JPS61191364A - 抗血栓性材料 - Google Patents
抗血栓性材料Info
- Publication number
- JPS61191364A JPS61191364A JP60031605A JP3160585A JPS61191364A JP S61191364 A JPS61191364 A JP S61191364A JP 60031605 A JP60031605 A JP 60031605A JP 3160585 A JP3160585 A JP 3160585A JP S61191364 A JPS61191364 A JP S61191364A
- Authority
- JP
- Japan
- Prior art keywords
- antithrombotic
- collagen
- mucopolysaccharide
- biocompatibility
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000463 material Substances 0.000 title claims description 58
- 230000002785 anti-thrombosis Effects 0.000 title claims description 33
- 239000003146 anticoagulant agent Substances 0.000 title claims description 20
- 108010035532 Collagen Proteins 0.000 claims description 26
- 102000008186 Collagen Human genes 0.000 claims description 26
- 229920001436 collagen Polymers 0.000 claims description 26
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 18
- -1 aldehyde compound Chemical class 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 15
- 230000000890 antigenic effect Effects 0.000 claims description 11
- 229920000669 heparin Polymers 0.000 claims description 10
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 7
- 229960002897 heparin Drugs 0.000 claims description 7
- 229920002085 Dialdehyde starch Polymers 0.000 claims description 5
- 229920001287 Chondroitin sulfate Polymers 0.000 claims description 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 3
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims description 3
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims description 3
- 229940059329 chondroitin sulfate Drugs 0.000 claims description 3
- 229920002674 hyaluronan Polymers 0.000 claims description 3
- 229960003160 hyaluronic acid Drugs 0.000 claims description 3
- 230000001732 thrombotic effect Effects 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 description 14
- 238000000034 method Methods 0.000 description 13
- 239000002473 artificial blood Substances 0.000 description 12
- 239000007864 aqueous solution Substances 0.000 description 11
- 108010045569 atelocollagen Proteins 0.000 description 10
- 239000000243 solution Substances 0.000 description 8
- 239000012736 aqueous medium Substances 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 208000028659 discharge Diseases 0.000 description 6
- 239000011521 glass Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 208000007536 Thrombosis Diseases 0.000 description 5
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 5
- 241000282472 Canis lupus familiaris Species 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 239000004677 Nylon Substances 0.000 description 4
- 229920002385 Sodium hyaluronate Polymers 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 4
- 229920001778 nylon Polymers 0.000 description 4
- 229940010747 sodium hyaluronate Drugs 0.000 description 4
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 4
- 210000003462 vein Anatomy 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 229920005601 base polymer Polymers 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 description 3
- 238000010030 laminating Methods 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 229920002635 polyurethane Polymers 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004882 Lipase Human genes 0.000 description 2
- 108090001060 Lipase Proteins 0.000 description 2
- 239000004367 Lipase Substances 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 235000019421 lipase Nutrition 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000010287 polarization Effects 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 235000011121 sodium hydroxide Nutrition 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 229920002567 Chondroitin Polymers 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 description 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 description 1
- 235000009685 Crataegus X maligna Nutrition 0.000 description 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 1
- 235000009486 Crataegus bullatus Nutrition 0.000 description 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 description 1
- 235000009682 Crataegus limnophila Nutrition 0.000 description 1
- 235000004423 Crataegus monogyna Nutrition 0.000 description 1
- 240000000171 Crataegus monogyna Species 0.000 description 1
- 235000002313 Crataegus paludosa Nutrition 0.000 description 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 description 1
- 229920000045 Dermatan sulfate Polymers 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 102000016359 Fibronectins Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- 229920002971 Heparan sulfate Polymers 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 125000003172 aldehyde group Chemical group 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000021164 cell adhesion Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- DLGJWSVWTWEWBJ-HGGSSLSASA-N chondroitin Chemical compound CC(O)=N[C@@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1OC1[C@H](O)[C@H](O)C=C(C(O)=O)O1 DLGJWSVWTWEWBJ-HGGSSLSASA-N 0.000 description 1
- 229940094517 chondroitin 4-sulfate Drugs 0.000 description 1
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000005238 degreasing Methods 0.000 description 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 description 1
- 229940051593 dermatan sulfate Drugs 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 150000002337 glycosamines Chemical class 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229960001008 heparin sodium Drugs 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 229920001477 hydrophilic polymer Polymers 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000001155 isoelectric focusing Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000009832 plasma treatment Methods 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001302 tertiary amino group Chemical group 0.000 description 1
