JPS60156471A - Artificial dialytic apparatus - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention] [Technical field to which the invention pertains] The present invention provides a method for controlling a predetermined ultrafiltration pressure by controlling the flow path resistance of an air suction pipe of a meter installed in a non-dialysate circuit discharge line in a dialyzer. At the same time, when measuring the ultrafiltration capacity, outside air is introduced into the measuring instrument through the air suction pipe and the ultrafiltered liquid is introduced into the measuring instrument after it is surely emptied. Regarding artificial dialysis equipment.

[Prior art]

As is well known, the ultrafiltration capacity (hereinafter referred to as UFRP) of the dialyzer of an artificial dialysis machine differs depending on the individual dialyzer, and when dialysis continues.

It gradually decreases over time. Further, even if the dialyzer is the same, the UFRP will be different for different patients. For this reason.

For artificial dialysis machines that perform predetermined ultrafiltration based on UFRP, UFRP is periodically or as needed.
are being measured.

Conventionally, as this type of artificial dialysis device, for example,
A positive pressure type artificial dialysis device disclosed in Japanese Patent No. 6-84606 is known. Dialyzer 1 of the above device
The dialysate circuit in K, as shown in FIG. and a flow path switching means 8 (
three-way cock) and - blood pressure sensor 9 and dialysate pressure signal sensor 1
a TMP calculation circuit 11 that inputs a signal from 0 and outputs a signal to the dialysate supply pump 5 that makes the difference between the transmembrane pressure (hereinafter referred to as TMP) obtained by predetermined processing and the set value zero; , a timing circuit (not shown) for controlling the operation timing of the channel opening/closing means 5 and the channel switching means 8. The metering line 6 includes a chamber 12 in the form of a drip cylinder whose air chamber is open to the outside air, a metering pump 13 (roller pump), and a liquid line 6 that outputs a signal to the metering pump 15 to keep the liquid level in the chamber 12 at a constant value. It consists of a surface sensor (not shown). The control system including this liquid level sensor is designed to operate only when dialysate supply is interrupted, that is, when UFRP is measured.

In the above configuration, dialysis is performed by opening the channel opening/closing means 6 and placing the channel switching means 8 in a position where the discharge rhino 4 and the discharge destination 7 are communicated with each other. At this time, the TMP is controlled according to the setting by the operation of the TMP calculating circuit 11, so that ultrafiltration corresponding to the setting TMP is continuously performed in the dialyzer 1. On the other hand, the UFRP measurement is performed with the flow path opening/closing means 5 closed and the flow path switching means 8 placed in a position where the discharge line 4 and the measuring line 6 are in communication with each other (the inside of the chamber 12 is in communication with the outside air). ). At this time as well = T
Since the TMP is controlled according to the setting by the operation of the MP calculation circuit 11, the setting TMP is controlled in the dializer 1.
Ultrafiltration corresponding to the above continues. The liquid in the discharge line 4 is guided to the metering line 6, flows into the chamber 12, and is discharged by a total of one pump 15 operated by a control system including a liquid level sensor.

This keeps the liquid level in the chamber 12 constant,
The ultrafiltration amount (hereinafter referred to as UF) is calculated from the discharge amount (discharge amount) of the metering pump 15, and the ultrafiltration rate (hereinafter referred to as -UF, R) is calculated from the operating time of the metering pump 16. . Then, from TMP at this time, UFRP (= U
FR/TMP) is calculated, and a predetermined ultrafiltration is then performed based on this UFRP.

However, conventional artificial dialysis machines are equipped with a dialysate supply pump and a metering pump, and configure a control system with each as an operating end, making the machine complex and expensive ( The problem is that pumps are generally expensive.

[Purpose of the invention]

The present invention has been made in view of these points, and its purpose is to provide an artificial dialysis device that is simple in construction and inexpensive.

[Structure of the invention]

The artificial dialysis apparatus of the present invention that achieves the above object is an artificial dialysis apparatus that supplies dialysate by a pressure pump installed in a dialyzer's dialysate circuit discharge line, which is connected to a discharge line between the dialyzer and the pressure pump. A measuring device that communicates with the outside air via a tube that has a flow path resistance variable means operated by an external signal, a circuit for dialysis in the dialysate circuit, and a circuit for measuring ultrafiltration capacity. and a signal processing unit that inputs a blood pressure signal and a dialysate pressure signal in the dialyzer, performs predetermined processing, and outputs a signal for operating the flow path resistance variable means. By operating the path resistance variable means, the amount of air sucked into the discharge line is adjusted, thereby adjusting the dialysate pressure and controlling the ultrafiltration pressure. After drawing outside air into the meter and ensuring that it is emptied, the ultrafiltered liquid is introduced into the meter.

[Embodiments of the invention]

Hereinafter, the present invention will be explained with reference to the drawings.

FIG. 2 is a main part configuration diagram showing an embodiment of the present invention.
The same symbols as those shown in FIG. 1 are used interchangeably. This embodiment consists of a dialyzer 1 and its peripheral devices, and a microcontroller that inputs signals from the peripheral devices and signals from an operation panel 21 for setting UPI (etc.), performs predetermined processing, and operates the peripheral devices. It is composed of a signal processing section 22 consisting of a computer.The signal processing section 22 is
The TMP setting value is calculated based on the setting value (desired UFR) from the operation panel 21 and the UFRP billing method will be described later), and the output signals of the blood pressure sensor 9 and dialysate pressure sensor 10 are calculated. A control signal is output to the diaphragm mechanism 33 (to be described later) to make the difference between the measured TMP value and the set value zero, periodically or when a command is given from the operation panel 21. At this time, a UFRP measurement circuit is configured (constructed by operating a solenoid valve, which will be described later), and a signal from a meter 31, which will be described later, and a dialysate fluid pressure sensor 10 are
The UFRP is constructed by inputting signals etc. from the UFRP and performing predetermined processing. The dialysate circuit of the dialyzer 1 includes a control valve 23 that automatically adjusts the flow rate of the dialysate to a constant flow rate, a solenoid valve 24 operated by a signal processing section 22, and a dialysis pressure sensor 1.
0 (the output signal is input to the signal processing unit 22), a solenoid valve 25 operated by the signal processing unit 22, and a pressure relief pump 26 (gear pump) that rotates at a constant speed.
a bypass line 28 having a solenoid valve 27 operated by the signal processing section 22, and a container 2.
9 and an ultrasonic sensor 30 (the output signal is input to the signal processing section 22).
2, and an air suction line 34 made of a flexible pipe having a throttle mechanism 63 (means for pressing the pipe 34 to vary the flow path resistance) operated by a signal processing section. On the other hand, the blood circuit of the dialyzer 1 includes a blood pump 55 that rotates at a constant speed, an arterial chamber 36, a venous chamber 57, and a hydraulic pressure sensor 9 (the output signal is sent to a signal processing unit 22).
).

In the above configuration, dialysis is performed by continuously flowing blood from the patient into the blood circuit of the dialyzer 1 and by using the solenoid valve 24.
and 25 are opened, the solenoid valve 27 is closed, and the depressurizing bong 26 is driven to continuously flow the dialysate into the dialysate circuit of the dialyzer 1 at a substantially constant flow rate (flow rate set by the control valve 25). (The flow path is supply line 2 → dialyzer 1 →
(becomes discharge line 4). At this time, the signal processing unit 22
The throttling mechanism 33 is operated to adjust the amount of air suctioned through the air suction pipe 34 to set the TMP during dialysis to a predetermined value (by controlling the TMP with the throttling mechanism, a predetermined UF
R).

On the other hand, UFRP measurement is performed through the following two steps. That is, as a first step, dialyzer 1
While maintaining the blood circuit in the dialysis state, the solenoid valve 24 is closed and the solenoid valves 25 and 27 are opened to form a flow path for flowing dialysate from the supply source to the discharge destination 6 via the bypass line 28 ( (The supply of dialysate to the dialyzer 1 is stopped.) In this configuration, the measuring instrument 51 (container 29) Ic
The remaining liquid is drained and completely emptied (air enters the container 29 via the air suction line 34 to ensure emptying). At this time as well, since the control system with the throttle mechanism 63 as the operating end is operating, ultrafiltration is performed under a predetermined TMP. In this state, enter the second step, close the solenoid valve 25, and configure the flow path from dialyzer 1 → discharge 2-in-4 → metering line 32 → discharge destination 6. be introduced.

In this second step, the signal processing unit 22 uses the liquid level detection signals from the two ultrasonic sensors 30 as a trigger to count the time T during which the ultrafiltrated liquid fills the container 29,
Calculate UFR (=V/TV, where V is the volume of the container 29). Then, from TMP at this time to UFRP (= UFR/T
MP) and stores it in RAM as an updated UFRP.

Note that the present invention does not limit the flow path resistance variable means in the pipe that communicates the measuring instrument with the outside air to the above-mentioned embodiment (throttling mechanism), but may also include other means, such as a globe valve (control valve). It's okay.

〔Effect of the invention〕

As explained above, according to the artificial dialysis apparatus of the present invention, TMP can be achieved without manipulating the flow path resistance of the air suction pipe of the meter installed in the dialysate circuit discharge line of the dialyzer.
2. When measuring UFRP while controlling to obtain a predetermined UFR, outside air is introduced into the measuring instrument through the air suction pipe to completely empty it.

Since the ultrafiltrated liquid is introduced into the system and measured, there is no need for a pump or the like for UF measurement. Therefore, the configuration of the device is simple and inexpensive.

[Brief explanation of drawings]

FIG. 1 is a block diagram showing a conventional example, and FIG. 2 is a block diagram showing an embodiment of the present invention. DESCRIPTION OF SYMBOLS 1... Dialyzer, 2... Supply line of dialysate circuit, 4... Discharge line of dialysate circuit, 6... Drain destination, 9... Blood pressure sensor, 10... Dialysate pressure sensor
21... Operation panel, 22... Signal processing section, 23.
...Control valve, 26...Pressure pump, 61...Measuring device, 33... Throttle mechanism, 34...Air suction line. Chest 1

Claims (1)

[Scope of Claims] In an artificial dialysis apparatus that supplies dialysate by a pressure relief pump installed in a dialyzer's dialysate circuit discharge line, the container communicates with a discharge main between the dialyzer and the pressure relief pump, and comprises an external a meter communicating with the outside air via a pipe having a channel resistance variable means operated by a signal; a means for switching the dialysate circuit between a circuit for dialysis and a circuit for measuring ultrafiltration capacity; and the dialyzer. a signal processing unit that manually processes the blood pressure signal and dialysate pressure signal in a predetermined manner and outputs a signal for operating the flow path resistance variable means; Adjust the amount of suction air. This allows the dialysate pressure to be adjusted to control the ultrafiltration pressure, and when measuring ultrafiltration capacity, after drawing outside air into the meter through the nozzle and ensuring that it is emptied, the ultrafiltration pressure can be adjusted. An artificial dialysis device, characterized in that a filtered liquid is introduced into the meter.