JPS6213952B2 - - Google Patents

Info

Publication number
JPS6213952B2
JPS6213952B2 JP55063877A JP6387780A JPS6213952B2 JP S6213952 B2 JPS6213952 B2 JP S6213952B2 JP 55063877 A JP55063877 A JP 55063877A JP 6387780 A JP6387780 A JP 6387780A JP S6213952 B2 JPS6213952 B2 JP S6213952B2
Authority
JP
Japan
Prior art keywords
group
compound according
oxo
benzimidazoline
ethyl ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55063877A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55153772A (en
Inventor
Saajesu Reinhaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Original Assignee
PFIZER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER filed Critical PFIZER
Publication of JPS55153772A publication Critical patent/JPS55153772A/ja
Publication of JPS6213952B2 publication Critical patent/JPS6213952B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP6387780A 1979-05-16 1980-05-14 33*substituted methyl**22oxoo11 benzimidazolinealkanoic acid compound and its derivative Granted JPS55153772A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/039,264 US4209527A (en) 1979-05-16 1979-05-16 Benzimidazolone derivatives

Publications (2)

Publication Number Publication Date
JPS55153772A JPS55153772A (en) 1980-11-29
JPS6213952B2 true JPS6213952B2 (https=) 1987-03-30

Family

ID=21904541

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6387780A Granted JPS55153772A (en) 1979-05-16 1980-05-14 33*substituted methyl**22oxoo11 benzimidazolinealkanoic acid compound and its derivative

Country Status (7)

Country Link
US (1) US4209527A (https=)
EP (1) EP0019440B1 (https=)
JP (1) JPS55153772A (https=)
DE (1) DE3060894D1 (https=)
DK (1) DK151957C (https=)
GR (1) GR68210B (https=)
IE (1) IE49800B1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307108A (en) * 1979-12-26 1981-12-22 Pfizer Inc. Method for lowering sorbitol levels using spiro-imides
DE3042481A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln (omega)-(2-oxo-benzazolinyl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4960785A (en) * 1988-12-16 1990-10-02 Pfizer Inc. Indolinone derivatives
US4940708A (en) * 1986-10-30 1990-07-10 Pfizer Inc. 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts
WO1993013092A1 (en) * 1986-11-24 1993-07-08 Reinhard Sarges Imidazolidinedione derivatives
US5064852A (en) * 1988-12-16 1991-11-12 Pfizer Inc. Indolinone derivatives
US4996204A (en) * 1989-05-11 1991-02-26 Pfizer Inc. Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors
FR2722190B1 (fr) * 1994-07-05 1996-10-04 Sanofi Sa Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
WO2008147697A1 (en) * 2007-05-22 2008-12-04 Boehringer Ingelheim International Gmbh Benzimidazolone chymase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA928296A (en) * 1967-06-05 1973-06-12 Umio Suminori N-substituted and n, n-disubstituted aminocarbonylalkyl compounds and their production
FR1574588A (https=) * 1968-07-26 1969-07-11
JPS5214413B2 (https=) * 1971-08-19 1977-04-21
JPS4828916A (https=) * 1971-08-21 1973-04-17
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4161603A (en) * 1976-05-12 1979-07-17 Ciba-Geigy Corporation Dicarboxylic acids and dicarboxylic acid esters containing a benzimidazolone radical

Also Published As

Publication number Publication date
JPS55153772A (en) 1980-11-29
US4209527A (en) 1980-06-24
DE3060894D1 (en) 1982-11-11
DK151957C (da) 1988-08-08
EP0019440A1 (en) 1980-11-26
DK210580A (da) 1980-11-17
EP0019440B1 (en) 1982-09-29
GR68210B (https=) 1981-11-12
IE801005L (en) 1980-11-16
IE49800B1 (en) 1985-12-25
DK151957B (da) 1988-01-18

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