JPS6117A - ムコ多糖系癌転移抑制剤 - Google Patents
ムコ多糖系癌転移抑制剤Info
- Publication number
- JPS6117A JPS6117A JP11828384A JP11828384A JPS6117A JP S6117 A JPS6117 A JP S6117A JP 11828384 A JP11828384 A JP 11828384A JP 11828384 A JP11828384 A JP 11828384A JP S6117 A JPS6117 A JP S6117A
- Authority
- JP
- Japan
- Prior art keywords
- crosslinked
- cells
- molecular weight
- salt
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 230000002194 synthesizing effect Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11828384A JPS6117A (ja) | 1984-06-11 | 1984-06-11 | ムコ多糖系癌転移抑制剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11828384A JPS6117A (ja) | 1984-06-11 | 1984-06-11 | ムコ多糖系癌転移抑制剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6117A true JPS6117A (ja) | 1986-01-06 |
| JPH0456805B2 JPH0456805B2 (cs) | 1992-09-09 |
Family
ID=14732832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11828384A Granted JPS6117A (ja) | 1984-06-11 | 1984-06-11 | ムコ多糖系癌転移抑制剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6117A (cs) |
Cited By (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988001280A1 (en) * | 1986-08-21 | 1988-02-25 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness or metastatic profusion |
| JPS63502670A (ja) * | 1986-03-14 | 1988-10-06 | バイオ−テクノロジ−・ジエネラル・コ−ポレイシヨン | 抗菌物質として有効なヒアルロン酸の重金属塩 |
| WO1991013624A1 (en) * | 1990-03-05 | 1991-09-19 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Endogenous, suramin-induced, sulfated glycosaminoglycans as anti-cancer agents in humans |
| WO1992001720A1 (fr) * | 1990-07-24 | 1992-02-06 | Seikagaku Kogyo Kabushiki Kaisha | Glycosaminoglycane se combinant a un phospholipide ou a un lipide, production de ce compose et inhibiteur de metastase du cancer |
| US5262403A (en) * | 1986-03-10 | 1993-11-16 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II |
| WO1994020115A3 (en) * | 1993-03-10 | 1994-11-10 | Miles Inc | Hyaluronic acid used as a cancer treatment |
| LT3545B (en) | 1989-09-21 | 1995-11-27 | Norpharmco Inc | Compositions of medicinal preparation and hyaluronic acid for treatment of conditions and disease |
| US5614506A (en) * | 1991-07-03 | 1997-03-25 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US5639738A (en) * | 1992-02-20 | 1997-06-17 | Hyal Pharmaceutical Corporation | Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs |
| US5674857A (en) * | 1992-02-20 | 1997-10-07 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid to repair ischemia reperfusion damage |
| US5676964A (en) * | 1988-05-13 | 1997-10-14 | Fidia, S.P.A. | Crosslinked carboxy polysaccharides |
| WO1997040841A1 (en) * | 1996-04-29 | 1997-11-06 | Hyal Pharmaceutical Corporation | Use of formes f hyaluronic acid (ha) for the treatment of cancer |
| US5733892A (en) * | 1990-07-24 | 1998-03-31 | Seikagaku Corporation | Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same |
| WO1998016559A1 (fr) * | 1996-10-15 | 1998-04-23 | Toray Industries, Inc. | Agent de maturation des canaux cervicaux |
| US5817644A (en) * | 1991-07-03 | 1998-10-06 | Hyal Pharmaceutical Corporation | Targeting of dosages of medicine and therapeutic agents |
| WO1999006114A3 (en) * | 1997-07-31 | 1999-04-08 | Geistlich Soehne Ag | Use of taurolidine or taurultam for the manufacture of a medicament for the prevention of metastases |
| US5942498A (en) * | 1992-02-20 | 1999-08-24 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
| US5990095A (en) * | 1991-07-03 | 1999-11-23 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US6103704A (en) * | 1991-07-03 | 2000-08-15 | Hyal Pharmaceutical Corporation | Therapeutic methods using hyaluronic acid |
