JPS60241448A - 医療用具の製法 - Google Patents
医療用具の製法Info
- Publication number
- JPS60241448A JPS60241448A JP59098399A JP9839984A JPS60241448A JP S60241448 A JPS60241448 A JP S60241448A JP 59098399 A JP59098399 A JP 59098399A JP 9839984 A JP9839984 A JP 9839984A JP S60241448 A JPS60241448 A JP S60241448A
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- group
- blood
- compound
- polyurethane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 20
- 239000005056 polyisocyanate Substances 0.000 claims description 10
- 229920001228 polyisocyanate Polymers 0.000 claims description 10
- 229920000642 polymer Polymers 0.000 claims description 10
- -1 polysiloxane Polymers 0.000 claims description 9
- 125000001841 imino group Chemical group [H]N=* 0.000 claims description 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 4
- 229910052739 hydrogen Inorganic materials 0.000 claims description 4
- 239000001257 hydrogen Substances 0.000 claims description 4
- 125000003396 thiol group Chemical group [H]S* 0.000 claims description 4
- 239000004952 Polyamide Substances 0.000 claims description 3
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 3
- 229920002647 polyamide Polymers 0.000 claims description 3
- 229920000570 polyether Polymers 0.000 claims description 3
- 125000003277 amino group Chemical group 0.000 claims description 2
- 239000000178 monomer Substances 0.000 claims description 2
- 229920001296 polysiloxane Polymers 0.000 claims description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 16
- 239000008280 blood Substances 0.000 description 13
- 210000004369 blood Anatomy 0.000 description 13
- 238000000034 method Methods 0.000 description 9
- 238000006243 chemical reaction Methods 0.000 description 8
- 239000004814 polyurethane Substances 0.000 description 8
- 229920002635 polyurethane Polymers 0.000 description 8
- 239000002904 solvent Substances 0.000 description 7
- WADSJYLPJPTMLN-UHFFFAOYSA-N 3-(cycloundecen-1-yl)-1,2-diazacycloundec-2-ene Chemical compound C1CCCCCCCCC=C1C1=NNCCCCCCCC1 WADSJYLPJPTMLN-UHFFFAOYSA-N 0.000 description 5
- 239000004698 Polyethylene Substances 0.000 description 5
- 230000002785 anti-thrombosis Effects 0.000 description 5
- 229920000573 polyethylene Polymers 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 229920003226 polyurethane urea Polymers 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 125000002947 alkylene group Chemical group 0.000 description 2
- 239000002473 artificial blood Substances 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 125000005442 diisocyanate group Chemical group 0.000 description 2
- RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 description 2
- 239000012948 isocyanate Substances 0.000 description 2
- IQPQWNKOIGAROB-UHFFFAOYSA-N isocyanate group Chemical group [N-]=C=O IQPQWNKOIGAROB-UHFFFAOYSA-N 0.000 description 2
- 150000002513 isocyanates Chemical class 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000011342 resin composition Substances 0.000 description 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
- 229920002803 thermoplastic polyurethane Polymers 0.000 description 2
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- 239000005057 Hexamethylene diisocyanate Substances 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004433 Thermoplastic polyurethane Substances 0.000 description 1
- 229920001807 Urea-formaldehyde Polymers 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000013877 carbamide Nutrition 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 150000004985 diamines Chemical class 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- ANJPRQPHZGHVQB-UHFFFAOYSA-N hexyl isocyanate Chemical compound CCCCCCN=C=O ANJPRQPHZGHVQB-UHFFFAOYSA-N 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920006122 polyamide resin Polymers 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 description 1
- PWBHRVGYSMBMIO-UHFFFAOYSA-M tributylstannanylium;acetate Chemical compound CCCC[Sn](CCCC)(CCCC)OC(C)=O PWBHRVGYSMBMIO-UHFFFAOYSA-M 0.000 description 1
- 238000007039 two-step reaction Methods 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Polyurethanes Or Polyureas (AREA)
- Paints Or Removers (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59098399A JPS60241448A (ja) | 1984-05-15 | 1984-05-15 | 医療用具の製法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59098399A JPS60241448A (ja) | 1984-05-15 | 1984-05-15 | 医療用具の製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60241448A true JPS60241448A (ja) | 1985-11-30 |
| JPH0155023B2 JPH0155023B2 (enrdf_load_stackoverflow) | 1989-11-22 |
Family
