JPS63141915A - Hair-tonic - Google Patents
Hair-tonicInfo
- Publication number
- JPS63141915A JPS63141915A JP61289480A JP28948086A JPS63141915A JP S63141915 A JPS63141915 A JP S63141915A JP 61289480 A JP61289480 A JP 61289480A JP 28948086 A JP28948086 A JP 28948086A JP S63141915 A JPS63141915 A JP S63141915A
- Authority
- JP
- Japan
- Prior art keywords
- hair
- tonic
- oridonin
- skin
- isodon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- SDHTXBWLVGWJFT-XKCURVIJSA-N oridonin Chemical compound C([C@@H]1[C@@H](O)[C@@]23C(C1=C)=O)C[C@H]2[C@]12[C@@H](O)CCC(C)(C)[C@H]1[C@H](O)[C@@]3(O)OC2 SDHTXBWLVGWJFT-XKCURVIJSA-N 0.000 claims abstract description 20
- CAQAFLRZJHXSIS-UHFFFAOYSA-N oridonin Natural products CC1(C)C=CC(O)C23COC(O)(C(O)C12)C45C(O)C(CCC34)C(=C)C5=O CAQAFLRZJHXSIS-UHFFFAOYSA-N 0.000 claims abstract description 20
- 210000004209 hair Anatomy 0.000 claims description 28
- 230000000694 effects Effects 0.000 abstract description 16
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract description 4
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 3
- 241000207923 Lamiaceae Species 0.000 abstract description 3
- 241000196324 Embryophyta Species 0.000 abstract description 2
- 238000004440 column chromatography Methods 0.000 abstract description 2
- 230000007794 irritation Effects 0.000 abstract description 2
- 238000010992 reflux Methods 0.000 abstract description 2
- 238000001914 filtration Methods 0.000 abstract 2
- 206010012434 Dermatitis allergic Diseases 0.000 abstract 1
- 241001183967 Isodon Species 0.000 abstract 1
- 241001365031 Isodon japonicus Species 0.000 abstract 1
- 241001365032 Isodon trichocarpus Species 0.000 abstract 1
- 208000030961 allergic reaction Diseases 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 description 8
- 238000002474 experimental method Methods 0.000 description 7
- 239000004615 ingredient Substances 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 241000699670 Mus sp. Species 0.000 description 5
- 239000006210 lotion Substances 0.000 description 4
- 239000006071 cream Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- 208000010201 Exanthema Diseases 0.000 description 2
- 241000234295 Musa Species 0.000 description 2
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 201000005884 exanthem Diseases 0.000 description 2
- 230000003779 hair growth Effects 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 229940098465 tincture Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 240000007124 Brassica oleracea Species 0.000 description 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
- 208000019300 CLIPPERS Diseases 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 241000219793 Trifolium Species 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000001390 capsicum minimum Substances 0.000 description 1
- 208000021930 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids Diseases 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 229940075507 glyceryl monostearate Drugs 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 239000003504 photosensitizing agent Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229930007845 β-thujaplicin Natural products 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明は養毛料、さらに詳しくは、いわゆる延命草と称
されるしそ科ヤマハツカ属のヒキオコシやクロバナヒキ
オコシ等からの特定の抽出成分を必須成分とする養毛料
に関する。DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention provides a hair nourishing agent, more specifically, a hair tonic containing a specific extracted component from the so-called Enmeiso, which belongs to the Lamiaceae family, the genus Yamahathatsuka, and the like. Regarding hair nourishment.
（従来の技術） 従来、養毛料としては、゛たとえばエタノール。(Conventional technology) Traditionally, ethanol was used as a hair nourishing agent.
女性ホルモン、ビタミンＢ６＋ ビタミンＥ、パントテ
ン酸、トウガラシチンキ、ショウキョウチンキ、センブ
リエキス、ヒノキチオール、感光素。Female hormones, vitamin B6+, vitamin E, pantothenic acid, capsicum tincture, ginger tincture, Japanese cabbage extract, hinokitiol, photosensitizer.