- 150000004043 trisaccharides Chemical group 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60031605A JPS61191364A (ja) | 1985-02-21 | 1985-02-21 | 抗血栓性材料 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60031605A JPS61191364A (ja) | 1985-02-21 | 1985-02-21 | 抗血栓性材料 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61191364A true JPS61191364A (ja) | 1986-08-26 |
| JPS6344383B2 JPS6344383B2 (enrdf_load_stackoverflow) | 1988-09-05 |
Family
ID=12335829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60031605A Granted JPS61191364A (ja) | 1985-02-21 | 1985-02-21 | 抗血栓性材料 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61191364A (enrdf_load_stackoverflow) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63277062A (ja) * | 1987-05-08 | 1988-11-15 | Toray Ind Inc | 血管造影カテ−テル |
| JPS63296762A (ja) * | 1987-05-29 | 1988-12-02 | Res Dev Corp Of Japan | 抗血栓性材料の製造法 |
| FR2622104A1 (fr) * | 1987-10-22 | 1989-04-28 | Bioetica Sa | Procede de stabilisation de phases lamellaires lipidiques hydratees, par ex. de liposomes, composition de phases lamellaires lipidiques hydratees, par ex. des liposomes, stabilisees par un emploi d'un support stabilisant a base d'atelocollagene et de glycosaminoglycannes et utilisation en pharmacie ou en cosmetologie |
| JPH01230366A (ja) * | 1988-03-09 | 1989-09-13 | Terumo Corp | 細胞侵入性医用材料 |
| JPH0221875A (ja) * | 1988-07-11 | 1990-01-24 | Terumo Corp | 医療用材料ならびに医療用器具 |
| FR2645455A2 (fr) * | 1987-10-22 | 1990-10-12 | Bioetica Sa | Procede de stabilisation de phases lamellaires lipidiques hydratees, par exemple de liposomes, composition de phases lamellaires lipidiques hydratees, par exemple des liposomes, stabilisees et utilisation en pharmacie ou en cosmetologie sous forme de compositions pharmaceutiques ou cosmetiques |
| JPH09151365A (ja) * | 1995-11-30 | 1997-06-10 | Tombow Pencil Co Ltd | 固形接着剤組成物 |
| JP2008125682A (ja) * | 2006-11-17 | 2008-06-05 | Kanazawa Inst Of Technology | 人体埋め込み部材 |
| JP2011130995A (ja) * | 2009-12-25 | 2011-07-07 | Japan Health Science Foundation | 管腔構造体及び管腔構造体の製造方法 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0536777U (ja) * | 1991-10-18 | 1993-05-18 | 菊水電子工業株式会社 | コネクタの抜け止め防止装置 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58170720A (ja) * | 1981-12-15 | 1983-10-07 | コ−デイス・エウロパ・エヌ・ヴエ | 抗凝固剤とタンパク質との複合体 |
-
1985
- 1985-02-21 JP JP60031605A patent/JPS61191364A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58170720A (ja) * | 1981-12-15 | 1983-10-07 | コ−デイス・エウロパ・エヌ・ヴエ | 抗凝固剤とタンパク質との複合体 |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63277062A (ja) * | 1987-05-08 | 1988-11-15 | Toray Ind Inc | 血管造影カテ−テル |
| JPS63296762A (ja) * | 1987-05-29 | 1988-12-02 | Res Dev Corp Of Japan | 抗血栓性材料の製造法 |
| FR2622104A1 (fr) * | 1987-10-22 | 1989-04-28 | Bioetica Sa | Procede de stabilisation de phases lamellaires lipidiques hydratees, par ex. de liposomes, composition de phases lamellaires lipidiques hydratees, par ex. des liposomes, stabilisees par un emploi d'un support stabilisant a base d'atelocollagene et de glycosaminoglycannes et utilisation en pharmacie ou en cosmetologie |
| FR2645455A2 (fr) * | 1987-10-22 | 1990-10-12 | Bioetica Sa | Procede de stabilisation de phases lamellaires lipidiques hydratees, par exemple de liposomes, composition de phases lamellaires lipidiques hydratees, par exemple des liposomes, stabilisees et utilisation en pharmacie ou en cosmetologie sous forme de compositions pharmaceutiques ou cosmetiques |
| JPH01230366A (ja) * | 1988-03-09 | 1989-09-13 | Terumo Corp | 細胞侵入性医用材料 |
| JPH0221875A (ja) * | 1988-07-11 | 1990-01-24 | Terumo Corp | 医療用材料ならびに医療用器具 |
| JPH09151365A (ja) * | 1995-11-30 | 1997-06-10 | Tombow Pencil Co Ltd | 固形接着剤組成物 |
| JP2008125682A (ja) * | 2006-11-17 | 2008-06-05 | Kanazawa Inst Of Technology | 人体埋め込み部材 |
| JP2011130995A (ja) * | 2009-12-25 | 2011-07-07 | Japan Health Science Foundation | 管腔構造体及び管腔構造体の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6344383B2 (enrdf_load_stackoverflow) | 1988-09-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0241838B1 (en) | Antithrombogenic material | |
| JP3221690B2 (ja) | コラーゲン構造体 | |
| Cassady et al. | Enhancing expanded poly (tetrafluoroethylene)(ePTFE) for biomaterials applications | |
| US5308641A (en) | Biocompatibility of solid surfaces | |
| US4822361A (en) | Tubular prosthesis having a composite structure | |
| DE69418220T2 (de) | Befestigung von Biomolekülen | |
| US4787900A (en) | Process for forming multilayer bioreplaceable blood vessel prosthesis | |
| US5578073A (en) | Thromboresistant surface treatment for biomaterials | |
| US5098977A (en) | Methods and compositions for providing articles having improved biocompatability characteristics | |
| DE3639561C2 (enrdf_load_stackoverflow) | ||
| Bruck | Interactions of synthetic and natural surfaces with blood in the physiological environment | |
| JPS61191364A (ja) | 抗血栓性材料 | |
| WO1992009312A1 (fr) | Materiau pour implants | |
| EP0781089B1 (en) | Thromboresistant surface treatment for biomaterials | |
| WO1996008149A9 (en) | Thromboresistant surface treatment for biomaterials | |
| Iwasaki | Photoassisted surface modification with zwitterionic phosphorylcholine polymers for the fabrication of ideal biointerfaces | |
| US5017670A (en) | Methods and compositions for providing articles having improved biocompatibility characteristics | |
| CA1299937C (en) | Antithrombogenic material | |
| JPS60190966A (ja) | 抗血栓性材料 | |
| CN114432505B (zh) | 一种具有复合水润涂层的聚氨酯材料及其在介入治疗领域的应用 | |
| JPS59183762A (ja) | 新規な抗血栓性材料 | |
| EP0282091A2 (en) | Medical device with heparin slow-release | |
| JPS62152468A (ja) | 複合構造管状臓器補綴物 | |
| Bauser et al. | Improvement of the biocompatibility of polymers through surface modification | |
| JP2014200292A (ja) | 医療デバイスおよびその製造方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |