JPS6143104A - Hair tonic - Google Patents

Abstract

PURPOSE:A hair tonic, having excellent hair-growing and hair-rearing effect, by imparting a humectant property to hairs and head skins to make them in good health together with enhancing and normalizing functions of the hair and scalp, and containing a hyaluronic acid-protein complex and an essence of placenta as necessary ingradients. CONSTITUTION:A hair tonic containing (A) a hyaluronic acid-protein complex and (B) an essence of placenta as necessary ingredients in a ratio of A=0.01- 10wt% and B=0.001-3wt%. Said hair tonic remarkably enhances the hair tonic and hair-growing effect on the hair and scalp by synergistic effect of such as an excellent cellactivating action and a humectant property of the above-mentioned components (A) and (B). The component (A) is an essence or a powder prepared from an umbilical cord, a cockscomb, an animal skin, a vitreous body, etc., by washing with water, pulverizing into small pieces, and extracting and refining without subjecting to enzymatic decomposition. As for the component (B), the one obtained from a placenta of human, cow, pig, sheep, etc. by the conventional method can be used.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention relates to a novel hair nourishing agent containing a hyaluronic acid-protein complex and a placenta extract as essential components.

In other words, the object of the present invention is to provide a hair nourishing agent that has an excellent hair nourishing effect that improves and normalizes the functions of the hair and scalp, and also provides moisturizing properties to the hair and scalp, making them healthy. It is about providing.

[Prior Art] Various hair tonics have been conventionally used for the prevention and treatment of alopecia. There are various symptoms of alopecia, and the causes and mechanisms of hair loss are still largely unknown. When alopecia is viewed comprehensively, some kind of abnormality is recognized in the area. Therefore, hair tonics include various drugs that have the effect of preventing or suppressing these, such as keratolytic agents that act on the keratin and epidermal system, thinning agents, and anti-inflammatory agents such as salicylic acid, resorcinol, and glycyrrhizinic acid, as well as hair growth agents. Mononitroguaiacol, a cell activation agent that acts on mother cells and the surrounding environment system, pantothenic acid derivatives, female hormones, amino acids, etc., as well as carpronium chloride, a peripheral vasodilator and mobilization promoting agent, Oriental japonica extract, Raysogen, and vitamin E. etc. are mixed. Therefore, the hair tonic is
When used externally, they exert their effectiveness by preventing or suppressing dandruff, itching, and hair loss, and by promoting hair growth and growth, but they have not yet been fully satisfactory.

By the way, placenta extract has an activation effect on the cortical layer and is used as a skin treatment agent in terms of promoting wound repair.
It is used for cuts, burns, etc., and is also used for cosmetic purposes such as treating pigmentation such as spots and freckles, preventing skin aging, and preventing rough skin. In addition, when applied to the hair and scalp, it activates the cellular functions of the scalp and hair roots and harmonizes the functions, correcting the flow of keratin on the scalp and promoting hair growth [Or
, Kurt Richter GmbH: Kosm-
Parf-Drag-Rundschau Nr, 7
-8, 115-11B (1959)].

On the other hand, hyaluronic acid has been researched to be incorporated into cosmetics from the viewpoint of skin protection by taking advantage of its excellent water-retaining ability, and also has the ability to penetrate the skin, stably revitalize tissues, and dilate peripheral blood vessels. to improve blood circulation, stimulate intermediate metabolism, improve the supply of nutrients and excretion of waste products, make skin tissues healthy, improve color and luster, and improve texture (Special Publications Publication No. 33) -500) is publicly known. However, there are not many known examples of the effective use of hyaluronic acid in hair nourishing products based on its cell activating effect and water retention properties.

[Problems to be Solved by the Invention] Various conventional hair nourishing agents are known as described above, but none have been found to be fully satisfactory as they are inferior in substantial hair nourishing and hair growing effects.

Furthermore, placenta extract is also known as one of the important hair growth agents, but when added alone to cosmetics, the hair growth effect is insufficient, and when added in large amounts, it causes stickiness, making it undesirable for use. Ta.

In view of the above-mentioned points, the present invention takes into consideration the fact that the effects of conventional hair nourishing agents are not satisfactory, and attempts to solve the problem.