| US6641571B2 (en) | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
| EP1393749A1 (en) * | 2002-08-30 | 2004-03-03 | Petrigni, Giuseppe | A pharmaceutical preparation in colloidal form useful in the treatment of skin diseases, comprising hyluronic acid |
| US6806259B2 (en) * | 2001-12-21 | 2004-10-19 | Soft Gel Technologies, Inc. | Hyaluronic Acid in soft gel form |
| US6852255B2 (en) * | 2001-05-02 | 2005-02-08 | Industrial Technology Research Institute | Method for producing water-insoluble polysaccharides |
| JP2005524619A (ja) * | 2002-01-11 | 2005-08-18 | フィディーア・ファルマチェウティチ・ソシエタ・ペル・アチオニ | 腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル |
| EP1301209A4 (en) * | 2000-07-14 | 2005-11-09 | Meditech Res Ltd | HYALURONAN AS A CYTOTOXIC AGENT, PRE-SENSITIZER TO DRUGS AND CHEMIO-SENSITIZER FOR THE TREATMENT OF DISEASES |
| US7151099B2 (en) | 1998-07-31 | 2006-12-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases |
| US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US7910580B2 (en) | 1999-06-04 | 2011-03-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-Fluorouracil in treatment of tumor metastases and cancer |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US8623354B2 (en) | 2005-09-07 | 2014-01-07 | Alchemia Oncology Pty Limited | Therapeutic compositions comprising hyaluronan and therapeutic antibodies as well as methods of treatment |
| US8741970B2 (en) | 1999-01-13 | 2014-06-03 | Alchemia Oncology Pty Limited | Composition and method for the enhancement of the efficacy of drugs |
| US8758819B2 (en) | 2006-09-13 | 2014-06-24 | Enhance Skin Products, Inc. | Cosmetic compositions for the treatment of skin and methods thereof |
| US8937052B2 (en) | 2005-07-27 | 2015-01-20 | Alchemia Oncology Pty Limited | Therapeutic protocols using hyaluronan |
| US9066919B2 (en) | 2000-07-14 | 2015-06-30 | Alchemia Oncology Pty Limited | Hyaluronan as a chemo-sensitizer in the treatment of cancer |
-
1984
- 1984-06-11 JP JP11828384A patent/JPS6117A/ja active Granted
Cited By (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262403A (en) * | 1986-03-10 | 1993-11-16 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II |
| JPS63502670A (ja) * | 1986-03-14 | 1988-10-06 | バイオ−テクノロジ−・ジエネラル・コ−ポレイシヨン | 抗菌物質として有効なヒアルロン酸の重金属塩 |
| WO1988001280A1 (en) * | 1986-08-21 | 1988-02-25 | Board Of Regents, The University Of Texas System | Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness or metastatic profusion |
| US5676964A (en) * | 1988-05-13 | 1997-10-14 | Fidia, S.P.A. | Crosslinked carboxy polysaccharides |
| US6048844A (en) * | 1989-09-21 | 2000-04-11 | Hyal Pharmaceutical Corporation | Treatment of conditions and disease |
| US5985851A (en) * | 1989-09-21 | 1999-11-16 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid or its derivatives in peritoneal dialysis and formulations thereof |
| US5929048A (en) * | 1989-09-21 | 1999-07-27 | Hyal Pharmaceutical Corporation | Treatment of conditions and disease |
| LT3545B (en) | 1989-09-21 | 1995-11-27 | Norpharmco Inc | Compositions of medicinal preparation and hyaluronic acid for treatment of conditions and disease |
| US5852002A (en) * | 1989-09-21 | 1998-12-22 | Hyal Pharmaceutical Corporation | Treatment of conditions and disease |
| US6069135A (en) * | 1989-09-21 | 2000-05-30 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid or its derivatives to enhance delivery of therapeutic agents |