オードキニン等の成分を含むものが数多（市販されてい
る。There are many commercially available products containing ingredients such as ordokinin.
（発明が解決しようとする問題点）
しかしながら、上記のような成分は、いずれも頭部、よ
り詳細には頭髪の生え際の血行を促進することによって
養毛効果を図らんとするもので、実際上、外用としての
養毛効果はほとんど認めることはできなかった。又、上
記成分中でも女性ホルモンは柱体への影響から配合量が
限定されており、養毛効果が認められるだけの量は同腹
配合できないものであった。(Problems to be Solved by the Invention) However, all of the above-mentioned ingredients are intended to have a hair-nourishing effect by promoting blood circulation to the head, more specifically to the hairline; Above all, almost no hair growth effect could be observed when used externally. Furthermore, among the above ingredients, the amount of female hormones to be included is limited due to their influence on the columnar bodies, and it has not been possible to include them in the same amount in the same litter to have a recognized hair-nourishing effect.
さらに、上記のような成分を含む養毛料は、配合量によ
ってはアレルギーやかぶれ等を生ずるという問題も生し
ていた。Furthermore, hair nourishing products containing the above-mentioned components have the problem of causing allergies, rashes, etc., depending on the amount of the ingredients.
本発明は、上述のような問題点をすべて解決するために
なされたもので、外用としての養毛効果が明確且つ顕著
に認められ、且つ皮膚に対する刺激がなく極めて安全性
の高い養毛料を提供することを目的とするものである。The present invention has been made in order to solve all of the above-mentioned problems, and provides a hair nourishing agent that has a clear and significant hair nourishing effect when used externally, and is extremely safe as it does not irritate the skin. The purpose is to
（問題点を解決するための手段）
本発明は、このような目的を達成すべく、延命草と称さ
れるヒキオコシ、クロバナヒキオコシ等からの抽出成分
であるオリドニンに養毛効果があることに着目し、この
観点から上記問題点を解決せんとしてなされたもので、
その問題点を解決するための手段は、養毛料に少なくと
も前記オリドニンを含ませることにある。(Means for Solving the Problems) In order to achieve the above object, the present invention focuses on the fact that oridonin, which is an extracted component from Hikiokoshi, Black Banana Hikiokoshi, etc. called Enmeiso, has a hair-nourishing effect. , was made in an attempt to solve the above problems from this point of view,
A means to solve this problem is to include at least the above-mentioned oridonin in the hair nourishment.
（実施例） 以下、本発明の実施例について説明する。(Example) Examples of the present invention will be described below.
１施史上
一実施例としての養毛料は、ローションタイプのもので
、そのローション中の各成分は次のとおりである。1. The hair nourishing agent as an example of treatment history is a lotion type, and the ingredients in the lotion are as follows.
オリドニン ０．２ｇエンメイン
０．１ ｇグリチルリチン酸ジ
カリウム ｏ、ｏｓ ｇブチレングリコール
３．０ｇエタノール ４０．０
ｇ以上の成分に精製水を加えて全量を１００ ｍ ｌ
とした。Oridonin 0.2g Enmain
0.1 g dipotassium glycyrrhizinate o, os g butylene glycol
3.0g ethanol 40.0
Add purified water to more than g of ingredients to make the total volume 100ml
And so.
尚、上記オリドニンとエンメインは、共にしそ科ヤマハ
ツカ属のヒキオコシ及び／又はクロバナヒキオコシから
の抽出成分であり、その精製方法は次のとおりである。The above-mentioned oridonin and enmain are both components extracted from Hikiokoshi and/or Clover Hikiokoshi of the family Lamiaceae, genus Yamahathuka, and the purification method thereof is as follows.
