JPS6155882B2 - - Google Patents
Info
- Publication number
- JPS6155882B2 JPS6155882B2 JP5659383A JP5659383A JPS6155882B2 JP S6155882 B2 JPS6155882 B2 JP S6155882B2 JP 5659383 A JP5659383 A JP 5659383A JP 5659383 A JP5659383 A JP 5659383A JP S6155882 B2 JPS6155882 B2 JP S6155882B2
- Authority
- JP
- Japan
- Prior art keywords
- organ
- container
- temperature
- refrigerant
- perfusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000000056 organ Anatomy 0.000 claims description 54
- 230000010412 perfusion Effects 0.000 claims description 36
- 239000007788 liquid Substances 0.000 claims description 22
- 238000007710 freezing Methods 0.000 claims description 21
- 230000008014 freezing Effects 0.000 claims description 19
- 238000010257 thawing Methods 0.000 claims description 17
- 239000003507 refrigerant Substances 0.000 claims description 16
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 14
- 239000012530 fluid Substances 0.000 claims description 11
- 239000003795 chemical substances by application Substances 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000008280 blood Substances 0.000 claims description 9
- 210000004369 blood Anatomy 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 210000001367 artery Anatomy 0.000 claims description 7
- 210000003240 portal vein Anatomy 0.000 claims description 7
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 210000003462 vein Anatomy 0.000 claims description 4
- 239000002577 cryoprotective agent Substances 0.000 claims description 3
- 210000001835 viscera Anatomy 0.000 claims 1
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 description 11
- 238000000034 method Methods 0.000 description 11
- 239000000243 solution Substances 0.000 description 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 7
- 238000002054 transplantation Methods 0.000 description 5
- 239000007798 antifreeze agent Substances 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 238000004321 preservation Methods 0.000 description 4
- 230000002528 anti-freeze Effects 0.000 description 3
- 230000036760 body temperature Effects 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 230000008081 blood perfusion Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000002262 irrigation Effects 0.000 description 2
- 238000003973 irrigation Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000002595 cold damage Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N methyl monoether Natural products COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5659383A JPS59184101A (ja) | 1983-03-31 | 1983-03-31 | 臓器の保存解凍用装置 |
| DE8383303133T DE3366419D1 (en) | 1982-06-04 | 1983-06-01 | Method of preserving organ and apparatus for preserving the same |
| CA000429420A CA1200507A (en) | 1982-06-04 | 1983-06-01 | Method of preserving organ and apparatus for preserving the same |
| EP83303133A EP0096997B1 (en) | 1982-06-04 | 1983-06-01 | Method of preserving organ and apparatus for preserving the same |
| US06/615,212 US4494385A (en) | 1982-06-04 | 1984-05-20 | Method of preserving organ and apparatus for preserving the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5659383A JPS59184101A (ja) | 1983-03-31 | 1983-03-31 | 臓器の保存解凍用装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59184101A JPS59184101A (ja) | 1984-10-19 |
| JPS6155882B2 true JPS6155882B2 (en, 2012) | 1986-11-29 |
Family
ID=13031491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5659383A Granted JPS59184101A (ja) | 1982-06-04 | 1983-03-31 | 臓器の保存解凍用装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59184101A (en, 2012) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH035702A (ja) * | 1989-06-01 | 1991-01-11 | Canon Inc | 貼り合わせレンズ等及びその製造方法 |
-
1983
- 1983-03-31 JP JP5659383A patent/JPS59184101A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59184101A (ja) | 1984-10-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4494385A (en) | Method of preserving organ and apparatus for preserving the same | |
| US4462215A (en) | Method of preserving organ and apparatus for preserving the same | |
| US4688387A (en) | Method for preservation and storage of viable biological materials at cryogenic temperatures | |
| JP2004503473A (ja) | 高温凍結を使用した生物活性材料の低温保存 | |
| Hunt et al. | Fractures in cryopreserved arteries | |
| CA1217350A (en) | Apparatus for freezing fertilized ova, spermatozoa or the like | |
| US20100233670A1 (en) | Frozen Viable Solid Organs and Method for Freezing Same | |
| US20080008987A1 (en) | Laparoscopic kidney cooling device | |
| EP2308295A3 (en) | Apparatus for transporting an organ | |
| CN113749753B (zh) | 一种压力调节方法、装置及冷冻手术系统 | |
| AU2015302253B2 (en) | All-liquid cryoablation catheter | |
| JPS6156202B2 (en, 2012) | ||
| JPS6155882B2 (en, 2012) | ||
| JPS6156201B2 (en, 2012) | ||
| WO2006083674A2 (en) | Warming gradient control for a cryoablation applicator | |
| JPS6155881B2 (en, 2012) | ||
| JP2632531B2 (ja) | 臓器の保存方法 | |
| Schimmel et al. | Freezing of whole rat and dog kidney by perfusion of liquid nitrogen through the renal artery | |
| CN117398172A (zh) | 一种冷冻消融仪的控制方法 | |
| JP3239418B2 (ja) | 生体臓器保存再生方法およびその装置 | |
| RU2268590C1 (ru) | Способ криоконсервации органов и тканей in situ | |
| JPS6061502A (ja) | 臓器保存処理のための潅流方法と潅流装置 | |
| Webb et al. | Hypothermic organ preservation: comparison of cooling and warming methods | |
| WO2003051111A2 (en) | Cryopreservation of biological materials using pre-chilled protectant | |
| SU1097875A1 (ru) | Устройство дл замораживани живых биологических объектов в контейнерах |