JPS61106570A - 老人精神病薬、１−ピロリジン−２−オンの１−（２−ピリミジニル）−ピペラジニル誘導体 - Google Patents

老人精神病薬、１−ピロリジン−２−オンの１−（２−ピリミジニル）−ピペラジニル誘導体

Info

Publication number
JPS61106570A
JPS61106570A JP60162791A JP16279185A JPS61106570A JP S61106570 A JPS61106570 A JP S61106570A JP 60162791 A JP60162791 A JP 60162791A JP 16279185 A JP16279185 A JP 16279185A JP S61106570 A JPS61106570 A JP S61106570A
Authority
JP
Japan
Prior art keywords
pyrimidinyl
piperazinyl
formulas
formula
pyrrolidinone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60162791A
Other languages
English (en)
Japanese (ja)
Inventor
ジヨセフ　ピー　イエヴイツチ
ロナルド　ジエイ　マツトソン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPS61106570A publication Critical patent/JPS61106570A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP60162791A 1984-07-23 1985-07-23 老人精神病薬、１−ピロリジン−２−オンの１−（２−ピリミジニル）−ピペラジニル誘導体 Pending JPS61106570A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63337184A 1984-07-23 1984-07-23
US633371 1984-07-23

Publications (1)

Publication Number Publication Date
JPS61106570A true JPS61106570A (ja) 1986-05-24

Family

ID=24539376

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60162791A Pending JPS61106570A (ja) 1984-07-23 1985-07-23 老人精神病薬、１−ピロリジン−２−オンの１−（２−ピリミジニル）−ピペラジニル誘導体

Country Status (8)

Country Link
JP (1) JPS61106570A (sv)
CA (1) CA1250291A (sv)
DK (1) DK333485A (sv)
FR (1) FR2567886B1 (sv)
GB (1) GB2162843B (sv)
HU (1) HU194874B (sv)
IT (1) IT1187699B (sv)
SE (1) SE463715B (sv)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001979A1 (en) * 1989-08-02 1991-02-21 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1322199C (en) * 1987-07-15 1993-09-14 Masami Eigyo N-¬(2-oxopyrrolidin-1-yl) acetyl)| piperazine derivatives and drug for senile dementia
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
ES2130116T3 (es) * 1989-04-22 1999-07-01 Wyeth John & Brother Ltd Derivados de piperazina.
CA2304682A1 (en) 1997-10-09 1999-04-22 Fujisawa Pharmaceutical Co., Ltd. New process for producing aminopiperazine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
DE3361609D1 (en) * 1982-03-24 1986-02-06 Prodes Sa New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001979A1 (en) * 1989-08-02 1991-02-21 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives
US5250528A (en) * 1989-08-02 1993-10-05 Fujisawa Pharmaceutical Co., Ltd. New aminopiperazine derivatives

Also Published As

Publication number Publication date
CA1250291A (en) 1989-02-21
FR2567886A1 (fr) 1986-01-24
FR2567886B1 (fr) 1988-03-25
DK333485A (da) 1986-01-24
HUT38342A (en) 1986-05-28
DK333485D0 (da) 1985-07-22
SE463715B (sv) 1991-01-14
GB2162843A (en) 1986-02-12
IT8521657A0 (it) 1985-07-22
GB2162843B (en) 1988-04-20
HU194874B (en) 1988-03-28
IT1187699B (it) 1987-12-23
GB8518452D0 (en) 1985-08-29
SE8503557L (sv) 1986-01-24
SE8503557D0 (sv) 1985-07-22

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