すなわち、上記ヒキオコシ及び／又はクロバナヒキオコ
シの乾燥葉、茎部を細く砕き、メタノールで還流抽出し
、次に２〜５時間経過後、濾過し活性炭処理を行った後
、再度濾過して抽出液を減圧濃縮し、粗結晶を得る。そ
の後、この粗結晶をカラムクロマトグラムで精製するこ
とによって、抽出成分としてのオリドニンとエンメイン
が得られるのである。That is, the dried leaves and stems of the above-mentioned Hikiokoshi and/or Black-bellied Hikiokoshi are finely crushed, extracted under reflux with methanol, and then after 2 to 5 hours have passed, they are filtered and treated with activated carbon, and then filtered again and the extract is depressurized. Concentrate to obtain crude crystals. Thereafter, by refining the crude crystals using column chromatography, oridonin and enmain can be obtained as extracted components.
スＪ１１１
本実施例における養毛料は、クリームタイプのもので、
その各成分は次のとおりである。SJ111 The hair nourishing agent in this example is a cream type.
Its components are as follows.
オリドニン ０．２ｇエンメイン
０．１ ｇステアリン酸
４ｇ
セタノール ４ｇ
モノステアリン酸グリセリン ２ｇ
イソプロピルミリステート ６ｇ
ブチレングリコール ６ｇ
トリエタノールアミン １ｇ
パラオキシ安息香酸メチル ０．２ ｇ以上の成分
に精製水を加えて全量を１００ｇとした。Oridonin 0.2g Enmain
0.1 g stearic acid
4g Setanol 4g Glyceryl monostearate 2g Isopropyl myristate 6g Butylene glycol 6g Triethanolamine 1g Methyl paraoxybenzoate 0.2g or more of the ingredients were added with purified water to make the total amount 100g.
尚、オリドニンとエンメインの精製方法は、上記実施例
１と同様である。The method for purifying oridonin and enmain is the same as in Example 1 above.
そして、オリドニン又はオリドニンとエンメインの混合
成分について動物実験を行ったところ、次表のような結
果を得た。When animal experiments were conducted on oridonin or a mixed component of oridonin and enmain, the results shown in the following table were obtained.
（率−危険率１０％で有意）
（本＊−危険率５％で有意）
以上の結果により、貧毛マウスを用いた実験においては
、実験開始日から２８日経過後の毛長が実験前の毛長よ
りも長くなる等、毛髪の生長促進作用が明らかに認めら
れた。又、市販の医薬品と比較してもその養毛効果の差
異並びに持続性が認められている。さらに、安全性に関
しても全く刺激は認められなかった。(Rate - Significant at a risk rate of 10%) (Book* - Significant at a risk rate of 5%) Based on the above results, in the experiment using hypohair mice, the hair length after 28 days from the start of the experiment was the same as before the experiment. The hair growth-promoting effect was clearly observed, as the hair became longer than the hair length. Furthermore, when compared with commercially available pharmaceuticals, the difference and sustainability of the hair growth effect has been recognized. Furthermore, regarding safety, no irritation was observed.
尚、上記の実験方法について説明すると次のとおりであ
る。The above experimental method will be explained as follows.
６〜７週令の貧毛マウス（ａ）５匹を１群として用いる
。試験は背部で行う。実験前に毛を抜き、その平均長を
求める。次いで、試験部位の毛を抜き、残毛はバリカン
で刈る。皮膚の状態に異常のないことを確認して試験を
始める。Five 6- to 7-week-old hypohair mice (a) are used as one group. The test is performed on the back. Before the experiment, pull out the hairs and find their average length. The hair at the test site is then removed and the remaining hair is clipped with clippers. The test begins after confirming that there are no abnormalities in the skin condition.
１日１回サンプルを塗布し、毎朝、生育上の状態を観察
記録した。実験開始日より２週間経過後から定期的に毛
を抜き（５〜１０本）、その長さを測定する。但し、比
較はサンプル塗布のマウスの群れ（５匹）と対照群（コ
ントロールとして３５％エタノールを塗布したマウス５
匹）とで行った。Samples were applied once a day, and growth conditions were observed and recorded every morning. Two weeks after the start of the experiment, the hairs are regularly pulled out (5 to 10 hairs) and their lengths are measured. However, the comparison was made between a group of mice applied with the sample (5 mice) and a control group (5 mice applied with 35% ethanol as a control).
