JPS62151498A - Cleanser - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to a cleaning agent that is particularly effective in removing tar from cigarettes.

In general, oral compositions such as toothpaste and glophyllakis paste are used as a tooth cleaning base to efficiently remove stains, grains, food particles, etc. that have adhered to or deposited on the teeth by physical action. Contains abrasives, but
In order to effectively remove these stains, it is desirable that the abrasive has a high abrasive power. In particular, smokers' teeth are heavily caked with cigarette tar, and it is necessary to use a highly abrasive abrasive to remove such cigarette tar.

However, the higher the abrasive power of the abrasive, the more likely it is to abrade and damage the tooth surface, and there is a risk of tooth wear. Conversely, if the polishing power is lowered in order to avoid damage to the teeth, there is a problem in that the cleaning power also decreases. In addition, cigarette tar that has adhered or settled on the teeth can be removed to some extent by brushing the tooth surface with a toothbrush, but areas that the toothbrush cannot reach cannot be cleaned, so brushing with abrasives, etc. It is desired to clean teeth without relying on physical action, and for this reason, active ingredients have been proposed that use chemical action to remove the adhesion and deposits of cigarette tar on teeth. An active ingredient with a high tar removal effect is desired.

The present invention was made in response to the above-mentioned needs, and an object of the present invention is to provide a cleaning agent that is highly effective in removing tar from cigarettes.

Means and Action for Solving the Problems The present inventors conducted intensive studies to achieve the above object and found that 2-octatool is uniquely effective in removing tar from cigarettes. .

In other words, as shown in Experiment 1, which will be described later, lower alcohols such as ethanol, which contain almost no water and are highly concentrated or highly purified, dissolve tobacco tar well and have an excellent tar remover effect on their own. However, when used at low concentrations by mixing with water or blending into oral compositions such as toothpaste, it shows almost no tar removal effect. In addition, even though alcohols with carbon atoms of 5 or more that are poorly soluble or insoluble in water do not have sufficient tar removal effects at low concentrations, only 2-octatool, an isomer of octatool with 8 carbon atoms, is outside the i range. Even when used in low concentrations, 2-Octatool is highly effective in completely removing cigarette tar, and therefore 2-Octatool has a unique effect as an active tar remover ingredient incorporated into oral compositions, etc. This is the heading that led to the present invention.

The present invention will be explained in more detail below.

The cleaning agent according to the present invention contains 2-octatool as an active ingredient for removing cigarette tar, and e)
The cleaning agent of the present invention can be used in oral compositions such as toothpastes, mouth rinses, and gums to remove cigarette tar from teeth, and as a filler for cigarette filters and as a tar remover for i4ve. It is used as a disinfectant to remove tar from cigarettes and to clean them. Furthermore, by incorporating it into liquid detergents and soaps, it is highly effective in cleaning cigarette-stained clothes, ashtrays, hands, and feet. In particular, when all 2-OctaTool is added to the toothpaste, stains on the teeth can be removed by the chemical action of 2-OctaTool rather than the physical action of an abrasive, so it is possible to remove stains from the teeth by the chemical action of the 2-OctaTool without using the physical action of an abrasive. The amount of abrasive can be reduced or an abrasive with low abrasive power can be used, resulting in a toothpaste with a high cleaning method that has significantly reduced abrasiveness to the teeth, achieving low abrasiveness and high cleaning. be able to.

Here, the blending amount of 2-octatool varies depending on the type of cleaning agent, etc., but when used as an oral composition, 0.
．． 01 to 10% (weight i%, same below), especially 0.05 to 10%
The content is preferably 3%, and as a tar remover such as Chibu, it is preferably 1 to 100%, particularly 5 to 50%.

The cleaning agent of the present invention may contain appropriate components depending on the type of cleaning agent, if necessary.

For example, when used as a toothpaste, calcium hydrogen phosphate dihydrate and anhydride, calcium carbonate, calcium pyrophosphate, calcium sulfate, insoluble sodium metaphosphate, silica, aluminosilicate, aluminum hydroxide, aluminum oxide, resin Abrasives such as (compounding amount usually 20-60%), binders such as sodium carboxymethyl cellulose, hydroxyethyl cellulose, sodium alginate, caradanan, gum arabic, xanthan gum, polyvinyl alcohol (0.3-5%),
polyethylene glycol, sorbitol, glycerin,
Thickening agents such as propylene glycol (10-70 g), sodium lauryl sulfate, sodium dodecylbenzenesulfonate, hydrogenated coconut fatty acid monoglyceride monosulfate, sodium lauryl sulfoacetate, N
- Surfactants (0-5%) such as sodium lauroyldercosinate, N-acylglutamate, laurylgetanolamide, sucrose fatty acid ester, as well as sodium saccharin, stevioside, neoheschili'dildihydrochalcone, glycyrrhizin, perillartine,
Sweeteners such as p-methoxycinnamic aldehyde and thaumatin, fragrances, preservatives, and various active ingredients may be added.

In addition, 2-octatool hardly mixes with water, so
When it is mixed with water and dissolved, it is preferable to add an active agent as appropriate. Furthermore, when 2-octatool is used in combination with ethanol, the tar removal effect is synergistically improved, so it is preferable to include ethanol.

Effects of the Invention The cleaning agent of the present invention is extremely effective in removing tobacco tar because it contains all of 2-octatool.

Next, the effects of the present invention will be specifically explained using experimental examples.

[Experimental Example 1] The cleaning power of water-soluble aliphatic alcohols and their aqueous solutions was evaluated by the following method. The results are shown in Table 1.

