JPS63258597A - ジヒドロ葉酸還元酵素−ソマトスタチン融合タンパク及びその製造方法 - Google Patents

ジヒドロ葉酸還元酵素−ソマトスタチン融合タンパク及びその製造方法

Info

Publication number
JPS63258597A
JPS63258597A JP9288187A JP9288187A JPS63258597A JP S63258597 A JPS63258597 A JP S63258597A JP 9288187 A JP9288187 A JP 9288187A JP 9288187 A JP9288187 A JP 9288187A JP S63258597 A JPS63258597 A JP S63258597A
Authority
JP
Japan
Prior art keywords
fusion protein
gif
dhfr
protein
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9288187A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0364110B2 (enrdf_load_stackoverflow
Inventor
Masahiro Iwakura
正寛 巖倉
Tomokuni Kokubu
国分 友邦
Kiyotaka Furusawa
古澤 清孝
Shinichi Ohashi
信一 大箸
Keishiro Tsuda
津田 圭四郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Original Assignee
Agency of Industrial Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency of Industrial Science and Technology filed Critical Agency of Industrial Science and Technology
Priority to JP9288187A priority Critical patent/JPS63258597A/ja
Publication of JPS63258597A publication Critical patent/JPS63258597A/ja
Publication of JPH0364110B2 publication Critical patent/JPH0364110B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP9288187A 1987-04-15 1987-04-15 ジヒドロ葉酸還元酵素−ソマトスタチン融合タンパク及びその製造方法 Granted JPS63258597A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9288187A JPS63258597A (ja) 1987-04-15 1987-04-15 ジヒドロ葉酸還元酵素−ソマトスタチン融合タンパク及びその製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9288187A JPS63258597A (ja) 1987-04-15 1987-04-15 ジヒドロ葉酸還元酵素−ソマトスタチン融合タンパク及びその製造方法

Publications (2)

Publication Number Publication Date
JPS63258597A true JPS63258597A (ja) 1988-10-26
JPH0364110B2 JPH0364110B2 (enrdf_load_stackoverflow) 1991-10-03

Family

ID=14066792

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9288187A Granted JPS63258597A (ja) 1987-04-15 1987-04-15 ジヒドロ葉酸還元酵素−ソマトスタチン融合タンパク及びその製造方法

Country Status (1)

Country Link
JP (1) JPS63258597A (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
JPH0364110B2 (enrdf_load_stackoverflow) 1991-10-03

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term