JPS62175142A - Additive for fish farming feed - Google Patents
Additive for fish farming feedInfo
- Publication number
- JPS62175142A JPS62175142A JP61016739A JP1673986A JPS62175142A JP S62175142 A JPS62175142 A JP S62175142A JP 61016739 A JP61016739 A JP 61016739A JP 1673986 A JP1673986 A JP 1673986A JP S62175142 A JPS62175142 A JP S62175142A
- Authority
- JP
- Japan
- Prior art keywords
- ascorbic acid
- feed
- fish
- additive
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000654 additive Substances 0.000 title claims abstract description 4
- 230000000996 additive effect Effects 0.000 title claims abstract description 4
- 238000009372 pisciculture Methods 0.000 title description 2
- 241000251468 Actinopterygii Species 0.000 claims abstract description 17
- 150000003839 salts Chemical class 0.000 claims abstract description 8
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- MIJPAVRNWPDMOR-ZAFYKAAXSA-N L-ascorbic acid 2-phosphate Chemical compound OC[C@H](O)[C@H]1OC(=O)C(OP(O)(O)=O)=C1O MIJPAVRNWPDMOR-ZAFYKAAXSA-N 0.000 claims 1
- 235000019688 fish Nutrition 0.000 abstract description 14
- 241000277275 Oncorhynchus mykiss Species 0.000 abstract description 8
- 241000861914 Plecoglossus altivelis Species 0.000 abstract description 4
- 150000002148 esters Chemical class 0.000 abstract description 4
- 241000277329 Oncorhynchus keta Species 0.000 abstract description 3
- 241001600434 Plectroglyphidodon lacrymatus Species 0.000 abstract description 3
- 241000972773 Aulopiformes Species 0.000 abstract 2
- 235000019515 salmon Nutrition 0.000 abstract 2
- 241000473391 Archosargus rhomboidalis Species 0.000 abstract 1
- 241000252233 Cyprinus carpio Species 0.000 abstract 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 39
- 239000011668 ascorbic acid Substances 0.000 description 18
- 229960005070 ascorbic acid Drugs 0.000 description 18
- 235000010323 ascorbic acid Nutrition 0.000 description 17
- 229940088594 vitamin Drugs 0.000 description 6
- 229930003231 vitamin Natural products 0.000 description 6
- 235000013343 vitamin Nutrition 0.000 description 6
- 239000011782 vitamin Substances 0.000 description 6
- 230000000366 juvenile effect Effects 0.000 description 5
- 206010047623 Vitamin C deficiency Diseases 0.000 description 4
- 230000035611 feeding Effects 0.000 description 4
- 208000010233 scurvy Diseases 0.000 description 4
- 208000006770 Ascorbic Acid Deficiency Diseases 0.000 description 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 3
- 235000019733 Fish meal Nutrition 0.000 description 3
- 229930003268 Vitamin C Natural products 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000004467 fishmeal Substances 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 235000019154 vitamin C Nutrition 0.000 description 3
- 239000011718 vitamin C Substances 0.000 description 3
- 150000003722 vitamin derivatives Chemical class 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- 241000277331 Salmonidae Species 0.000 description 2
- -1 ascorbic acid-2-phosphate magnesium salt Chemical class 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 208000001936 exophthalmos Diseases 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 241000252073 Anguilliformes Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000283725 Bos Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 150000000996 L-ascorbic acids Chemical class 0.000 description 1
- 241000442132 Lactarius lactarius Species 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 241000131739 Oncorhynchus masou rhodurus Species 0.000 description 1
- 241001282110 Pagrus major Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- NCYCYZXNIZJOKI-OVSJKPMPSA-N Retinaldehyde Chemical compound O=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 description 1
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229940087168 alpha tocopherol Drugs 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 1
- 229960002079 calcium pantothenate Drugs 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 229960002061 ergocalciferol Drugs 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 210000002816 gill Anatomy 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 230000001418 larval effect Effects 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 230000006371 metabolic abnormality Effects 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 1
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 1
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 1
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 1
- 235000020945 retinal Nutrition 0.000 description 1
- 239000011604 retinal Substances 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 229960000344 thiamine hydrochloride Drugs 0.000 description 1
- 235000019190 thiamine hydrochloride Nutrition 0.000 description 1
- 239000011747 thiamine hydrochloride Substances 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
Abstract
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明はニジマス、ヒメマス、シロザケ、アユ、するも
のである。DETAILED DESCRIPTION OF THE INVENTION (Industrial Field of Application) The present invention is directed to rainbow trout, lesser trout, chum salmon, and sweetfish.
