JPS6113469B2 - - Google Patents
Info
- Publication number
- JPS6113469B2 JPS6113469B2 JP52018626A JP1862677A JPS6113469B2 JP S6113469 B2 JPS6113469 B2 JP S6113469B2 JP 52018626 A JP52018626 A JP 52018626A JP 1862677 A JP1862677 A JP 1862677A JP S6113469 B2 JPS6113469 B2 JP S6113469B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- choh
- symbol
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052739 hydrogen Inorganic materials 0.000 claims 14
- 239000001257 hydrogen Substances 0.000 claims 14
- -1 alkali metal cation Chemical class 0.000 claims 10
- 150000002431 hydrogen Chemical class 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 8
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 claims 3
- 229910052783 alkali metal Inorganic materials 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000004187 tetrahydropyran-2-yl group Chemical group [H]C1([H])OC([H])(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000001207 fluorophenyl group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7043/76A GB1553293A (en) | 1976-02-23 | 1976-02-23 | Azaprostaglandins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS52102253A JPS52102253A (en) | 1977-08-27 |
| JPS6113469B2 true JPS6113469B2 (en, 2012) | 1986-04-14 |
Family
ID=9825554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1862677A Granted JPS52102253A (en) | 1976-02-23 | 1977-02-22 | 133azaprostaglandin |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4182903A (en, 2012) |
| JP (1) | JPS52102253A (en, 2012) |
| CA (1) | CA1100955A (en, 2012) |
| DE (1) | DE2705797A1 (en, 2012) |
| FR (1) | FR2366276A1 (en, 2012) |
| GB (1) | GB1553293A (en, 2012) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62237679A (ja) * | 1986-04-02 | 1987-10-17 | ハ−ゲン バツテリ− ア−ゲ− | 蓄電池板セツトを有する蓄電池の製造方法およびこの方法により製造された蓄電池 |
| JPS63207058A (ja) * | 1987-02-24 | 1988-08-26 | Shin Kobe Electric Mach Co Ltd | 密閉形蓄電池の製造法 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA793452B (en) * | 1978-07-11 | 1980-06-25 | Glaxo Group Ltd | Prostanoid compounds |
| ZA81114B (en) | 1980-01-09 | 1982-01-27 | Glaxo Group Ltd | Prostanoid compounds and their preparation and pharmaceutical formalation |
| US4438111A (en) | 1980-01-09 | 1984-03-20 | Glaxo Group Limited | Prostanoid compounds and pharmaceutical formulations |
| IL62734A (en) * | 1980-04-30 | 1985-10-31 | Glaxo Group Ltd | Aminocyclopentane alkenoic acids and esters,their preparation and pharmaceutical formulations |
| US4371530A (en) * | 1980-07-04 | 1983-02-01 | Glaxo Group Limited | Aminocyclopentanone amides and pharmaceutical formulation |
| DE3162659D1 (en) * | 1980-07-22 | 1984-04-19 | Ono Pharmaceutical Co | 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof |
| CA1191134A (en) * | 1981-04-29 | 1985-07-30 | Eric W. Collington | Aminocyclopentanol acids and esters and their preparation and pharmaceutical formulation |
| IL67041A (en) * | 1981-10-29 | 1988-03-31 | Glaxo Group Ltd | 2-aminocyclopentane alkanoic and alkenoic acid esters,process for their preparation and pharmaceutical compositions containing them |
| US6417228B1 (en) | 1998-11-02 | 2002-07-09 | Alcon Manufacturing, Ltd.. | 13-Aza prostaglandins for the treatment of glaucoma and ocular hypertension |
-
1976
- 1976-02-23 GB GB7043/76A patent/GB1553293A/en not_active Expired
-
1977
- 1977-02-02 US US05/765,039 patent/US4182903A/en not_active Expired - Lifetime
- 1977-02-11 DE DE19772705797 patent/DE2705797A1/de not_active Ceased
- 1977-02-22 FR FR7705105A patent/FR2366276A1/fr active Granted
- 1977-02-22 CA CA272,340A patent/CA1100955A/en not_active Expired
- 1977-02-22 JP JP1862677A patent/JPS52102253A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62237679A (ja) * | 1986-04-02 | 1987-10-17 | ハ−ゲン バツテリ− ア−ゲ− | 蓄電池板セツトを有する蓄電池の製造方法およびこの方法により製造された蓄電池 |
| JPS63207058A (ja) * | 1987-02-24 | 1988-08-26 | Shin Kobe Electric Mach Co Ltd | 密閉形蓄電池の製造法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS52102253A (en) | 1977-08-27 |
| GB1553293A (en) | 1979-09-26 |
| CA1100955A (en) | 1981-05-12 |
| US4182903A (en) | 1980-01-08 |
| FR2366276A1 (fr) | 1978-04-28 |
| FR2366276B1 (en, 2012) | 1981-11-27 |
| DE2705797A1 (de) | 1977-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4256745A (en) | New prostane derivatives and process for their preparation | |
| JPS6113469B2 (en, 2012) | ||
| EP0002234B1 (de) | Neue Prostacyclinderivate, ihre Herstellung und Anwendung | |
| US3845042A (en) | 11-substituted-prostaglandin derivatives | |
| EP0038614A2 (en) | Esters of 5- and 6-oxo-prostaglandins | |
| US4189606A (en) | 13-Azaprostaglandins | |
| HU191057B (en) | Process for the production of new carbacycline-derivatives and of the pharmaceutical preparations containing them | |
| US4035415A (en) | Omega-nor-cycloalkyl-13,14-dehydro-prostaglandins | |
| US4315013A (en) | Certain pyrrole analogs of prostacyclin derivatives | |
| JPS6228788B2 (en, 2012) | ||
| US4496745A (en) | Epoxycarbacyclin derivatives, their preparation and use | |
| JPH08311025A (ja) | ４−ヒドロキシ−２−ピロリドンの製法 | |
| EP0051597B1 (de) | Neue prostacyclinderivate und ihre herstellung | |
| US4983629A (en) | 11-haloprostane derivatives, processes for their preparation and their use as medicinal agents | |
| JPS6228134B2 (en, 2012) | ||
| US4159343A (en) | Prostane derivatives | |
| US3751462A (en) | Process for preparation of substituted fluoromethanesulfonanilides | |
| JPH1087607A (ja) | 含フッ素プロスタグランジン誘導体の製造方法 | |
| JPS6236031B2 (en, 2012) | ||
| JP2991774B2 (ja) | プロパルギルアルコールの新規合成法および該アルコールのプロスタグランジン前駆物質を製造するための使用 | |
| US4156087A (en) | 9-Deoxy-16,16-dimethyl-PGF2 compounds | |
| HU206317B (en) | Process for producing carbacyclines and pharmaceutical compositions containing them | |
| SU707153A1 (ru) | 5-Нитро-7-син-(3-оксоокт-1-транс-енил)бицикло-(2,2,1)-гепт-2-ен как полупродукт полного синтеза простагландинов | |
| JP2000273083A (ja) | プロスタグランジン誘導体 | |
| NO160846B (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive carbacykliner. |