JPS63115554A - 擬内膜形成性に優れた人工血管及びその製法 - Google Patents
擬内膜形成性に優れた人工血管及びその製法Info
- Publication number
- JPS63115554A JPS63115554A JP61260718A JP26071886A JPS63115554A JP S63115554 A JPS63115554 A JP S63115554A JP 61260718 A JP61260718 A JP 61260718A JP 26071886 A JP26071886 A JP 26071886A JP S63115554 A JPS63115554 A JP S63115554A
- Authority
- JP
- Japan
- Prior art keywords
- artificial blood
- blood vessel
- fibers
- less
- pseudointima
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004204 blood vessel Anatomy 0.000 title claims description 59
- 239000002473 artificial blood Substances 0.000 title claims description 52
- 239000000835 fiber Substances 0.000 claims description 36
- 230000015572 biosynthetic process Effects 0.000 claims description 25
- 229920001410 Microfiber Polymers 0.000 claims description 21
- 238000004519 manufacturing process Methods 0.000 claims description 14
- 238000009832 plasma treatment Methods 0.000 claims description 10
- 238000009736 wetting Methods 0.000 claims description 9
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 4
- 239000001913 cellulose Substances 0.000 claims description 4
- 238000009941 weaving Methods 0.000 claims description 4
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims description 3
- 229920001661 Chitosan Polymers 0.000 claims description 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000000783 alginic acid Substances 0.000 claims description 3
- 229920000615 alginic acid Polymers 0.000 claims description 3
- 229960001126 alginic acid Drugs 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 229920002101 Chitin Polymers 0.000 claims description 2
- 235000010443 alginic acid Nutrition 0.000 claims description 2
- 150000004781 alginic acids Chemical class 0.000 claims description 2
- 238000009954 braiding Methods 0.000 claims 1
- 238000009940 knitting Methods 0.000 claims 1
- 210000004369 blood Anatomy 0.000 description 27
- 239000008280 blood Substances 0.000 description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 25
- 238000000034 method Methods 0.000 description 22
- 102000009123 Fibrin Human genes 0.000 description 21
- 108010073385 Fibrin Proteins 0.000 description 21
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 21
- 229950003499 fibrin Drugs 0.000 description 21
- 230000035699 permeability Effects 0.000 description 11
- 229920000642 polymer Polymers 0.000 description 11
- 230000000694 effects Effects 0.000 description 10
- 208000007536 Thrombosis Diseases 0.000 description 7
- -1 polytetrafluoroethylene Polymers 0.000 description 7
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 229920000139 polyethylene terephthalate Polymers 0.000 description 5
- 239000005020 polyethylene terephthalate Substances 0.000 description 5
- 102000008946 Fibrinogen Human genes 0.000 description 4
- 108010049003 Fibrinogen Proteins 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 229940012952 fibrinogen Drugs 0.000 description 4
- 230000002785 anti-thrombosis Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 230000002209 hydrophobic effect Effects 0.000 description 3
- 210000004379 membrane Anatomy 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 241000239290 Araneae Species 0.000 description 2
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 206010053567 Coagulopathies Diseases 0.000 description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 230000023555 blood coagulation Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 229920000098 polyolefin Polymers 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 229930182556 Polyacetal Natural products 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004734 Polyphenylene sulfide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 240000005578 Rivina humilis Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000004954 endothelial membrane Anatomy 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010559 graft polymerization reaction Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 229920000069 polyphenylene sulfide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- PUVAFTRIIUSGLK-UHFFFAOYSA-M trimethyl(oxiran-2-ylmethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CC1CO1 PUVAFTRIIUSGLK-UHFFFAOYSA-M 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61260718A JPS63115554A (ja) | 1986-11-04 | 1986-11-04 | 擬内膜形成性に優れた人工血管及びその製法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61260718A JPS63115554A (ja) | 1986-11-04 | 1986-11-04 | 擬内膜形成性に優れた人工血管及びその製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63115554A true JPS63115554A (ja) | 1988-05-20 |