（従来技術）
魚類でのビタミンＣに関する研究は近年各方面で行なわ
れるようになった。１９６２年に各地のニジマス養魚場
で背椎のわん曲な主機とする異常前が多発したが、研究
の結果アスコルビン酸（ビタミンＣ）の不足によるもの
であることが証明された（日本水産学会誌第３１巻第８
１８頁〜８２６頁）。さらに昭和４２年日本水産学会年
会でニジマス、ヒメマスおよびシロザケ稚魚のアスコル
ビン酸欠乏による変形症の報告などがある。また、アユ
では食欲不振、軽度の眼球突出、ヒレ基部の出血、（偲
蓋（えらぶた）、下顎部の損傷などの欠乏症、ハマチ稚
魚では摂餌量減少、成長停止、背椎わん曲、体色黒変、
高へい死率などの欠乏症、ウナギでは食欲低下、成長停
滞のほかヒレ、頭部の出血などがおこる。そのため、養
魚用飼料にはアスコルビン酸を含むビタミン類が添加さ
れ、給餌されている。ところが、アスコルビン酸は水溶
性ビタミンの中でも特に不安定なものであるため、飼料
中に添加した場合に分解が起る。魚粉中では特に不安定
であシ、ニジマス用飼料のように魚粉が半ば以上を占め
るような配合のものでは分解によるビタミンＣの力価の
低下の問題は非常に大きい。(Prior Art) In recent years, research on vitamin C in fish has been conducted in various fields. In 1962, abnormalities caused by curved dorsal vertebrae occurred frequently at rainbow trout fish farms across the country, but research proved that this was due to a lack of ascorbic acid (vitamin C) (Journal of the Japanese Society of Fisheries Science) Volume 31, No. 8
18-826). Furthermore, at the annual meeting of the Japan Fisheries Society in 1962, there were reports of deformities caused by ascorbic acid deficiency in juvenile rainbow trout, red trout, and chum salmon. In addition, deficiencies such as loss of appetite, mild proptosis of the eyes, bleeding at the base of the fins, and damage to the gills and lower jaw are observed in sweetfish, and in juvenile yellowtail, decreased food intake, growth arrest, dorsal curvature, and body dark complexion,
Deficiency symptoms include a high mortality rate, and in eels, symptoms include decreased appetite, stagnation in growth, and bleeding in the fins and head. Therefore, vitamins containing ascorbic acid are added to fish feed. However, since ascorbic acid is particularly unstable among water-soluble vitamins, it decomposes when added to feed. It is particularly unstable in fishmeal, and in feeds for rainbow trout where more than half of the content is made up of fishmeal, the problem of a decrease in the titer of vitamin C due to decomposition is very serious.