| US5914314A (en) * | 1989-09-21 | 1999-06-22 | Hyal Pharmaceutical Corporation | Use of a form of hyaluronic acid and a medicinal agent for reducing rejection of organs transplantation in mammals |
| US5830882A (en) * | 1989-09-21 | 1998-11-03 | Hyal Pharmaceutical Corporation | Compositions containing a form of hyaluronic acid and a medicinal agent for treating acne in mammals and methods for administration of such composition |
| US5827834A (en) * | 1989-09-21 | 1998-10-27 | Hyal Pharmaceutical Corporation | Method of using hyaluronic acid or its pharmaceutically acceptable salts for the treatment of disease |
| US6194392B1 (en) | 1989-09-21 | 2001-02-27 | Hyal Pharmaceutical Corporation | Treatment of conditions and disease |
| US5932560A (en) * | 1989-09-21 | 1999-08-03 | Hyal Pharmaceutical Corporation | Treatment of conditions and disease |
| US5985850A (en) * | 1989-09-21 | 1999-11-16 | Hyal Pharmaceuticals Corporation | Compositions comprising hyaluronic acid and drugs |
| US5811410A (en) * | 1989-09-21 | 1998-09-22 | Hyal Pharmaceutical Corporation | Method of administering of a hyaluronic acid and an NSAID to decrease side effects of the NSAID |
| WO1991013624A1 (en) * | 1990-03-05 | 1991-09-19 | The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce | Endogenous, suramin-induced, sulfated glycosaminoglycans as anti-cancer agents in humans |
| US5733892A (en) * | 1990-07-24 | 1998-03-31 | Seikagaku Corporation | Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same |
| WO1992001720A1 (fr) * | 1990-07-24 | 1992-02-06 | Seikagaku Kogyo Kabushiki Kaisha | Glycosaminoglycane se combinant a un phospholipide ou a un lipide, production de ce compose et inhibiteur de metastase du cancer |
| EP0493622B1 (en) * | 1990-07-24 | 1997-02-05 | Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) | Phospholipid- or lipid-combining glycosaminoglycan, production thereof, and cancer metastasis inhibitor |
| US5464942A (en) * | 1990-07-24 | 1995-11-07 | Seikagaku Kogyo Kabushiki Kaisha | Phospholipid- or lipid-linked glycosaminoglycan and process for producing the same |
| US5990095A (en) * | 1991-07-03 | 1999-11-23 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US6103704A (en) * | 1991-07-03 | 2000-08-15 | Hyal Pharmaceutical Corporation | Therapeutic methods using hyaluronic acid |
| US5817644A (en) * | 1991-07-03 | 1998-10-06 | Hyal Pharmaceutical Corporation | Targeting of dosages of medicine and therapeutic agents |
| US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US5614506A (en) * | 1991-07-03 | 1997-03-25 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
| US5914322A (en) * | 1992-02-20 | 1999-06-22 | Hyal Pharmaceutical Corporation | Treatment of disease and conditions |
| US5942498A (en) * | 1992-02-20 | 1999-08-24 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
| US6147059A (en) * | 1992-02-20 | 2000-11-14 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
| US5674857A (en) * | 1992-02-20 | 1997-10-07 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid to repair ischemia reperfusion damage |
| US5639738A (en) * | 1992-02-20 | 1997-06-17 | Hyal Pharmaceutical Corporation | Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs |
| WO1994020115A3 (en) * | 1993-03-10 | 1994-11-10 | Miles Inc | Hyaluronic acid used as a cancer treatment |
| WO1997040841A1 (en) * | 1996-04-29 | 1997-11-06 | Hyal Pharmaceutical Corporation | Use of formes f hyaluronic acid (ha) for the treatment of cancer |
| WO1998016559A1 (fr) * | 1996-10-15 | 1998-04-23 | Toray Industries, Inc. | Agent de maturation des canaux cervicaux |
