JPS6362220B2 - - Google Patents
Info
- Publication number
- JPS6362220B2 JPS6362220B2 JP57043619A JP4361982A JPS6362220B2 JP S6362220 B2 JPS6362220 B2 JP S6362220B2 JP 57043619 A JP57043619 A JP 57043619A JP 4361982 A JP4361982 A JP 4361982A JP S6362220 B2 JPS6362220 B2 JP S6362220B2
- Authority
- JP
- Japan
- Prior art keywords
- low
- porous glass
- pore diameter
- density lipoprotein
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000011148 porous material Substances 0.000 claims description 40
- 239000005373 porous glass Substances 0.000 claims description 21
- 108010007622 LDL Lipoproteins Proteins 0.000 claims description 18
- 102000007330 LDL Lipoproteins Human genes 0.000 claims description 18
- 239000003463 adsorbent Substances 0.000 claims description 18
- 239000002245 particle Substances 0.000 claims description 10
- 125000000542 sulfonic acid group Chemical group 0.000 claims description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 26
- 235000012000 cholesterol Nutrition 0.000 description 12
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 11
- 102000004169 proteins and genes Human genes 0.000 description 9
- 108090000623 proteins and genes Proteins 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 229920001477 hydrophilic polymer Polymers 0.000 description 7
- -1 polyethylene Polymers 0.000 description 5
- 239000004743 Polypropylene Substances 0.000 description 4
- 229920001155 polypropylene Polymers 0.000 description 4
- 230000007423 decrease Effects 0.000 description 3
- 239000003456 ion exchange resin Substances 0.000 description 3
- 229920003303 ion-exchange polymer Polymers 0.000 description 3
- 238000001179 sorption measurement Methods 0.000 description 3
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 2
- 229920000936 Agarose Polymers 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 125000005372 silanol group Chemical group 0.000 description 2
- JHPBZFOKBAGZBL-UHFFFAOYSA-N (3-hydroxy-2,2,4-trimethylpentyl) 2-methylprop-2-enoate Chemical compound CC(C)C(O)C(C)(C)COC(=O)C(C)=C JHPBZFOKBAGZBL-UHFFFAOYSA-N 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 102000006395 Globulins Human genes 0.000 description 1
- 108010044091 Globulins Proteins 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 208000035150 Hypercholesterolemia Diseases 0.000 description 1
- 208000000563 Hyperlipoproteinemia Type II Diseases 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 102000000853 LDL receptors Human genes 0.000 description 1
- 108010001831 LDL receptors Proteins 0.000 description 1
- 102100024640 Low-density lipoprotein receptor Human genes 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 206010045261 Type IIa hyperlipidaemia Diseases 0.000 description 1
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 1
- 229920006222 acrylic ester polymer Polymers 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- OHJMTUPIZMNBFR-UHFFFAOYSA-N biuret Chemical compound NC(=O)NC(N)=O OHJMTUPIZMNBFR-UHFFFAOYSA-N 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 229940019700 blood coagulation factors Drugs 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 201000001386 familial hypercholesterolemia Diseases 0.000 description 1
- 238000002637 fluid replacement therapy Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000004388 gamma ray sterilization Methods 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000009395 genetic defect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 230000000260 hypercholesteremic effect Effects 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 108010022197 lipoprotein cholesterol Proteins 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- ZWLUXSQADUDCSB-UHFFFAOYSA-N phthalaldehyde Chemical compound O=CC1=CC=CC=C1C=O ZWLUXSQADUDCSB-UHFFFAOYSA-N 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57043619A JPS5826819A (ja) | 1982-03-17 | 1982-03-17 | 多孔性ガラスからなる低密度リポ蛋白質吸着剤 |
CA000418834A CA1189004A (en) | 1982-01-05 | 1983-01-04 | Vessel with a handle |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57043619A JPS5826819A (ja) | 1982-03-17 | 1982-03-17 | 多孔性ガラスからなる低密度リポ蛋白質吸着剤 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56126443A Division JPS5827559A (ja) | 1981-08-11 | 1981-08-11 | 低密度リポ蛋白質吸着剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5826819A JPS5826819A (ja) | 1983-02-17 |
JPS6362220B2 true JPS6362220B2 (de) | 1988-12-01 |
Family
ID=12668852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP57043619A Granted JPS5826819A (ja) | 1982-01-05 | 1982-03-17 | 多孔性ガラスからなる低密度リポ蛋白質吸着剤 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5826819A (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6884228B2 (en) | 2001-03-06 | 2005-04-26 | Baxter International Inc. | Automated system adaptable for use with different fluid circuits |
US6582386B2 (en) | 2001-03-06 | 2003-06-24 | Baxter International Inc. | Multi-purpose, automated blood and fluid processing systems and methods |
JP4226050B1 (ja) * | 2007-09-12 | 2009-02-18 | 株式会社Reiメディカル | 体液浄化処理用吸着カラム |
-
1982
- 1982-03-17 JP JP57043619A patent/JPS5826819A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5826819A (ja) | 1983-02-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4472303A (en) | Blood purification method | |
US7311845B2 (en) | Adsorbing material for blood and plasma cleaning method and for albumin purification | |
EP1621220B1 (de) | Lipoprotein niederer dichte/fibrinogen adsorbens und gerät für die vollblutbehandlung | |
JPS5827559A (ja) | 低密度リポ蛋白質吸着剤 | |
JPS6362220B2 (de) | ||
JPH0977790A (ja) | 糖脂質抗体吸着材 | |
JPS6319214B2 (de) | ||
JPS63160669A (ja) | 低密度リポ蛋白質吸着剤 | |
JPS59139936A (ja) | イムノグロブリンg吸着剤 | |
JPH08173803A (ja) | エンドトキシンの吸着剤、吸着除去方法および吸着器 | |
JPS63209663A (ja) | 体液処理装置の滅菌方法および滅菌された体液処理装置 | |
JPS6222659A (ja) | 低比重リポ蛋白質吸着材の再生方法 | |
JPS59156431A (ja) | 吸着体 | |
US7348294B2 (en) | Adsorbent and method for adsorbing cardiac glycoside | |
JP2584261B2 (ja) | ヘモグロビンの吸着剤 | |
JPH043988B2 (de) | ||
JPS5838562A (ja) | 体液処理用蛋白質吸着剤の再生方法及びそのための装置 | |
JPH0611324B2 (ja) | 多孔質中空糸膜 | |
JPS63283748A (ja) | ミオグロビン吸着材 | |
JPH09220281A (ja) | 体液処理装置の滅菌方法および滅菌された体液処理装置 | |
JPS62244442A (ja) | 低比重リポ蛋白質吸着材およびその製造方法 | |
JPH088928B2 (ja) | 低比重リポ蛋白質を除去した血漿を製造する装置 | |
JPS59139935A (ja) | 低比重リポ蛋白の吸着材 | |
JPS59141524A (ja) | 抗体吸着剤 | |
JPH0640899B2 (ja) | 吸着体の製造法 |