ID=14218755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59098399A Granted JPS60241448A (ja) | 1984-05-15 | 1984-05-15 | 医療用具の製法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60241448A (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63206254A (ja) * | 1987-02-24 | 1988-08-25 | 小柳 仁 | 医療用部材 |
| WO1988007872A1 (en) * | 1987-04-09 | 1988-10-20 | Terumo Kabushiki Kaisha | Medical material and process for its production |
| US5670558A (en) * | 1994-07-07 | 1997-09-23 | Terumo Kabushiki Kaisha | Medical instruments that exhibit surface lubricity when wetted |
| WO2003078503A1 (en) | 2002-03-14 | 2003-09-25 | Croda International Plc | Protein-silane / siloxane copolymers, their preparation and their use |
| WO2005110507A1 (ja) * | 2004-05-14 | 2005-11-24 | Japan Stent Technology Co., Ltd. | ガイドワイヤ |
| US10640614B2 (en) | 2016-07-28 | 2020-05-05 | 3M Innovative Properties Company | Segmented silicone polyamide block copolymers and articles containing the same |
| US10865330B2 (en) | 2016-07-28 | 2020-12-15 | 3M Innovative Properties Company | Segmented silicone polyamide block copolymers and articles containing the same |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6096259A (ja) * | 1983-10-31 | 1985-05-29 | ユニチカ株式会社 | 抗血栓性医療材料の製造法 |
-
1984
- 1984-05-15 JP JP59098399A patent/JPS60241448A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6096259A (ja) * | 1983-10-31 | 1985-05-29 | ユニチカ株式会社 | 抗血栓性医療材料の製造法 |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63206254A (ja) * | 1987-02-24 | 1988-08-25 | 小柳 仁 | 医療用部材 |
| WO1988007872A1 (en) * | 1987-04-09 | 1988-10-20 | Terumo Kabushiki Kaisha | Medical material and process for its production |
| US5670558A (en) * | 1994-07-07 | 1997-09-23 | Terumo Kabushiki Kaisha | Medical instruments that exhibit surface lubricity when wetted |
| WO2003078503A1 (en) | 2002-03-14 | 2003-09-25 | Croda International Plc | Protein-silane / siloxane copolymers, their preparation and their use |
| AU2003216815B2 (en) * | 2002-03-14 | 2007-05-24 | Croda International Plc | Protein-silane / siloxane copolymers, their preparation and their use |
| JP4763239B2 (ja) * | 2002-03-14 | 2011-08-31 | クロダ・インターナショナル・パブリック・リミテッド・カンパニー | タンパク質−シラン／シロキサンコポリマー、それらの調製、及びそれらの使用 |
| US8048846B2 (en) | 2002-03-14 | 2011-11-01 | Croda International Plc | Protein-silane/siloxane copolymers, their preparation and their use |
| WO2005110507A1 (ja) * | 2004-05-14 | 2005-11-24 | Japan Stent Technology Co., Ltd. | ガイドワイヤ |
| US10640614B2 (en) | 2016-07-28 | 2020-05-05 | 3M Innovative Properties Company | Segmented silicone polyamide block copolymers and articles containing the same |
| US10865330B2 (en) | 2016-07-28 | 2020-12-15 | 3M Innovative Properties Company | Segmented silicone polyamide block copolymers and articles containing the same |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0155023B2 (enrdf_load_stackoverflow) | 1989-11-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0068385B1 (en) | Thermoplastic elastomers for medical use as moulded articles brought into direct contact with blood | |
| US5541305A (en) | Composition compatible with blood | |
| US5061777A (en) | Thromboresistant polyetherurethane compounds and process for its production | |
| JP2537580B2 (ja) | 血液適合性が改善されたフッ素化ポリウレタンの製造方法 | |
| EP0404515A2 (en) | Medical devices having a coating of amine rich fluorinated polyurethaneurea and an antithrombogenic agent covalently bonded thereto and method for their preparation | |
| CS199560B2 (en) | Method of preparing thermoplastic polytetramethylene-etherpolyurethan-urea resin | |
| US4944767A (en) | Synthetic material apt to stably adsorb high quantities of heparin, and process for the production thereof | |
| US5116361A (en) | Sulfonated polyethyleneoxide-substituted polymers with improved blood compatibility | |
| JPS5841563A (ja) | 抗凝血性材料 | |
| JPS60241448A (ja) | 医療用具の製法 | |
| JPS60238315A (ja) | 抗血栓性ポリウレタン又はポリウレタンウレア及びその製造方法、ならびに血液接触医療器具 | |
| Yen et al. | Complexes of heparin with elastomeric positive polyelectrolytes | |
| US4465480A (en) | Blood transfusion tubes and devices for use in contact with human blood | |
| US5216087A (en) | Process for the preparation of sulfonated polyethyleneoxide-substituted polymers with improved blood compatibility | |
| JPS58188458A (ja) | 抗血栓性エラストマ−、その製造方法及び抗血栓性エラストマ−よりなる成形体 | |
| JP4097762B2 (ja) | 抗血栓性医用材料 | |
| KR100285238B1 (ko) | 폴리디메틸실록산(pdms)과 폴리에틸렌글리콜(peg)이 결합된 의료용 폴리우레탄 및 그의 제조방법 | |
| JPS6222818A (ja) | 抗血栓性ウレタン樹脂の製造方法 | |
| JP2001136960A (ja) | 細胞培養膜 | |
| JPS6121419B2 (enrdf_load_stackoverflow) | ||
| JPS60236658A (ja) | 抗血栓性ポリウレタン又はポリウレタンウレアの製造方法 | |
| JP3173615B2 (ja) | 血液適合性材料 | |
| JPH032549B2 (enrdf_load_stackoverflow) | ||
| JPS6173666A (ja) | ポリウレタン又はポリウレタンウレアからなる抗血栓性材料及びその製造方法 | |
| JPS58206753A (ja) | 抗血液凝固性医療材料の製造法 |