Cleaning power evaluation method Cigarette key 4 - collected in the usual way, 1.5c! ! Apply evenly on one corner of the tile. This is about 130-140
After drying by heating at °C for a day and night, the tiles were set in a polishing container and brushed with a sample (151d) under a load of 200y. After polishing, the removal rate of tobacco tar from the tiles was evaluated with the naked eye.

Note that the number of times of pushing differs depending on the loft of the tar, so polishing that achieves a tar removal rate of approximately 6 for the internal standard t-carbin (1% + 1% sodium lauryl sulfate aqueous dispersion, the same applies hereinafter) The number of times was set each time.

- Calvin is 6.0.3 - Octatool is 4.5, peppermint oil is 2.0°, water is the standard of 00, and the evaluation of the sample is by creating a calibration curve from the experimental values and standard values of these internal standards. Calculated.

In addition, as a brushing brush, there are 44 tufts of hair,
The material used was nylon (62) with a hair thickness of 8 mils (approximately 0.2 cm) and a hair length of 120 mm, and the hardness of the material was M according to the Household Goods Quality Indication Law.

Evaluation criteria score 1: Tobacco tar removal rate 0-10% 2:
l/ IQ~203: /'
20-304: /7 30-4
05: #40-506:
l 50-607: II
60-708: 1 70-80 9: 〃 80-90 10: If 90-100 Table 1 [Experiment Example 2] Experiments were carried out on samples in which % of poorly soluble aliphatic alcohol was solubilized with 1% sodium lauryl sulfate. The cleaning power was evaluated using the evaluation method in Example 1. The results are shown in Table 2.

According to the results in Table 2, Table 1.2, lower alcohols are highly effective in removing tar from cigarettes when they contain almost no water, but they are not as effective when used as a 10% aqueous solution. Alcohols with carbon numbers of 5 or more had a low tar removal effect at a concentration of 1%, but 2-
Only Octa Tool has a uniquely high tar removal effect,
Recognized for its excellent cleaning ability.

[Experimental Example 3] The stain removal and inhibition effects of toothpaste containing 2-octatool were investigated by the method shown below.

Experimental Method Four healthy people (male, smokers) were selected and tested using the toothpastes shown in Table 3 (Al: inventive toothpaste, &2: comparative toothpaste) for one month each. Scaling was performed two weeks before the start of the test, and only brushing was performed until the start of the test. The amount of tooth brushing is about 2/3 of the length of the hair bundle.
The subjects were asked to brush their teeth three times a day, and no specific instructions were given on how to brush. Photographs were taken twice, before the start of the test and 4 weeks after the start of the test, and the degree of stain adhesion was evaluated using the following method.

In addition, in the formulation, hydrated silicic acid is used as a filler and thickener, and has almost no abrasive or abrasive power. By the way, the RDA value (dentin abrasion value) of both toothpastes is about 15, which is about the same as brushing.

Stine's evaluation method: A transparent glass film with a 3.5-square grid drawn on it was placed over the photo, and the squares with dirt were counted and used as Stine's score.

The evaluation site was 3-3 maxillary and labial surfaces, a total of 12 teeth.

The results are shown in Table 4.

The results in Table 3 and Table 4 show that the toothpaste of the present invention containing 2-octatool is superior in stain removal and prevention effects compared to the comparative toothpaste.

Examples will be shown below, but the present invention is not limited to the following examples.

[Example 1'3 # Toothpaste calcium hydrogen phosphate dihydrate 45.
0% Glycerin 10.0 Sorbitol 25.0 Carboquine Methylcellulose Sodium 0.5
Veegum 0.2 Carrageenan 0.3% Sankarin Sodium 0.2 Sodium Lauryl Sulfate 1.2 Fragrance
1.0 Preservative Trace amount 2-octatool 0.3 [Example 2] Toothpaste abrasive silicon dioxide 10.0 Propylene glycol 2.0 Sorbitol 20.0 Sodium carboxymethylcellulose 1.4 Sodium succalin 0.1 Lauryl sulfate Sodium 1.5 α-Alumina Anhydride 3.0 Colloidal Silica
3.0 Fragrance 1.0 Preservative 2-Octatool 1.0 [Example 3] Toothpaste Aluminum Hydroxide 18.0 Thipropylene Glycol 2.0 Glycerin 25. .

Hydroxyethyl cellulose 1
．． 2 Satucalin sodium 0.
1 Sodium Lauric Sulfate 1.0
Lauroyl diethanolamide o, 8 colloidal silica 3.0 fragrance
1.0 Sodium monofluorophosphate 0.76 Antiseptic set Trace amount 2-octatool 1.0 Water
Remaining amount
100.01y [Example 4] Mouthwash ethanol 5.0% Sodium saccharin 0.05 Sodium monofluorophosphate 0.05 Chlorhexidine gluconate 0.005 Lauryl ethanolamide 0.4 Colorant
Appropriate amount of preservative
〃Australianization stopper
〃Fragrance 1.0 2-octatool 3.0 Water
Remaining [Example 5] Chewing gum Gum base 40. Ots carbonated lucium 2.0 starch syrup
15.0 powder shield
40. Qbe Gumint Oil 0.2 Dextranase
0.12-octatool
1.0 water
Residue [Example 6] - 9 Tar remover Calcium carbonate 6° Sodium dodecylbenzenesulfonate 52-octatool 30100% Use a cotton swab etc. soaked in a small amount of the tar remover of the above formulation.

[Example 7] Liquid detergent monoethanolamine 5 polyoxyethylene alkyl phenol ether 3 sodium sulfonate 22-octatool 1° ethanol
3 Fragrance 1 100%

Claims (1)

[Claims] A cleaning agent characterized by containing 1,2-octanol.