| US8304390B2 (en) | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| WO1999006114A3 (en) * | 1997-07-31 | 1999-04-08 | Geistlich Soehne Ag | Use of taurolidine or taurultam for the manufacture of a medicament for the prevention of metastases |
| US7151099B2 (en) | 1998-07-31 | 2006-12-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Use of taurolidine and/or taurultam for treatment of abdominal cancer and/or for the prevention of metastases |
| US8741970B2 (en) | 1999-01-13 | 2014-06-03 | Alchemia Oncology Pty Limited | Composition and method for the enhancement of the efficacy of drugs |
| US7892530B2 (en) | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US9012444B2 (en) | 1999-06-04 | 2015-04-21 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US8030301B2 (en) | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US7910580B2 (en) | 1999-06-04 | 2011-03-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-Fluorouracil in treatment of tumor metastases and cancer |
| US6641571B2 (en) | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
| EP1301209A4 (en) * | 2000-07-14 | 2005-11-09 | Meditech Res Ltd | HYALURONAN AS A CYTOTOXIC AGENT, PRE-SENSITIZER TO DRUGS AND CHEMIO-SENSITIZER FOR THE TREATMENT OF DISEASES |
| US9066919B2 (en) | 2000-07-14 | 2015-06-30 | Alchemia Oncology Pty Limited | Hyaluronan as a chemo-sensitizer in the treatment of cancer |
| JP2012162569A (ja) * | 2000-07-14 | 2012-08-30 | Alchemia Oncology Pty Ltd | 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン |
| US8287894B2 (en) | 2000-07-14 | 2012-10-16 | Alchemia Oncology Pty Limited | Hyaluronan as a drug pre-sensitizer and chemo-sensitizer in the treatment of disease |
| US8388993B2 (en) | 2000-07-14 | 2013-03-05 | Alchemia Oncology Pty Limited | Hyaluronan-chemotherapeutic agent formulations for the treatment of colon cancer |
| US6852255B2 (en) * | 2001-05-02 | 2005-02-08 | Industrial Technology Research Institute | Method for producing water-insoluble polysaccharides |
| US6806259B2 (en) * | 2001-12-21 | 2004-10-19 | Soft Gel Technologies, Inc. | Hyaluronic Acid in soft gel form |
| US7338943B2 (en) | 2001-12-21 | 2008-03-04 | Soft Gel Technologies, Inc. | Hyaluronic acid in soft gel form |
| US7008932B2 (en) * | 2001-12-21 | 2006-03-07 | Soft Gel Technologies, Inc. | Hyaluronic acid in soft gel form |
| US8551975B1 (en) | 2001-12-21 | 2013-10-08 | Soft Gel Technologies, Inc. | Hyaluronic acid in soft gel form |
| JP2005524619A (ja) * | 2002-01-11 | 2005-08-18 | フィディーア・ファルマチェウティチ・ソシエタ・ペル・アチオニ | 腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル |
| US7838510B2 (en) * | 2002-01-11 | 2010-11-23 | Fidia Farmaceutici S.P.A. | Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumors |
| EP1393749A1 (en) * | 2002-08-30 | 2004-03-03 | Petrigni, Giuseppe | A pharmaceutical preparation in colloidal form useful in the treatment of skin diseases, comprising hyluronic acid |
| US8937052B2 (en) | 2005-07-27 | 2015-01-20 | Alchemia Oncology Pty Limited | Therapeutic protocols using hyaluronan |
| US8623354B2 (en) | 2005-09-07 | 2014-01-07 | Alchemia Oncology Pty Limited | Therapeutic compositions comprising hyaluronan and therapeutic antibodies as well as methods of treatment |
| US8758819B2 (en) | 2006-09-13 | 2014-06-24 | Enhance Skin Products, Inc. | Cosmetic compositions for the treatment of skin and methods thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0456805B2 (cs) | 1992-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |