JPS5970692A - 新規の有機珪素化合物、その非毒性塩、その製法及び該化合物を有効成分とする抗腫瘍剤 - Google Patents

新規の有機珪素化合物、その非毒性塩、その製法及び該化合物を有効成分とする抗腫瘍剤

Info

Publication number
JPS5970692A
JPS5970692A JP57181782A JP18178282A JPS5970692A JP S5970692 A JPS5970692 A JP S5970692A JP 57181782 A JP57181782 A JP 57181782A JP 18178282 A JP18178282 A JP 18178282A JP S5970692 A JPS5970692 A JP S5970692A
Authority
JP
Japan
Prior art keywords
group
substituted
alkyl group
thio
ethylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57181782A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0322394B2 (cg-RX-API-DMAC7.html
Inventor
Shigeru Toyoshima
豊島　滋
Masatsune Kurono
昌庸 黒野
Ryoichi Unno
良一 海野
Koichi Ito
光一 伊藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shin-Etsu Chemical Co Ltd
Sanwa Kagaku Kenkyusho Co Ltd
Original Assignee
Shin-Etsu Chemical Co Ltd
Sanwa Kagaku Kenkyusho Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shin-Etsu Chemical Co Ltd, Sanwa Kagaku Kenkyusho Co Ltd filed Critical Shin-Etsu Chemical Co Ltd
Priority to JP57181782A priority Critical patent/JPS5970692A/ja
Priority to EP83306255A priority patent/EP0109195B1/en
Priority to DE8383306255T priority patent/DE3378913D1/de
Priority to US06/542,439 priority patent/US4560679A/en
Publication of JPS5970692A publication Critical patent/JPS5970692A/ja
Publication of JPH0322394B2 publication Critical patent/JPH0322394B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57181782A 1982-10-16 1982-10-16 新規の有機珪素化合物、その非毒性塩、その製法及び該化合物を有効成分とする抗腫瘍剤 Granted JPS5970692A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP57181782A JPS5970692A (ja) 1982-10-16 1982-10-16 新規の有機珪素化合物、その非毒性塩、その製法及び該化合物を有効成分とする抗腫瘍剤
EP83306255A EP0109195B1 (en) 1982-10-16 1983-10-14 Antitumor organosilicon compounds and their preparation
DE8383306255T DE3378913D1 (en) 1982-10-16 1983-10-14 Antitumor organosilicon compounds and their preparation
US06/542,439 US4560679A (en) 1982-10-16 1983-10-17 Organosilicon compounds and antitumor agents containing the compound as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57181782A JPS5970692A (ja) 1982-10-16 1982-10-16 新規の有機珪素化合物、その非毒性塩、その製法及び該化合物を有効成分とする抗腫瘍剤

Publications (2)

Publication Number Publication Date
JPS5970692A true JPS5970692A (ja) 1984-04-21
JPH0322394B2 JPH0322394B2 (cg-RX-API-DMAC7.html) 1991-03-26

Family

ID=16106783

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57181782A Granted JPS5970692A (ja) 1982-10-16 1982-10-16 新規の有機珪素化合物、その非毒性塩、その製法及び該化合物を有効成分とする抗腫瘍剤

Country Status (4)

Country Link
US (1) US4560679A (cg-RX-API-DMAC7.html)
EP (1) EP0109195B1 (cg-RX-API-DMAC7.html)
JP (1) JPS5970692A (cg-RX-API-DMAC7.html)
DE (1) DE3378913D1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61155390A (ja) * 1984-12-28 1986-07-15 Sanwa Kagaku Kenkyusho:Kk 新規な有機珪素化合物、その非毒性塩、これらの製法並びにそれを有効成分とする抗腫瘍剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4625031A (en) * 1982-01-18 1986-11-25 Dow Corning Corporation Silane compounds
US4712865A (en) * 1987-01-05 1987-12-15 Baxter Travenol Laboratories Dye containing silicon polymer composition
US4714770A (en) * 1987-01-05 1987-12-22 Baxter Travenol Laboratories, Inc. Dye silane compositions
JPS63170387A (ja) * 1987-01-05 1988-07-14 Sanwa Kagaku Kenkyusho Co Ltd 有機珪素化合物、その製法及び該化合物を有効成分とする抗腫瘍剤
US6433206B1 (en) * 2001-11-05 2002-08-13 Crompton Corporation Process for preparing silylorganomercaptans

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5738789A (en) * 1980-08-14 1982-03-03 Shin Etsu Chem Co Ltd 2-(2-(aminoethylthio)) ethyltrimethylsilane and antitumor agent comprising it as active ingredient
JPS5823626A (ja) * 1981-08-04 1983-02-12 Shin Etsu Chem Co Ltd 抗腫瘍剤
JPS58124719A (ja) * 1982-01-20 1983-07-25 Shin Etsu Chem Co Ltd 抗腫瘍剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL24062A (en) * 1965-07-29 1971-06-23 Broza M Silicon containing beta-phenylethylamines
US4360686A (en) * 1981-09-03 1982-11-23 The Dow Chemical Company Silylation of organic compounds
US4434161A (en) * 1982-09-29 1984-02-28 Sandoz, Inc. Sulfur and silicon-containing fatty acid amides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5738789A (en) * 1980-08-14 1982-03-03 Shin Etsu Chem Co Ltd 2-(2-(aminoethylthio)) ethyltrimethylsilane and antitumor agent comprising it as active ingredient
JPS5823626A (ja) * 1981-08-04 1983-02-12 Shin Etsu Chem Co Ltd 抗腫瘍剤
JPS58124719A (ja) * 1982-01-20 1983-07-25 Shin Etsu Chem Co Ltd 抗腫瘍剤

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61155390A (ja) * 1984-12-28 1986-07-15 Sanwa Kagaku Kenkyusho:Kk 新規な有機珪素化合物、その非毒性塩、これらの製法並びにそれを有効成分とする抗腫瘍剤

Also Published As

Publication number Publication date
DE3378913D1 (en) 1989-02-16
EP0109195A2 (en) 1984-05-23
US4560679A (en) 1985-12-24
EP0109195A3 (en) 1985-11-27
EP0109195B1 (en) 1989-01-11
JPH0322394B2 (cg-RX-API-DMAC7.html) 1991-03-26

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