（発明が解決しようとする問題点）
上記の事情にかんがみ、本発明者らは安定でかつ、アス
コルビン酸の活性を充分に有する養魚用飼料添加物の研
究を重ねた結果、Ｌ−アスコルビン酸−２−リン酸エス
テルまたはその塩類を養魚用飼料中に添加した場合に、
極めて安定でアスコルビン酸の力価の低下がほとんどな
いことを発見し、さらにこのし−アスコルビン酸−２−
ＩＪン［エステルまたはその塩、例えばナトリウム、カ
リウム、カルシウム、マグネシウム塩等、を含有する養
魚用飼料で各魚種を飼育したところ、アスコルビン酸欠
乏による背椎わん曲、眼球突出などの壊血病症状を防止
し、へい死率な極端に低下させ、平均体重を増加させる
などの好結果をもたらすことを見い出し本発明を完成し
た。(Problems to be Solved by the Invention) In view of the above circumstances, the present inventors have repeatedly conducted research into fish feed additives that are stable and have sufficient ascorbic acid activity. When 2-phosphate ester or its salts are added to fish feed,
They discovered that this ascorbic acid is extremely stable and there is almost no decrease in the titer of ascorbic acid.
When various fish species were raised with fish feed containing IJ ester or its salts, such as sodium, potassium, calcium, and magnesium salts, scurvy such as dorsal curvature and proptosis of the eyes due to ascorbic acid deficiency was observed. The present invention was completed after discovering that the present invention can bring about favorable results such as preventing symptoms, extremely reducing mortality rate, and increasing average body weight.
（問題点を解決するだめの具体的手段）本発明は飼料中
で極めて安定でかつアスコルビン酸活性を有する養魚用
銅相添加物を提供するものである。(Specific Means for Solving the Problems) The present invention provides a copper phase additive for fish farming that is extremely stable in feed and has ascorbic acid activity.
アルコルビン酸要求量は魚種や成育段階により異なる。The amount of ascorbic acid required varies depending on the fish species and growth stage.
ニジマス、アマゴ、アユ、マダイ、ハマチなどはアスコ
ルビン酸欠乏症による変形魚が発生する場合が多い。ま
た、ビタミン類は摂取したタンパク質を始めとする各種
栄養素の正常な代謝に必要であり、一般に代謝の盛んな
若齢期にその要求性が高いが、アスコルビン酸は仔稚魚
期における骨格形成に必要な結合組織コラーケ゛ンの生
合成にとって必須である。さらに、ふ化後からアスコル
ビン酸を含む飼料を摂取する丑での間は産卵前の卵のア
スコルビン酸含有量がふ化した仔魚の正常な骨格形成因
子となるため、仔稚魚用飼料、親魚用飼料ともにアスコ
ルビン酸の重要性が強調される。Rainbow trout, amago, sweetfish, red sea bream, yellowtail, etc. often develop deformed fish due to ascorbic acid deficiency. In addition, vitamins are necessary for the normal metabolism of various nutrients including ingested proteins, and are generally required at a high rate during young stages when metabolism is active, while ascorbic acid is necessary for skeletal formation during the larval stage. It is essential for the biosynthesis of connective tissue collagen. Furthermore, during the period when oxen consume feed containing ascorbic acid after hatching, the ascorbic acid content of the eggs before spawning becomes a factor for normal skeletal formation of hatched larvae, so both feed for larvae and feed for parent fish are The importance of ascorbic acid is emphasized.
本発明のＬ−アルコルビン酸−２−リン酸エステルまた
はその塩は例えば二ソマス稚魚の場合には飼料］、 ｋ
ｇあたり２ミリモル以」＝添加されればコラーケゝンの
代謝異常に基づく変形魚の発生を予防することができ、
負傷、細菌感染にも充分対応できるよってなる。Ｌ−ア
スコルビン酸−２−ＩＪ ７酸エステルまたはその塩は
いずれも魚体内の酵素によ！１ｌＬ−アスコルビン酸と
なり、アスコルビン酸活性を発揮する。The L-alcorbic acid-2-phosphate ester or its salt of the present invention is used as a feed for juvenile Nisomass fish], k
2 mmol or more per gram = if added, it can prevent the occurrence of deformed fish due to metabolic abnormalities in collah cane,
It can also be used to deal with injuries and bacterial infections. Both L-ascorbic acid-2-IJ 7-acid ester and its salts are produced by enzymes in the fish body! It becomes 1lL-ascorbic acid and exhibits ascorbic acid activity.
