JPS5922699B2 - プロスタグランジン類似化合物 - Google Patents
プロスタグランジン類似化合物Info
- Publication number
- JPS5922699B2 JPS5922699B2 JP51084038A JP8403876A JPS5922699B2 JP S5922699 B2 JPS5922699 B2 JP S5922699B2 JP 51084038 A JP51084038 A JP 51084038A JP 8403876 A JP8403876 A JP 8403876A JP S5922699 B2 JPS5922699 B2 JP S5922699B2
- Authority
- JP
- Japan
- Prior art keywords
- trans
- compound
- general formula
- reference example
- methyl ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB30072/75A GB1545213A (en) | 1975-07-17 | 1975-07-17 | Prostaglandin analogues |
| GB1865176 | 1976-05-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5227753A JPS5227753A (en) | 1977-03-02 |
| JPS5922699B2 true JPS5922699B2 (ja) | 1984-05-28 |
Family
ID=26253511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51084038A Expired JPS5922699B2 (ja) | 1975-07-17 | 1976-07-16 | プロスタグランジン類似化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4087620A (member.php) |
| JP (1) | JPS5922699B2 (member.php) |
| CA (1) | CA1091662A (member.php) |
| CH (1) | CH616409A5 (member.php) |
| DE (1) | DE2631894C2 (member.php) |
| DK (1) | DK318876A (member.php) |
| FR (1) | FR2317916A1 (member.php) |
| HU (1) | HU176144B (member.php) |
| LU (1) | LU75403A1 (member.php) |
| NL (1) | NL7607800A (member.php) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1568371A (en) * | 1975-12-03 | 1980-05-29 | Allen & Hanburys Ltd | Bicyclo(2,2,1)heptan-2-one-derivatives |
| GB1588196A (en) * | 1977-06-14 | 1981-04-15 | Ono Pharmaceutical Co | Prostaglandin analogues |
| DE2834249A1 (de) * | 1978-08-04 | 1980-02-28 | Hoechst Ag | Neue prostaglandinderivate in der delta 2-11-desoxy-pgf tief 2 bzw. pge tief 2 -reihe |
| US4312994A (en) * | 1981-03-25 | 1982-01-26 | G. D. Searle & Co. | α Chain dienic prostanoic acid derivatives |
| US4983753A (en) * | 1981-05-21 | 1991-01-08 | Floyd Jr Middleton B | Precursors and synthesis of di-(methyl)-16,16-(dimethyl)-11-alpha,15-alpha beta-dihydroxy-9-oxo-2,13-trans,trans-prostadienoates |
| US5166369A (en) * | 1981-05-21 | 1992-11-24 | American Cyanamid Company | Precursors and synthesis of D1-(methyl)-16,16-(dimethyl)-11-alpha, 15-alpha, beta-dihydroxy-9-oxo-2,13,-trans, trans-prostadienoates |
| JPS6130554A (ja) * | 1984-07-23 | 1986-02-12 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤 |
| RU2420316C2 (ru) | 2005-06-03 | 2011-06-10 | Оно Фармасьютикал Ко., Лтд. | Агент для регенерации и/или защиты нервов |
| KR102752118B1 (ko) | 2017-10-31 | 2025-01-08 | 에이지씨 가부시키가이샤 | 프로스타글란딘 유도체의 제조 방법 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4034003A (en) * | 1974-04-11 | 1977-07-05 | Ono Pharmaceutical Co., Ltd. | 15-Cycloalkyl-prostaglandins |
-
1976
- 1976-07-07 US US05/703,158 patent/US4087620A/en not_active Expired - Lifetime
- 1976-07-14 NL NL7607800A patent/NL7607800A/xx not_active Application Discontinuation
- 1976-07-14 HU HU76OO231A patent/HU176144B/hu unknown
- 1976-07-14 CA CA256,941A patent/CA1091662A/en not_active Expired
- 1976-07-14 DK DK318876A patent/DK318876A/da not_active Application Discontinuation
- 1976-07-15 DE DE2631894A patent/DE2631894C2/de not_active Expired
- 1976-07-15 FR FR7621618A patent/FR2317916A1/fr active Granted
- 1976-07-16 CH CH914076A patent/CH616409A5/fr not_active IP Right Cessation
- 1976-07-16 LU LU75403A patent/LU75403A1/xx unknown
- 1976-07-16 JP JP51084038A patent/JPS5922699B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH616409A5 (member.php) | 1980-03-31 |
| JPS5227753A (en) | 1977-03-02 |
| NL7607800A (nl) | 1977-01-19 |
| DE2631894C2 (de) | 1986-01-23 |
| DE2631894A1 (de) | 1977-02-10 |
| US4087620A (en) | 1978-05-02 |
| CA1091662A (en) | 1980-12-16 |
| FR2317916B1 (member.php) | 1981-01-23 |
| FR2317916A1 (fr) | 1977-02-11 |
| DK318876A (da) | 1977-01-18 |
| LU75403A1 (member.php) | 1977-04-04 |
| HU176144B (en) | 1980-12-28 |
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| Publication | Publication Date | Title |
|---|---|---|
| EP0196380B1 (en) | Prostaglandin analogues, processes for their preparation and pharmaceutical compositions containing them | |
| CH628028A5 (de) | Verfahren zur herstellung neuer prostaglandin-analoga mit dreifachbindung zwischen c-13 und c-14. | |
| GB2075976A (en) | 3-hydroxy and 3-oxo-prostaglandin analogues | |
| DE2365035A1 (de) | Prostaglandin-analoge | |
| US4178367A (en) | Prostaglandin I2 analogues | |
| JPS5922699B2 (ja) | プロスタグランジン類似化合物 | |
| DE2347630A1 (de) | Prostaglandin-analoge | |
| CA1066699A (en) | Prostaglandin analogues | |
| US4034003A (en) | 15-Cycloalkyl-prostaglandins | |
| US4149017A (en) | Intermediates for the preparation of bicycloalkyl derivatives of prostaglandins | |
| DE2500451A1 (de) | Prostaglandinanaloge, verfahren zu ihrer herstellung und diese enthaltende arzneimittel | |
| JPS6126970B2 (member.php) | ||
| US4195182A (en) | Trans-Δ2 -prostaglandin analogues | |
| US4180675A (en) | 15-Cycloalkyl-prostaglandin derivatives | |
| US4275075A (en) | 15-cylobutyl-trans-Δ2 -prostaglandin analogues | |
| US4069387A (en) | 16-Chloro-substituted prostaglandins and derivatives thereof | |
| JPS6125010B2 (member.php) | ||
| US4517202A (en) | Prostaglandin analogues | |
| CA1098124A (en) | Process for the preparation of prostaglandin analogues | |
| US4165437A (en) | Δ3 -Prostaglandin analogs | |
| US4473587A (en) | Prostaglandin E1 analogues | |
| US4065632A (en) | 16-Phenoxy and phenylthio prostaglandin derivatives | |
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| DE2626287A1 (de) | Prostanderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittelzusammensetzung | |
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