[Means for Solving the Problems] In order to obtain a hair nourishing agent that has an unprecedented hair nourishing effect, the present inventors conducted intensive research on various hair nourishing agents, and as a result, they discovered that a hyaluronic acid-protein complex and a placenta extract were combined into a hair nourishing agent. They discovered that an extremely excellent hair-nourishing effect can be obtained by using them together, and based on this knowledge, they completed the present invention.

That is, the present invention is characterized by essentially containing a hyaluronic acid-protein complex and a placenta extract, and an object of the present invention is to provide a hair nourishment that is excellent in hair nourishing and hair growth effects.

The configuration of the present invention will be explained below.

Placental extracts essential to the present invention include human, bovine, porcine,
It can be obtained by conventional methods from the placenta of sheep etc.
The extraction method, purification method, and treatment method are not restricted. The amount of placenta extract used in the present invention is 0.01 to 10% by weight, and is effective within this range.

The hyaluronic acid-protein complex that is essential to the present invention is extracted and purified by extracting and purifying the hyaluronic acid-protein complex, which is obtained by washing the tortoise belt, chicken crest, animal skin eyeball glass body, etc. with water and crushing it at low temperature. The blended amount of the hyaluronic acid-protein complex used in the present invention is o,oot~3.
% by weight, and is valid within this range.

By the way, although the hyaluronic acid-protein complex is particularly effective in the hair nourishment of the present invention, prior to the present invention, the effectiveness of various hyaluronic acid-related substances was also studied at the same time.

Hyaluronic acid-related substances are derived from natural products [for example, those disclosed in Japanese Patent Publication No. 33-500, Japanese Patent Publication No. 51-11178, and Japanese Patent Publication No. 58-158798], those extracted by culturing microorganisms, synthetic products, i.e. origin,
There are different extraction methods, purification methods, etc., as well as hyaluronic acid salts such as sodium, potassium, and basic amino acid salts. It has also been found that these also exhibit good hair-nourishing effects when used in combination with placenta extract.

However, in the present invention, when the hyaluronic acid-protein complex is used in combination with placenta extract, it has a more excellent hair-nourishing effect than a hyaluronic acid-free one,
It was the most suitable one.

By using the hyaluronic acid-protein complex and placenta extract in combination as described above, the hair nourishment of the present invention has a synergistic effect on the hair and scalp by the excellent cell activating effect, moisturizing property, etc. of these ingredients. Together with this, it significantly promotes hair nourishing and hair growth effects.

The hair nourishment base material according to the present invention is of various types, such as emulsion, cream, lotion, etc., such as hair tonic, hair liquid, hair lotion, hair cream, hair rinse, shampoo, Sera I lotion, hair spray. , hair products such as hair bags.

Also, as a hair nourishing base, purified water, alcohols, polyhydric alcohols, oils and fats, surfactants, moisturizers, ultraviolet absorbers, thickeners, pigments, preservatives, fragrances, etc. are usually added to cosmetics. Components can be selected and used as appropriate.

In addition, resorcinol, which is a medicinal ingredient in common hair tonics,
Keratolytic agents such as salicylic acid, hormones, vitamin E,
Vitamins such as vitamin B2, amine extracts, herbal medicine extracts such as Oriental japonica extract, photosensitive pigments, bactericides, cooling stimulants such as menthol, etc. can be added as appropriate.

[Example] Next, the present invention will be further explained by giving examples. These do not limit the present invention in any way.

Example [l], Comparative Examples [11 to [3] Hair nourishing agent (hair lotion type) Table 1 shows the formulations of Examples and Comparative Examples.

In addition, the compounding amount is weight%.

(Hereinafter in the margin) Table 1a Hair material (hair lotion type) (Hereinafter in the margin) (Manufacturing method) Example [11] After dissolving (1) to (no in (3)), (4)
〜(()) are sequentially added, stirred and mixed to obtain a hair nourishing agent.

Comparative Examples [11 to [3]] were manufactured according to Example [11], and the hair nourishing effects of Example [1] and Comparative Examples [11 to [3] were used to measure the hair nourishing effect.

The test method is as shown below.

