JPS6412279B2 - - Google Patents

Info

Publication number
JPS6412279B2
JPS6412279B2 JP55020348A JP2034880A JPS6412279B2 JP S6412279 B2 JPS6412279 B2 JP S6412279B2 JP 55020348 A JP55020348 A JP 55020348A JP 2034880 A JP2034880 A JP 2034880A JP S6412279 B2 JPS6412279 B2 JP S6412279B2
Authority
JP
Japan
Prior art keywords
muramyl
acetyl
methyl
peptide
alanyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55020348A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55113800A (en
Inventor
Rufuranshe Pieeru
Odeibeeru Furansowaazu
Shoai Jan
Shedeido Rui
Rudore Edogyaaru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU
Original Assignee
ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU filed Critical ANBAARU AJANSU NASHIONARU DO BARORIZASHION DO RA RUSHERUSHU
Publication of JPS55113800A publication Critical patent/JPS55113800A/ja
Publication of JPS6412279B2 publication Critical patent/JPS6412279B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2034880A 1979-02-20 1980-02-20 Muramyllpeptide type comound and drug containing it Granted JPS55113800A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7904316A FR2449697A1 (fr) 1979-02-20 1979-02-20 Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant

Publications (2)

Publication Number Publication Date
JPS55113800A JPS55113800A (en) 1980-09-02
JPS6412279B2 true JPS6412279B2 (enExample) 1989-02-28

Family

ID=9222210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2034880A Granted JPS55113800A (en) 1979-02-20 1980-02-20 Muramyllpeptide type comound and drug containing it

Country Status (5)

Country Link
US (1) US4427659A (enExample)
EP (1) EP0015810B1 (enExample)
JP (1) JPS55113800A (enExample)
DE (1) DE3066729D1 (enExample)
FR (1) FR2449697A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
JPS57144225A (en) * 1981-03-04 1982-09-06 Tadao Kokubu Antigenetic preparation for treating nonspecific allergic diseases and its preparation
US4933179A (en) * 1983-08-22 1990-06-12 Syntex (U.S.A.) Inc. Feline leukemia virus antigen vaccines
US4770874A (en) * 1983-08-22 1988-09-13 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4772466A (en) * 1983-08-22 1988-09-20 Syntex (U.S.A.) Inc. Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4765980A (en) * 1986-04-28 1988-08-23 International Minerals & Chemical Corp. Stabilized porcine growth hormone
US5554372A (en) * 1986-09-22 1996-09-10 Emory University Methods and vaccines comprising surface-active copolymers
US5416070A (en) * 1988-07-08 1995-05-16 Immunotherapeutics, Inc. Composition for macrophage activation
US4950645A (en) * 1988-07-08 1990-08-21 Immunotherapeutics, Inc. Composition for macrophage activation
CA2123912C (en) * 1991-11-19 2007-04-17 Roger Aston Muramyl compounds for treatment of septic shock
US5462735A (en) * 1993-06-10 1995-10-31 The United States Of America As Represented By The Secretary Of Agriculture Pasteurella haemolytica subunit vaccine containing capsular polysaccharide and muramyl dipeptide
US12134664B2 (en) 2015-12-10 2024-11-05 Bharat Biotech International Ltd. Muramyl peptide derivatives
CN108884132B (zh) 2015-12-10 2022-10-04 巴拉特生物技术国际有限公司 胞壁酰肽衍生物化合物、其合成及其用途
EP3389643B1 (en) * 2015-12-15 2023-05-03 Bharat Biotech International Limited Novel muramyl peptide derivative compound, synthesis and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2321896A1 (fr) 1975-08-29 1977-03-25 Anvar Agents adjuvants immunologiques actifs en solution aqueuse
FR2326930A1 (fr) 1975-10-09 1977-05-06 Anvar Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
CH613709A5 (en) 1975-12-10 1979-10-15 Ciba Geigy Ag Process for the preparation of glucosamine derivatives
US4082736A (en) 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
US4082735A (en) 1976-04-26 1978-04-04 Syntex (U.S.A.) Inc. Novel immunological adjuvant compounds and methods of preparation thereof
CH636887A5 (en) * 1976-04-26 1983-06-30 Syntex Inc Process for the preparation of novel immunological adjuvant compounds
GB1563561A (en) 1976-06-23 1980-03-26 Daiichi Seiyaku Co Muramyldipeptide derivatives and process for the preparation thereof
FR2368282A1 (fr) 1976-10-22 1978-05-19 Anvar Adjuvant immunologique constitue par le p-amino-phenyl de n-acetyl-muramyl-l-alanyl-d-isoglutamine
FI66878C (fi) 1978-02-24 1984-12-10 Ciba Geigy Ag Foerfarande foer framstaellning av nya antigenderivat

Also Published As

Publication number Publication date
DE3066729D1 (en) 1984-04-05
FR2449697A1 (fr) 1980-09-19
EP0015810A1 (fr) 1980-09-17
US4427659A (en) 1984-01-24
FR2449697B1 (enExample) 1982-07-09
EP0015810B1 (fr) 1984-02-29
JPS55113800A (en) 1980-09-02

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