JPS6056923A - Extraction of guava leaf extract - Google Patents

Abstract

PURPOSE:To produce guava leaf extract useful as a health food or a raw material of pharmaceuticals, etc., economically in an industrial scale, by extracting the dried and crushed guava leaf with a mixture of water and a primary alcohol or a lower ketone under specific condition. CONSTITUTION:Dried leaves of guava are crushed and extracted with a mixture of water and a primary alcohol or a lower ketone at 50-80 deg.C, and the filtrate is concentrated under reduced pressure to obtain the objective guava leaf extract. The ratio of water to the primary alcohol or lower ketone is preferably 1:1- 3:7. A high-quality extract having unique flavor can be produced at a low temperature in a short time and high yield by the use of a mixture of water and a primary alcohol or lower ketone as the extraction solvent, and furthermore, the amount of the solvent can be decreased.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an extraction method for efficiently extracting a high-quality extract from guava leaves.

Guava leaves have been decocted and an aqueous solution has been drunk in China since ancient times. In recent years, it has been found to be effective in treating diabetes, high blood pressure, constipation, obesity, and diarrhea, and has been gaining popularity in Japan. Because of these effects, it is thought that it contains ingredients that are useful for maintaining health, and the number of people who drink it not only for the treatment of diseases but also for so-called health purposes is increasing. However, the method of brewing and drinking over a long period of time is troublesome and difficult for most drinkers.

Therefore, it is desirable to extract the kissing ingredient and provide it in a form that is easily drinkable by anyone and suitable for distribution.

However, in the conventional extract obtained from an extract extracted only with water, there is a risk that the components may change during the process of heating at high temperature for a long time and concentrating under reduced pressure. Moreover, industrial production requires large amounts of water and large-scale equipment. Furthermore, since this method does not extract water-insoluble components such as essential oils, only a bitter extract lacking aromatic flavor can be obtained, and it cannot be said to be an appropriate method.

The present inventors investigated various methods for efficiently extracting extracts with good flavor and no bitterness, and found that
We have found that it is appropriate to carry out the extraction treatment under certain conditions using a mixture of lower alcohols or lower ketones.

Namely, in the method of the present invention, dried guava leaves are crushed and heated at 50°C to 8°C in a mixture of water and primary alcohol or lower ketone.
It consists of extraction at 0°C and concentration of the filtrate under reduced pressure. The blending ratio of the liquid mixture used in this method is preferably in the range of 1:1 to 3 nia to sufficiently elute water-soluble components and alcohol-soluble components. Add this mixture 2 to 4 times by weight to the dry guava leaves and heat at 50°C.
When heating and extracting at a temperature of 80℃, the hot alcohol acts on the tissue cells and promotes the elution of the extract, so it is not necessary to maintain the reflux temperature, and extraction can be performed in a short time with a small amount of solvent. be able to. The extract can be extracted more completely by filtering the extract under reduced pressure, adding a mixed solution to the residue, and processing again. The extract was heated to 100-200°C at 40-50°C. , tm Hf under reduced pressure. The solvent is easily distilled out as an azeotropic mixture of water and primary alcohol or lower ketone, leaving a highly pure extract without any change in components during concentration. The liquid extract has an aroma and can be used as is, but it can be vacuum dried or freeze-dried to obtain a powder extract. This powdered extract is easily soluble in water, has an aroma, and can be drunk without the bitter taste of a decoction.

The first feature of the method of the present invention is that by also extracting alcohol-soluble components, it is possible to obtain an extract containing aromas and useful components that are completely absent from conventional decoctions. The second feature is that the presence of alcohol accelerates the elution of the extract components, so it can be processed at low temperatures and in a short time, resulting in a high yield of high-quality extract with no change in components and no bitterness. The third feature is that extraction can be carried out efficiently with a small amount of solvent, making the equipment compact and suitable for industrialization.In this way, the method of the present invention produces a high-quality, fragrant extract in a short time at low temperatures. can be extracted easily, and only requires a small amount of solvent.

Since the extract extracted by the method of the present invention contains the useful components of guava leaves as they are, it has a wide range of uses as a health drink, health food, and pharmaceutical raw material.

Next, the method of the present invention will be explained in more detail with reference to Examples and Reference Examples.

Example 50 f of dried guava leaves are crushed and heated in water-ethyl alcohol for a period of time. Filter under reduced pressure with filter paper and add 100r of mixed liquid to the residue.
The filtrates were combined and concentrated under reduced pressure at 40-50°C and 100-200 tmHt to obtain liquid extract 30-. This was vacuum dried until the moisture level ff was 15% or less to obtain powder extract 109. The yield on dry leaves is 20%.

The analysis results of the above powder extract are shown in Table 1-Column A.

For reference, crush 50 f of dried Aba leaves, add 400 g of water, and make 95 g.
Heat at ~100°C for 1 hour. Processed in the same manner as in the example,
Re-extract with 200 rnt of water. Combine the filtrate and make 70~8
Concentration under reduced pressure at 230-355 mHf at 0°C yielded liquid extract 23d.

This was vacuum dried until the moisture content became 5% or less to obtain powder extract 77. The yield on dry leaves is 14%. This powdered extract is diluted with water.

Unlike the examples, it had a strong bitter taste and no aroma.

The analysis results of the above powder extract are shown in Table 1-column B.

Claims (2)

[Claims] (1) Extract the extract from guava leaves. Hits the. Crush dry guava leaves, add water-primary alcohol or lower ketone mixture and heat to 50'C to 80C,
A method for extracting guava leaf extract, which comprises concentrating the filtrate under reduced pressure. (2) Claim 1, wherein the mixing ratio of water and primary alcohol or lower ketone mixture is 1:1 to 3.
Extraction method of guava leaf extract as described in section.