Hair growth effect test method Hartley guinea pig (♀) 1 body weight 500±11.3
The right and left backs of each guinea pig were dehaired, and the right side was used as a control side with no application, and the left side was used as a test side. 11
twice a day.

After coating for 21 days, 20 hairs from both sides were removed and the difference in average hair length between the control side and the test side was examined to examine the effect on the growth of the guinea pig's body length in Example [1]. The results are shown in Table 2.

Table 2 Hair nourishing effect measurement results - 11 uniform growth - (Σ test side body L / 20 - Σ control side body hair /
201 X 1/101-1 Oki I As is clear from the above results, Example [1
] The hair nourishing material showed an extremely superior hair nourishing effect than that of Comparative Example [11]. especially.

Although Comparative Example [1] and Comparative Example [2], which contained hyaluronic acid-Ippaku complex and placenta extract alone in the base, were more effective than Comparative Example [3], hyaluronic acid-protein complex In Example [1], in which the placenta extract was used in combination with the placenta extract, it was found that it had a remarkable effect.

Example [2] Hair nourishing material (hair cream type) (prescription)
(% by weight) (1) Beeswax 1.0 (Li) Liquid paraffin 50.0 (3) Stearic acid 3.0 (4) Sorbitan sesquioleate 2.2 (5) Polyoxyethylene sorbitan monolaurate (20!,0 )
1.8 (Hyaluronic acid-protein complex
0.2 (2) Placenta extract 0
．． 2 (8) Fragrance 0
．． 2 ((t) Methyl paraoxybenzoate 0
．． 10th phrase Purified water remaining amount (manufacturing method) ((to) Mix and dissolve ~(2) and (□□□~(10), then add (1) to (5) mixed and heated and dissolved, Emulsify. After cooling, add (8) to obtain a hair nourishing material.

The hair nourishing material of Example [2] obtained as described above had an extremely excellent hair nourishing effect.

Example [3] Hair nourishing material (hair solid type) (formulation)
(% by weight) (11 Mr, dynamic para 747 15.0 (2 lanolin alcohol 2.1 (3) polyoxyethylene lauryl ether phosphoric acid (12E, O,) 7.0 (
4) Lauric acid jetanolamide 3.0 (5
1 Hyaluronic acid-protein complex 0.5 (equal) Placenta extract 1.0 (η fragrance
Appropriate amount (8) Preservative
Appropriate amount (spring purified water
Remaining amount (manufacturing method)
~(After mixing 4, add the heated and dissolved mixture and emulsify.

After cooling, (7) is added to obtain a hair nourishing material.

The hair-nourishing prickles of Example [3] obtained as described above had an extremely excellent hair-nourishing effect.

Example [4] Hair nourishing material (hair solid type) (formulation)
(% by weight) (1) Polyoxypropylene butyl ether phosphoric acid (35P, 0.)
9.0 (2) Pholioxypropylene heptabutyl ether (80P, 0.) 10.0
(3) Triethanolamine 1.0 (4
) Hyaluronic acid-protein complex 0.5 ((b) Placenta extract 2.0 (phrase) Ethanol 30.0 (7) Fragrance appropriate amount (8) Preservative appropriate amount (9) Purified water
Remaining amount (manufacturing method) (4) to (5) (after dissolving in odor, add (1) to (3) to this)
A mixed and dissolved mixture of ((to) to (8)) is added, and the mixture is stirred and mixed to obtain a hair nourishing material.

The hair nourishing agent of Example [4] obtained as described above had an extremely excellent hair nourishing effect.

[Effect] The present invention uses a hyaluronic acid-protein complex and a placenta extract as active ingredients in a hair tonic base material, thereby achieving cell activation effects of these ingredients.

Effects such as moisturizing properties work synergistically to improve hair,
A hair tonic that enhances and normalizes scalp function and has remarkable hair-nourishing effects such as hair growth, promotion of hair growth, prevention of hair loss, prevention of dandruff and itching, and keeping hair and scalp healthy has been obtained. It is in.

In other words, the present invention provides excellent hair growth and
It has now become possible to provide a hair nourishing agent that has a hair-growth effect.

that's all

Claims (1)

[Claims] A hair nourishing agent characterized by containing a hyaluronic acid-protein complex and a placenta extract as essential ingredients.