JPS5939829A - ガン壊死因子安定化法 - Google Patents

ガン壊死因子安定化法

Info

Publication number
JPS5939829A
JPS5939829A JP57149890A JP14989082A JPS5939829A JP S5939829 A JPS5939829 A JP S5939829A JP 57149890 A JP57149890 A JP 57149890A JP 14989082 A JP14989082 A JP 14989082A JP S5939829 A JPS5939829 A JP S5939829A
Authority
JP
Japan
Prior art keywords
tnf
polyoxyethylene
solution
fatty acid
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57149890A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0375531B2 (enrdf_load_stackoverflow
Inventor
Hiroshi Hayashi
林 紘
Masanobu Komiya
小宮 雅信
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Sumitomo Pharma Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd, Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Dainippon Pharmaceutical Co Ltd
Priority to JP57149890A priority Critical patent/JPS5939829A/ja
Priority to US06/524,540 priority patent/US4457916A/en
Priority to IT67886/83A priority patent/IT1200970B/it
Priority to DE3331003A priority patent/DE3331003C2/de
Priority to ES525228A priority patent/ES8706446A1/es
Priority to FR8313971A priority patent/FR2532178B1/fr
Priority to GB08323271A priority patent/GB2126588B/en
Publication of JPS5939829A publication Critical patent/JPS5939829A/ja
Publication of JPH0375531B2 publication Critical patent/JPH0375531B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP57149890A 1982-08-31 1982-08-31 ガン壊死因子安定化法 Granted JPS5939829A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP57149890A JPS5939829A (ja) 1982-08-31 1982-08-31 ガン壊死因子安定化法
US06/524,540 US4457916A (en) 1982-08-31 1983-08-19 Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
IT67886/83A IT1200970B (it) 1982-08-31 1983-08-23 Procedimento per stabilizzare un fattore avente effetto necrotizzante sui tumori e soluzione aquosa stabile o polvere che lo contiene
DE3331003A DE3331003C2 (de) 1982-08-31 1983-08-27 Verfahren zur Stabilisierung des Tumor-Nekrose-Faktors und diesen enthaltende wäßrige Lösung oder Pulversubstanz
ES525228A ES8706446A1 (es) 1982-08-31 1983-08-30 Un metodo para preparar una solucion acuosa estable que contiene factor de necrosis de tumores.
FR8313971A FR2532178B1 (fr) 1982-08-31 1983-08-31 Procede pour stabiliser le facteur de necrose tumorale et solution aqueuse ou poudre stables contenant ce facteur
GB08323271A GB2126588B (en) 1982-08-31 1983-08-31 A method for stabilizing tumor necrosis factor and a stable aqueous solution or powder containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57149890A JPS5939829A (ja) 1982-08-31 1982-08-31 ガン壊死因子安定化法

Publications (2)

Publication Number Publication Date
JPS5939829A true JPS5939829A (ja) 1984-03-05
JPH0375531B2 JPH0375531B2 (enrdf_load_stackoverflow) 1991-12-02

Family

ID=15484866

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57149890A Granted JPS5939829A (ja) 1982-08-31 1982-08-31 ガン壊死因子安定化法

Country Status (1)

Country Link
JP (1) JPS5939829A (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166996A1 (en) 1984-06-07 1986-01-08 Asahi Kasei Kogyo Kabushiki Kaisha A method for stabilizing a physiologically active substance produced by recombinant DNA technique and a stable aqueous solution or powder containing the same
JPS63146826A (ja) * 1986-07-18 1988-06-18 Chugai Pharmaceut Co Ltd 安定な顆粒球コロニ−刺激因子含有製剤

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54157818A (en) * 1978-06-02 1979-12-13 Tokyo Tanabe Co Injectionable preparation of chlorethylnitrosourea compound
JPS5640606A (en) * 1979-09-11 1981-04-16 Asahi Chem Ind Co Ltd Preparation of stable drug

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54157818A (en) * 1978-06-02 1979-12-13 Tokyo Tanabe Co Injectionable preparation of chlorethylnitrosourea compound
JPS5640606A (en) * 1979-09-11 1981-04-16 Asahi Chem Ind Co Ltd Preparation of stable drug

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166996A1 (en) 1984-06-07 1986-01-08 Asahi Kasei Kogyo Kabushiki Kaisha A method for stabilizing a physiologically active substance produced by recombinant DNA technique and a stable aqueous solution or powder containing the same
EP0166996B2 (en) 1984-06-07 1994-12-21 Asahi Kasei Kogyo Kabushiki Kaisha A method for stabilizing a physiologically active substance produced by recombinant DNA technique and a stable aqueous solution or powder containing the same
JPS63146826A (ja) * 1986-07-18 1988-06-18 Chugai Pharmaceut Co Ltd 安定な顆粒球コロニ−刺激因子含有製剤

Also Published As

Publication number Publication date
JPH0375531B2 (enrdf_load_stackoverflow) 1991-12-02

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