次に実施例を挙げて、本発明をさらに具体的に説明する
が本発明はこれにより制限されるものではない。Next, the present invention will be explained in more detail with reference to Examples, but the present invention is not limited thereto.
実施例
白魚粉５５係、α−ポテトスターチ３２係、大豆油５％
、マノクコラム塩３係、アスコルビン酸を含まないビタ
ミン混合物５係からなるベレット飼料（基本飼料）を調
製し、これをアスコルビン酸欠２区飼料とした。この基
本飼料成分］、 ｋ１７にさらにアスコルビン酸の２ミ
リモルを加えて調製したものをアスコルビン酸添加区飼
料、また基本飼料成分１ ｋｇに本発明化合物中のＬ−
アスコルビン酸−２−リン酸エステルマグネシウム塩の
２ミリモルを加えて調製したものを本発明化合物添加区
飼料とした。但し、ビタミン混合物５↓には塩酸チアミ
ン（、ｍ９、リボフラビン２０ｍ９、塩酸ピリドキシン
４■、ビタミンＢ１２０００９ｍ９、ニコチン酸８０ｍ
９、塩化クロリン８００ ｍ９、イノシトール４００
ｍ９、パントテン酸カルシウム２８ｍｇ、ビオチン０．
６ ｍ９、葉酸］、、 ５ ｍｇ、α−トコフェノール
４（１９、メマデイオン４■、カルシフェロール０．０
５ｍり、酢酸レチネン２０ｍ９、セルローズ３５９６ｍ
９を含む。以上のベレット飼料をニジマスの浮上稚魚に
飽食量を給餌し、１００日間飼育した。各試験区あたり
２００尾を飼育し、給餌回数は給餌開始００〜８０日後
が］日６回、８１〜１００日後が１日４回とした。飼料
は給餌開始の５０日前に調製したものを使用した。経時
的に各区のニジマス稚魚の平均体重を調査した。また、
各区の生存屋敷、変形屋敷を経時的に調査し、表１に示
した。Example White fish meal 55 parts, α-potato starch 32 parts, soybean oil 5%
A beret feed (basic feed) consisting of 3 parts of manok column salt and 5 parts of a vitamin mixture not containing ascorbic acid was prepared, and this was used as the ascorbic acid-deficient 2nd group feed. This basic feed ingredient], K17 was prepared by adding 2 mmol of ascorbic acid to the ascorbic acid-added diet, and 1 kg of the basic feed ingredient was added with L- in the compound of the present invention.
Feed containing the compound of the present invention was prepared by adding 2 mmol of ascorbic acid-2-phosphate magnesium salt. However, vitamin mixture 5↓ contains thiamine hydrochloride (,m9, riboflavin 20m9, pyridoxine hydrochloride 4■, vitamin B120009m9, nicotinic acid 80m9).
9, Chlorine chloride 800 m9, Inositol 400
m9, calcium pantothenate 28mg, biotin 0.
6 m9, folic acid], 5 mg, α-tocopherol 4 (19, memadeion 4), calciferol 0.0
5m, retinene acetate 20m9, cellulose 3596m
Contains 9. The above pellet feed was fed to a satiated amount to floating juvenile rainbow trout, and the fish were raised for 100 days. 200 fish were raised in each test plot, and the number of feedings was 6 times a day from 00 to 80 days after the start of feeding, and 4 times a day from 81 to 100 days after the start of feeding. The feed used was prepared 50 days before the start of feeding. The average weight of juvenile rainbow trout in each area was investigated over time. Also,
Surviving mansions and transformed mansions in each ward were investigated over time and are shown in Table 1.
その結果、平均体重（Ｃ区間の差はほとんどなかった。As a result, there was almost no difference in average body weight (C section).
