JPS61145160A - 光学活性なプロピオン酸誘導体の製造法 - Google Patents
光学活性なプロピオン酸誘導体の製造法Info
- Publication number
- JPS61145160A JPS61145160A JP59267436A JP26743684A JPS61145160A JP S61145160 A JPS61145160 A JP S61145160A JP 59267436 A JP59267436 A JP 59267436A JP 26743684 A JP26743684 A JP 26743684A JP S61145160 A JPS61145160 A JP S61145160A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- methoxyphenyl
- propionic acid
- epoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59267436A JPS61145160A (ja) | 1984-12-20 | 1984-12-20 | 光学活性なプロピオン酸誘導体の製造法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59267436A JPS61145160A (ja) | 1984-12-20 | 1984-12-20 | 光学活性なプロピオン酸誘導体の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61145160A true JPS61145160A (ja) | 1986-07-02 |
JPH0461867B2 JPH0461867B2 (US07714131-20100511-C00001.png) | 1992-10-02 |
Family
ID=17444814
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59267436A Granted JPS61145160A (ja) | 1984-12-20 | 1984-12-20 | 光学活性なプロピオン酸誘導体の製造法 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS61145160A (US07714131-20100511-C00001.png) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0338893A2 (fr) * | 1988-04-19 | 1989-10-25 | Synthelabo | Procédé de préparation de (+)-(2S,3S) (Amino-2 phényl) thio-3 hydroxy-2 (methoxy-4 phényl)-3 propionates de méthyle |
EP0342904A2 (en) * | 1988-05-18 | 1989-11-23 | MARION LABORATORIES, INC. (a Delaware corporation) | 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem |
EP0342902A2 (en) * | 1988-05-18 | 1989-11-23 | MARION LABORATORIES, INC. (a Delaware corporation) | 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines |
EP0343474A2 (en) * | 1988-05-24 | 1989-11-29 | F. Hoffmann-La Roche Ag | Process for the preparation of optically pure aminophenylthio- and aminoaphthalenylthio-propanoic acids |
US5008411A (en) * | 1988-05-24 | 1991-04-16 | Hoffmann-La Roche Inc. | Glycidic acid ester and process of preparation |
US5013835A (en) * | 1989-01-11 | 1991-05-07 | Synthelabo | Method of preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)2,3-dihydro-5H-1,5-benzothiazepine-4-one |
AU616517B2 (en) * | 1988-05-18 | 1991-10-31 | Aventis Pharmaceuticals Inc. | Improved resolution of 3-(4-methoxyphenyl)glycidic acid with in situ conversion to alkyl esters |
US5081277A (en) * | 1988-10-03 | 1992-01-14 | Synthelabo | Process for the preparation of propionic acid derivatives |
US5296618A (en) * | 1992-05-14 | 1994-03-22 | Orion-Yhtyma Oy Fermion | Method for the manufacture of the derivatives of propionic acid |
USRE34935E (en) * | 1989-01-11 | 1995-05-09 | Synthelabo | Method for preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-one and chlorinated derivatives thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57136581A (en) * | 1981-02-18 | 1982-08-23 | Nippon Kayaku Co Ltd | Preparation of 1,5-benzothiazepin derivative |
-
1984
- 1984-12-20 JP JP59267436A patent/JPS61145160A/ja active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57136581A (en) * | 1981-02-18 | 1982-08-23 | Nippon Kayaku Co Ltd | Preparation of 1,5-benzothiazepin derivative |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5008434A (en) * | 1988-04-19 | 1991-04-16 | Synthelabo | Process for the preparation of methyl (+)-(2S,3S)-3-[(2-aminophenyl)thio]-2-hydroxy-3-(4-methoxyphenyl)-propionates |
EP0338893A2 (fr) * | 1988-04-19 | 1989-10-25 | Synthelabo | Procédé de préparation de (+)-(2S,3S) (Amino-2 phényl) thio-3 hydroxy-2 (methoxy-4 phényl)-3 propionates de méthyle |
AU616517B2 (en) * | 1988-05-18 | 1991-10-31 | Aventis Pharmaceuticals Inc. | Improved resolution of 3-(4-methoxyphenyl)glycidic acid with in situ conversion to alkyl esters |
EP0342902A3 (en) * | 1988-05-18 | 1991-01-30 | MARION LABORATORIES, INC. (a Delaware corporation) | 2-hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines |
EP0342902A2 (en) * | 1988-05-18 | 1989-11-23 | MARION LABORATORIES, INC. (a Delaware corporation) | 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines |
EP0342904A2 (en) * | 1988-05-18 | 1989-11-23 | MARION LABORATORIES, INC. (a Delaware corporation) | 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem |
EP0343474A2 (en) * | 1988-05-24 | 1989-11-29 | F. Hoffmann-La Roche Ag | Process for the preparation of optically pure aminophenylthio- and aminoaphthalenylthio-propanoic acids |
EP0343474A3 (en) * | 1988-05-24 | 1991-01-23 | F. Hoffmann-La Roche Ag | Process for the preparation of optically pure aminophenylthio- and aminoaphthalenylthio-propanoic acids |
US5008411A (en) * | 1988-05-24 | 1991-04-16 | Hoffmann-La Roche Inc. | Glycidic acid ester and process of preparation |
US5081277A (en) * | 1988-10-03 | 1992-01-14 | Synthelabo | Process for the preparation of propionic acid derivatives |
US5013835A (en) * | 1989-01-11 | 1991-05-07 | Synthelabo | Method of preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)2,3-dihydro-5H-1,5-benzothiazepine-4-one |
US5102998A (en) * | 1989-01-11 | 1992-04-07 | Synthelabo | Method for preparing (+)-(2s,3s)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5h-1,5-benzothiazepine-4-one and chlorinated derivatives thereof |
USRE34935E (en) * | 1989-01-11 | 1995-05-09 | Synthelabo | Method for preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-one and chlorinated derivatives thereof |
US5296618A (en) * | 1992-05-14 | 1994-03-22 | Orion-Yhtyma Oy Fermion | Method for the manufacture of the derivatives of propionic acid |
Also Published As
Publication number | Publication date |
---|---|
JPH0461867B2 (US07714131-20100511-C00001.png) | 1992-10-02 |
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