I went with a fish).
尚、上記実施例１，２では養毛材中に、オリドニンとと
もにエンメインを含有してなるが、エンメインを含有せ
ずにオリドニンのみを含有したものであってもよい。要
は、少なくともオリドニンが養毛材中に含まれていれば
よいのである。そしてオリドニンのみを含む場合であっ
ても、オリドニン及びエンメインの双方を含む場合と同
等の養毛効果が得られることは上記実験データからも明
らかである。In Examples 1 and 2, the hair nourishing material contains enmain together with oridonin, but it may contain only oridonin without enmain. In short, it is sufficient that at least oridonin is contained in the hair nourishing material. It is also clear from the above experimental data that even when only oridonin is contained, the same hair-nourishing effect as when both oridonin and enmain are contained can be obtained.
又、上記各実施例では、ヒキオコシ及び／又はクロバナ
ヒキオコシから抽出したオリドニンを使用してなるが、
これ以外の植物から抽出したオリドニンを使用すること
も可能である。In addition, in each of the above Examples, oridonin extracted from Hikiokoshi and/or Black Banana Hikiokoshi is used,
It is also possible to use oridonin extracted from other plants.
さらに、ローション、クリーム等の各成分の組成や配合
比等も決して上記実施例に限定されるものではなく、又
、基剤の種類も該実施例のローション、クリームに限定
されるものではなく、基剤の種類は問わない。Furthermore, the composition and blending ratio of each component of the lotion, cream, etc. are not limited to the above examples, and the type of base is not limited to the lotions, creams, etc. of the examples. The type of base material does not matter.
（発明の効果）
（イ）叙上のように、本発明は、養毛料に少なくともオ
リドニンが含まれているため、外用としての明らかな養
毛効果が認められ、実際上効果の認められなかった従来
市販の養毛料に比べると、その養毛効果が著しく優れた
ものになるという顕著な効果を有するに至った。(Effects of the invention) (a) As mentioned above, since the hair nourishing agent of the present invention contains at least oridonin, a clear hair nourishing effect was observed when used externally, but no effect was observed in practice. Compared to conventional hair nourishing products on the market, the hair nourishing effect has been significantly improved.
（ロ）さらに、皮膚に対する刺激もなく、又従来の養毛
料のようなアレルギーやかぶれ等を生しさせるおそれも
なく、極めて安全性の高い養毛料を提供しうるに至った
のである。(b) Furthermore, it has become possible to provide an extremely safe hair nourishing agent that does not irritate the skin or cause allergies or rashes unlike conventional hair nourishing agents.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61289480A JPS63141915A (en) | 1986-12-03 | 1986-12-03 | Hair-tonic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61289480A JPS63141915A (en) | 1986-12-03 | 1986-12-03 | Hair-tonic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS63141915A true JPS63141915A (en) | 1988-06-14 |
Family
ID=17743820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61289480A Pending JPS63141915A (en) | 1986-12-03 | 1986-12-03 | Hair-tonic |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63141915A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2944435A1 (en) * | 2009-04-17 | 2010-10-22 | Sederma Sa | COSMETIC COMPOSITION COMPRISING ORIDONIN |
-
1986
- 1986-12-03 JP JP61289480A patent/JPS63141915A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2944435A1 (en) * | 2009-04-17 | 2010-10-22 | Sederma Sa | COSMETIC COMPOSITION COMPRISING ORIDONIN |
| WO2010119423A3 (en) * | 2009-04-17 | 2011-05-19 | Sederma | Cosmetic compositions comprising oridonin and new cosmetic uses |
| US9050477B2 (en) | 2009-04-17 | 2015-06-09 | Sederma | Cosmetic compositions comprising oridonin and new cosmetic uses |
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