JPS61501629A - 放射性標識化リポタンパク及びその製造法 - Google Patents

放射性標識化リポタンパク及びその製造法

Info

Publication number
JPS61501629A
JPS61501629A JP60501441A JP50144185A JPS61501629A JP S61501629 A JPS61501629 A JP S61501629A JP 60501441 A JP60501441 A JP 60501441A JP 50144185 A JP50144185 A JP 50144185A JP S61501629 A JPS61501629 A JP S61501629A
Authority
JP
Japan
Prior art keywords
technetium
dtpa
protein
ldl
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60501441A
Other languages
English (en)
Japanese (ja)
Inventor
リ−ス　ロバ−ト　エス
Original Assignee
マサチユ−セツツ　インステイテユ−ト　オブ　テクノロジ−
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マサチユ−セツツ　インステイテユ−ト　オブ　テクノロジ− filed Critical マサチユ−セツツ　インステイテユ−ト　オブ　テクノロジ−
Publication of JPS61501629A publication Critical patent/JPS61501629A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A61K51/1224—Lipoprotein vesicles, e.g. HDL and LDL proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP60501441A 1984-03-28 1985-03-27 放射性標識化リポタンパク及びその製造法 Pending JPS61501629A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/594,244 US4647445A (en) 1984-03-28 1984-03-28 Radiolabelled lipoproteins and method for making same
US594244 1984-03-28

Publications (1)

Publication Number Publication Date
JPS61501629A true JPS61501629A (ja) 1986-08-07

Family

ID=24378117

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60501441A Pending JPS61501629A (ja) 1984-03-28 1985-03-27 放射性標識化リポタンパク及びその製造法

Country Status (6)

Country Link
US (1) US4647445A (https=)
EP (1) EP0176562A4 (https=)
JP (1) JPS61501629A (https=)
CA (1) CA1249513A (https=)
GR (1) GR850788B (https=)
WO (1) WO1985004329A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937067A (en) * 1984-12-13 1990-06-26 Massachusetts Institute Of Technology Method and means for detection of adrenal metabolic activity
AU8152887A (en) * 1986-10-17 1988-05-06 Cytogen Corporation Method for preparation of protein-chelator-metal ion compositions suitable for injection
CA1285223C (en) * 1986-11-10 1991-06-25 New England Deaconess Hospital Detection of vascular disease
US4877599A (en) * 1986-11-10 1989-10-31 New England Deaconess Hospital Corporation Detection of vascular disease with labelled antibodies
US5164175A (en) * 1986-12-10 1992-11-17 Hoechst Aktiengesellschaft Diagnostic aid containing an organ-specific substance labeled with technetium-99m
US4871836A (en) * 1987-10-13 1989-10-03 E. R. Squibb & Sons, Inc. Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes
US4917878A (en) * 1988-05-02 1990-04-17 Thomas Jefferson University Novel use of a radiolabelled antibody against stage specific embryonic antigen for the detection of occult abscesses in mammals
US5726153A (en) * 1988-05-02 1998-03-10 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5972890A (en) * 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
CA1340977C (en) * 1988-11-15 2000-04-25 Monty Krieger Scavenger receptor protein and antibody thereto
US5078985A (en) * 1989-08-09 1992-01-07 Rhomed, Incorporated Radiolabeling antibodies and other proteins with technetium or rhenium by regulated reduction
CA2065299C (en) * 1989-08-09 2001-07-24 Buck A. Rhodes Direct radiolabeling of antibodies and other proteins with technetium or rhenium
WO1994005308A1 (en) * 1992-08-28 1994-03-17 Magainin Pharmaceuticals Inc. Purification of amphiphilic compounds
US6080384A (en) * 1997-03-25 2000-06-27 American Biogenetic Sciences, Inc. Methods for radionuclide-labeling of biomolecules and kits utilizing the same
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses
US6782289B1 (en) 1999-10-08 2004-08-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and apparatus for characterizing lesions in blood vessels and other body lumens
WO2001049162A2 (en) * 2000-01-04 2001-07-12 Imetrx, Inc. Intravascular imaging detector
US20030152513A1 (en) * 2001-09-06 2003-08-14 Imetrix, Inc. Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector
US7651506B2 (en) * 2003-10-02 2010-01-26 University Of Florida Research Foundation, Inc. Frameless stereotactic guidance of medical procedures
US8097283B2 (en) 2004-01-15 2012-01-17 Mount Sinai School Of Medicine Methods and compositions for imaging
US7874975B2 (en) * 2005-07-20 2011-01-25 Clear Vascular, Inc. Methods and compositions for treating luminal inflammatory disease
US9623129B2 (en) * 2005-09-26 2017-04-18 Snip Holdings, Inc. Methods and therapies for treating inflammatory conditions with exposed collagen
US8361494B2 (en) * 2006-03-10 2013-01-29 The Trustees Of The University Of Pennsylvania Biomimetic iron-oxide-containing lipoprotein and related materials
EP2382466B1 (en) 2008-12-30 2016-03-09 Children's Medical Center Corporation Method of predicting acute appendicitis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364920A (en) * 1975-04-30 1982-12-21 Medi-Physics, Inc. Stable diagnostic reagents
US4057617A (en) * 1975-05-15 1977-11-08 Abramovici J Method of labeling proteins with technetium
US4293537A (en) * 1978-09-05 1981-10-06 Wong Dennis W Novel chemical method of labeling proteins with 99m Tc-Technetium at physiological condition
US4424200A (en) * 1979-05-14 1984-01-03 Nuc Med Inc. Method for radiolabeling proteins with technetium-99m
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies

Also Published As

Publication number Publication date
GR850788B (https=) 1985-11-25
US4647445A (en) 1987-03-03
EP0176562A4 (en) 1986-08-21
CA1249513A (en) 1989-01-31
WO1985004329A1 (en) 1985-10-10
EP0176562A1 (en) 1986-04-09

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