JPS59139396A - ネオカルチノスタチン複合体の製造方法 - Google Patents

ネオカルチノスタチン複合体の製造方法

Info

Publication number
JPS59139396A
JPS59139396A JP58015075A JP1507583A JPS59139396A JP S59139396 A JPS59139396 A JP S59139396A JP 58015075 A JP58015075 A JP 58015075A JP 1507583 A JP1507583 A JP 1507583A JP S59139396 A JPS59139396 A JP S59139396A
Authority
JP
Japan
Prior art keywords
complex
neocarzinostatin
maleic acid
maleic anhydride
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58015075A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0123480B2 (enrdf_load_stackoverflow
Inventor
Hiroshi Maeda
浩 前田
Ryunosuke Kanamaru
金丸　竜之介
Nakao Ishida
石田　名香雄
Toshihiko Yoshitake
吉武　敏彦
Minoru Ueda
実 上田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAYAKU KK
Kuraray Co Ltd
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
KAYAKU KK
Kuraray Co Ltd
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KAYAKU KK, Kuraray Co Ltd, Yamanouchi Pharmaceutical Co Ltd filed Critical KAYAKU KK
Priority to JP58015075A priority Critical patent/JPS59139396A/ja
Priority to EP83301027A priority patent/EP0087957B1/en
Priority to DE8383301027T priority patent/DE3367921D1/de
Priority to AT83301027T priority patent/ATE23863T1/de
Priority to CA000422497A priority patent/CA1214458A/en
Publication of JPS59139396A publication Critical patent/JPS59139396A/ja
Priority to US06/730,823 priority patent/US4732933A/en
Publication of JPH0123480B2 publication Critical patent/JPH0123480B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
JP58015075A 1982-02-27 1983-01-31 ネオカルチノスタチン複合体の製造方法 Granted JPS59139396A (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP58015075A JPS59139396A (ja) 1983-01-31 1983-01-31 ネオカルチノスタチン複合体の製造方法
EP83301027A EP0087957B1 (en) 1982-02-27 1983-02-25 Neocarzinostatin complexes, a method for producing the same, and an antitumor agent containing said complexes as an active component
DE8383301027T DE3367921D1 (en) 1982-02-27 1983-02-25 Neocarzinostatin complexes, a method for producing the same, and an antitumor agent containing said complexes as an active component
AT83301027T ATE23863T1 (de) 1982-02-27 1983-02-25 Neocarzinostatinkomplexe, verfahren zu ihrer herstellung und antitumormittel, das diese komplexe als aktive komponente enhaelt.
CA000422497A CA1214458A (en) 1982-02-27 1983-02-28 Neocarzinostatin complexes, a method for producing the same, and an antitumor agent containing said complexes as an active component
US06/730,823 US4732933A (en) 1982-02-27 1985-05-06 Neocarzinostatin complexes, a method for producing the same, and an antitumor agent containing said complexes as an active component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58015075A JPS59139396A (ja) 1983-01-31 1983-01-31 ネオカルチノスタチン複合体の製造方法

Publications (2)

Publication Number Publication Date
JPS59139396A true JPS59139396A (ja) 1984-08-10
JPH0123480B2 JPH0123480B2 (enrdf_load_stackoverflow) 1989-05-02

Family

ID=11878729

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58015075A Granted JPS59139396A (ja) 1982-02-27 1983-01-31 ネオカルチノスタチン複合体の製造方法

Country Status (1)

Country Link
JP (1) JPS59139396A (enrdf_load_stackoverflow)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6075432A (ja) * 1983-08-08 1985-04-27 Kuraray Co Ltd ネオカルチノスタチン誘導体及びその製造方法
JPS6485922A (en) * 1986-09-19 1989-03-30 Yamanouchi Pharma Co Ltd Neocarzinostatin derivative composition for noninjection administration
JPH0192212A (ja) * 1987-08-28 1989-04-11 Sandoz Ag 有機コンパウンドの改良
WO1993007175A1 (en) * 1990-06-22 1993-04-15 Mitsuo Yasui Process for producing protein/synthetic polymer complex and said complex produced thereby
WO1993013131A1 (en) * 1991-12-24 1993-07-08 Sumitomo Seika Chemicals Co., Ltd. Process for producing protein-synthetic polymer composite and said composite produced thereby
US5473034A (en) * 1994-03-18 1995-12-05 Hyogo Prefectural Government Method for producing protein-synthetic polymer conjugate and said conjugate produced thereby

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117095A (en) * 1977-03-24 1978-10-13 Hiroshi Maeda Neocarcinostachin derivative and producing process thereof
JPS58149903A (ja) * 1982-02-27 1983-09-06 Kuraray Co Ltd ネオカルチノスタチン複合体の製造法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117095A (en) * 1977-03-24 1978-10-13 Hiroshi Maeda Neocarcinostachin derivative and producing process thereof
JPS58149903A (ja) * 1982-02-27 1983-09-06 Kuraray Co Ltd ネオカルチノスタチン複合体の製造法

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6075432A (ja) * 1983-08-08 1985-04-27 Kuraray Co Ltd ネオカルチノスタチン誘導体及びその製造方法
JPS6485922A (en) * 1986-09-19 1989-03-30 Yamanouchi Pharma Co Ltd Neocarzinostatin derivative composition for noninjection administration
JPH0192212A (ja) * 1987-08-28 1989-04-11 Sandoz Ag 有機コンパウンドの改良
WO1993007175A1 (en) * 1990-06-22 1993-04-15 Mitsuo Yasui Process for producing protein/synthetic polymer complex and said complex produced thereby
WO1993013131A1 (en) * 1991-12-24 1993-07-08 Sumitomo Seika Chemicals Co., Ltd. Process for producing protein-synthetic polymer composite and said composite produced thereby
US5473034A (en) * 1994-03-18 1995-12-05 Hyogo Prefectural Government Method for producing protein-synthetic polymer conjugate and said conjugate produced thereby

Also Published As

Publication number Publication date
JPH0123480B2 (enrdf_load_stackoverflow) 1989-05-02

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