| JPH0548132B2 JPH0548132B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-07-20 |
Family
ID=17351793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61260718A Granted JPS63115554A (ja) | 1986-11-04 | 1986-11-04 | 擬内膜形成性に優れた人工血管及びその製法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63115554A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03254752A (ja) * | 1989-12-13 | 1991-11-13 | Korea Res Inst Of Chem Technol | 人工血管及びその製造方法 |
| WO2001070292A1 (fr) * | 2000-03-24 | 2001-09-27 | Yuichi Mori | Organe artificiel creux |
| WO2014038219A1 (ja) * | 2012-09-07 | 2014-03-13 | 有限会社ナイセム | 長期間生体内植え込み用極細繊維製医療材料 |
| WO2014168198A1 (ja) * | 2013-04-12 | 2014-10-16 | 東レ株式会社 | 抗血栓性を有する人工血管 |
| EP2985041A4 (en) * | 2013-04-12 | 2016-10-19 | Toray Industries | ANTITOMOMOTIVE ARTIFICIAL BLOOD VESSEL |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0945145A (ja) * | 1995-08-01 | 1997-02-14 | Nec Corp | 電磁放射対策ケーブル，それに用いるコネクタ，及びケーブル接続構造 |
| JP6520706B2 (ja) | 2014-02-12 | 2019-05-29 | 東レ株式会社 | 人工血管 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5493121A (en) * | 1977-12-12 | 1979-07-24 | Akzo Nv | Hydrophilic polyester fiber and production thereof |
| JPS56157437A (en) * | 1980-05-07 | 1981-12-04 | Sumitomo Electric Ind Ltd | Preparation of hydrophilic porous structure |
| JPS5945328A (ja) * | 1982-09-07 | 1984-03-14 | Kanebo Ltd | 高分子間錯体を表面に有するフイルム及びその製造方法 |
| JPS6077764A (ja) * | 1983-10-05 | 1985-05-02 | 東レ株式会社 | 人工血管 |
-
1986
- 1986-11-04 JP JP61260718A patent/JPS63115554A/ja active Granted
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5493121A (en) * | 1977-12-12 | 1979-07-24 | Akzo Nv | Hydrophilic polyester fiber and production thereof |
| JPS56157437A (en) * | 1980-05-07 | 1981-12-04 | Sumitomo Electric Ind Ltd | Preparation of hydrophilic porous structure |
| JPS5945328A (ja) * | 1982-09-07 | 1984-03-14 | Kanebo Ltd | 高分子間錯体を表面に有するフイルム及びその製造方法 |
| JPS6077764A (ja) * | 1983-10-05 | 1985-05-02 | 東レ株式会社 | 人工血管 |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03254752A (ja) * | 1989-12-13 | 1991-11-13 | Korea Res Inst Of Chem Technol | 人工血管及びその製造方法 |
| US5415619A (en) * | 1989-12-13 | 1995-05-16 | Korea Research Institute Of Chemical Tech. | Method of manufacturing a vascular graft impregnated with polysaccharide derivatives |
| WO2001070292A1 (fr) * | 2000-03-24 | 2001-09-27 | Yuichi Mori | Organe artificiel creux |
| WO2014038219A1 (ja) * | 2012-09-07 | 2014-03-13 | 有限会社ナイセム | 長期間生体内植え込み用極細繊維製医療材料 |
| JP2014050568A (ja) * | 2012-09-07 | 2014-03-20 | Naisemu:Kk | 長期間生体内植え込み用極細繊維製医療材料 |
| WO2014168198A1 (ja) * | 2013-04-12 | 2014-10-16 | 東レ株式会社 | 抗血栓性を有する人工血管 |
| EP2985042A4 (en) * | 2013-04-12 | 2016-10-19 | Toray Industries | ARTIFICIAL BLOOD VESSEL ANTITHROMBOTIC |
| EP2985041A4 (en) * | 2013-04-12 | 2016-10-19 | Toray Industries | ANTITOMOMOTIVE ARTIFICIAL BLOOD VESSEL |
| JPWO2014168198A1 (ja) * | 2013-04-12 | 2017-02-16 | 東レ株式会社 | 抗血栓性を有する人工血管 |
| US9662233B2 (en) | 2013-04-12 | 2017-05-30 | Toray Industries, Inc. | Antithrombotic artificial blood vessel |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0548132B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-07-20 |
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| THOMAS | Biological Activity of Adsorbed Proteins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| S801 | Written request for registration of abandonment of right |
Free format text: JAPANESE INTERMEDIATE CODE: R311801 |
|
| ABAN | Cancellation due to abandonment | ||
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |