1972 *
Biological Abstracts, Band 61, Nr. 7, 1976, (Philadelphia, PA., US), J.W. FABRE et al.: "Prevention of Blood Transfusion-Induced Immunization against Transplantation Antigens by Treatment of the Blood with Antibody", siehe seite 3878, Zusammenfassung 37512, & Transplantation (Baltimore) 20(6): 473-479, 1975 *
Transplantation Proceedings, Band 17, Nr. 6, Dezember 1985, Grune & Stratton, Inc., P. TERNESS et al.: "Suppression of Antibody Response to Allogeneic Blood in Rats: a Model for Preventing Sensitization to Donor-Specific Transfusion", seiten 2409-2413 siehe den ganzen artikel *
Transplantation Proceedings, Band 17, Nr. 6, Dezember 1985, Grune & Stratton, Inc., R. SCHIFFL et al.: "Prolongation of Rat Kidney Graft Survival by Preconditioning with Antibody-Coated Cells", seiten 2414-2418 siehe den ganzen artikel *
Transplantation, Band 40, Nr. 4, 1985, The Williams & Wilkins Co., (US), P. TERNESS et al.: "Suppression of Antibody Response to Transfusions in Rats by Preconditioning with Antibody-Coated Cells", seiten 389-393 siehe seite 389, rechte spalte, zeile 17 - seite 390, linke spalte, zeile 9; seite 390, linke spalte, zeilen 34-43; seite 391, linke spalte, zeilen 3-14, 27-45; seite 392, linke spalte, zeilen 4-13, 25-30, 51-56 und rechte spalte, zeilen 5-9, 17-30 *

Also Published As

Publication number Publication date
US5004604A (en) 1991-04-02
JPH01500902A (ja) 1989-03-30
EP0277160A1 (fr) 1988-08-10
DE3626110A1 (de) 1988-02-11
WO1988000836A2 (fr) 1988-02-11

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