しかし、アスコルビン酸欠乏区と比べ、アスコルビン酸
類添加区では変形魚の出現数、死亡率が低下し、特にＬ
−アスコルビン酸−２−リン酸エステルマグネシウム塩
を添加した区では変形屋敷の出現を完全に抑えた。However, compared to the ascorbic acid-deficient area, the number of deformed fish and mortality rate decreased in the ascorbic acid-added area, especially L.
-The appearance of deformed mansions was completely suppressed in the plots to which ascorbic acid-2-phosphate ester magnesium salt was added.
Claims (1)
ルまたはその塩類を含有することを特徴とする養魚飼料
用添加物。An additive for fish feed, characterized in that it contains L-ascorbic acid-2-phosphate or its salts as an active ingredient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61016739A JPH0693821B2 (en) | 1986-01-30 | 1986-01-30 | Additives for fish feed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61016739A JPH0693821B2 (en) | 1986-01-30 | 1986-01-30 | Additives for fish feed |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10011455A Division JP2943785B2 (en) | 1998-01-23 | 1998-01-23 | Additives for fish farm powder feed and feed for fish farm |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62175142A true JPS62175142A (en) | 1987-07-31 |
| JPH0693821B2 JPH0693821B2 (en) | 1994-11-24 |
Family
ID=11924634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61016739A Expired - Lifetime JPH0693821B2 (en) | 1986-01-30 | 1986-01-30 | Additives for fish feed |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0693821B2 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2257628A (en) * | 1991-06-20 | 1993-01-20 | Martin Richard Jaffa | Vitamin pill for fish |
| WO1998034474A1 (en) * | 1997-02-07 | 1998-08-13 | K.I Chemical Industry Co., Ltd. | Process of enhancing growth and survival of aquatic organisms through water borne enrichment with stable vitamin c derivatives |
| EP1046345A3 (en) * | 1999-04-23 | 2002-07-10 | Showa Denko Kabushiki Kaisha | Preparation for administration to animals and feeding method thereof |
| CN105146077A (en) * | 2015-08-05 | 2015-12-16 | 贾红琴 | Chinese herbal medicine additive for aquaculture and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4924783A (en) * | 1972-06-29 | 1974-03-05 | ||
| JPS52102192A (en) * | 1976-02-24 | 1977-08-26 | Nippon Chemiphar Co | Feed for fish farming containing ascorbtc acidd22 sulphate |
| JPS52136160A (en) * | 1976-05-06 | 1977-11-14 | Univ Kansas State | Preparation of phosphoric ester of ascorbic acid |
-
1986
- 1986-01-30 JP JP61016739A patent/JPH0693821B2/en not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4924783A (en) * | 1972-06-29 | 1974-03-05 | ||
| JPS52102192A (en) * | 1976-02-24 | 1977-08-26 | Nippon Chemiphar Co | Feed for fish farming containing ascorbtc acidd22 sulphate |
| JPS52136160A (en) * | 1976-05-06 | 1977-11-14 | Univ Kansas State | Preparation of phosphoric ester of ascorbic acid |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2257628A (en) * | 1991-06-20 | 1993-01-20 | Martin Richard Jaffa | Vitamin pill for fish |
| WO1998034474A1 (en) * | 1997-02-07 | 1998-08-13 | K.I Chemical Industry Co., Ltd. | Process of enhancing growth and survival of aquatic organisms through water borne enrichment with stable vitamin c derivatives |
| EP1046345A3 (en) * | 1999-04-23 | 2002-07-10 | Showa Denko Kabushiki Kaisha | Preparation for administration to animals and feeding method thereof |
| CN105146077A (en) * | 2015-08-05 | 2015-12-16 | 贾红琴 | Chinese herbal medicine additive for aquaculture and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0693821B2 (en) | 1994-11-24 |
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| Date | Code | Title | Description |
|---|---|---|---|
| RVTR | Cancellation due to determination of trial for invalidation |