JPS59122954A - Automatic analyzing apparatus - Google Patents

Automatic analyzing apparatus

Info

Publication number
JPS59122954A
JPS59122954A JP23015282A JP23015282A JPS59122954A JP S59122954 A JPS59122954 A JP S59122954A JP 23015282 A JP23015282 A JP 23015282A JP 23015282 A JP23015282 A JP 23015282A JP S59122954 A JPS59122954 A JP S59122954A
Authority
JP
Japan
Prior art keywords
section
analytical
output
correlation
coefficient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP23015282A
Other languages
Japanese (ja)
Inventor
Jugoro Suzuki
鈴木　十五郎
Norihiro Sato
佐藤　教博
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shimadzu Corp
Shimazu Seisakusho KK
Original Assignee
Shimadzu Corp
Shimazu Seisakusho KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corp, Shimazu Seisakusho KK filed Critical Shimadzu Corp
Priority to JP23015282A priority Critical patent/JPS59122954A/en
Publication of JPS59122954A publication Critical patent/JPS59122954A/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

PURPOSE:To enhance analytical reliability, by providing an operation part for calculating the coefficient of correlation of measuring times t0, t1, t2... and measured data A0, A1, A2... and a comparison part for comparing the coefficient of correlation being the output of the operation part and a predetermined reference value. CONSTITUTION:An automatic analytical apparatus consists of an analytical part 2, an operation control part 3 and a recorder part 4. In this case, the analytical part 2 is constituted as is conventional while the operation control part is, for example, a microcomputer system and controls the analytical part 2 according to a conventionally known system. In this case, the coefficient of correlation of measuring times t0, t1, t2... and measuring data A0, A1, A2... is calculated in the operation part while the coefficient of correlation being the output of the operation part and a predetermined reference value are compared in the comparison part and the alarm display of straightness inferiority is performed when output is issued from the comparison part. By this method, the judgement of straightness is performed and, therefore, the reliability of the apparatus is enhanced.

Description

【発明の詳細な説明】 この発明は、自動分析装置に関し、さらに詳しくは、測
定データの直線性についての判断機能を有する自動分析
装置に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an automatic analyzer, and more particularly, to an automatic analyzer having a function of determining linearity of measurement data.

自動分析装置においてレート測定を行う場合、測定時刻
ｔ。、１．．１．、・・・・・・と測定データＡｏ　、
Ａｌ　ｌＡｓ、・・・・・・とが直線関係にあることが
前提となっている。そこで逆に両者に直線性がなければ
、その測定データは信頼できないということになる。When rate measurement is performed in an automatic analyzer, measurement time t. , 1. ．． 1. ,... and measurement data Ao,
It is assumed that Al lAs, . . . have a linear relationship. Conversely, if there is no linearity between the two, the measurement data will be unreliable.

このような観点から、自動分析装置に測定データの直線
性を判断する機能を付設することが提案されている。From this point of view, it has been proposed to add a function to the automatic analyzer to determine the linearity of measurement data.

従来提案されているこの種の装置における直線性の判断
は、たとえば次のように行われている。The linearity of conventionally proposed devices of this type is determined, for example, as follows.

（１）測定区間を第１小区から＄３３小までの３区に等
分する。(1) Divide the measurement area equally into three districts from the 1st district to the $33 district.

（ｌリ　各小回における測定データの積分値を求める。(l) Find the integral value of the measurement data in each small cycle.

（Ｉｔ）　　第２小区の積分値から第１小区の積分値を
引いた差を、第３小区の積分値から第２小区の積分値を
引いた差薔こより除す。(It) The difference obtained by subtracting the integral value of the first sub-section from the integral value of the second sub-section is divided by the difference obtained by subtracting the integral value of the second sub-section from the integral value of the third sub-section.

（１ｖ）商が基準範囲（１，０５〜０．９５　）になけ
れば直線性不良と判定する。(1v) If the quotient is not within the reference range (1.05 to 0.95), it is determined that the linearity is poor.

ところで、ＧＯＴ等の自動分析の場合、血清の濁りなど
に起因してＳ／Ｎ比が悪化し、測定データに平均的なバ
ラツキを生じることがある。この場合の測定データは信
頼性が低下しているので、この判断を行う機能をもつこ
とが自動分析装置としてより望ましいことである。Incidentally, in the case of automatic analysis of GOT and the like, the S/N ratio may deteriorate due to turbidity of serum, etc., and average variation may occur in measurement data. Since the measurement data in this case has low reliability, it is more desirable for an automatic analyzer to have a function for making this determination.

しかし、上記した従来装置による判断は、各ホスにおけ
る積分値を比較するものなので、測定データの平均した
バラツキをチモツクすることができないものである。However, since the above-mentioned conventional device makes a judgment by comparing the integral values of each host, it is not possible to take into account the average variation in the measured data.

この発明は、このような事情に鑑みてなされたものであ
って、測定データのバラツキに関する判断をも含めて直
線性の判断を行いつる機能をもった自動分析装置を提供
することを目的としている。The present invention has been made in view of the above circumstances, and an object of the present invention is to provide an automatic analyzer having a function of making a judgment on linearity, including judgments regarding variations in measurement data. .

以下、図に示す実施例に基いて、この発明を詳説する。Hereinafter, the present invention will be explained in detail based on embodiments shown in the drawings.

なお、これによりこの発明が限定されるものではない。Note that this invention is not limited to this.

第１　’ｆ１．３に示す（１）は、この発明の自動分析
装置の一実施例であって、分析部（２）、演算制御部（
３）およびレコーダ部（４）からなっている。(1) shown in No. 1'f1.3 is an embodiment of the automatic analyzer of the present invention, which includes an analysis section (2), an arithmetic control section (
3) and a recorder section (4).

分析部（２）は、従来公知の自動分析装置の分析部と同
じものである。The analysis section (2) is the same as the analysis section of a conventionally known automatic analyzer.

演算制御部（３）は、たとえばマイクロコンピュータ・
システムであって、従来公知のように分析部（２）を制
御する。それと共に、次のような手順にしたがって測定
データの直線性の判断を行う。The arithmetic control section (3) is, for example, a microcomputer.
The system controls the analyzer (2) in a conventional manner. At the same time, the linearity of the measured data is determined according to the following procedure.

（１）測定区間における測定時刻ｔ。、１．．１．、・
・・・。(1) Measurement time t in the measurement section. , 1. ．． 1. ,・
....

ｔと測定データＡｏ　、Ａｌ、Ａｓ　、・・・・、Ａｎ
を記憶する。t and measurement data Ao, Al, As, ..., An
remember.

（ＩＩ）　　測定時刻と測定データの各々の平均値τ窓
よびαを求める。(II) Determine the measurement time and the average value τ window and α of each of the measurement data.

（Ｉｌ＋）　　次式の演算により相関係数を求める。(Il+) Calculate the correlation coefficient by calculating the following formula.

（ｌｖ）　　ｒが基準値Ｒ（たとえば０．９８　）より
も零に近ければ直線性不良と判定する。(lv) If r is closer to zero than the reference value R (for example, 0.98), it is determined that the linearity is poor.

さらに、直線性不良と判定したときには、レコーダ部（
４）に警告表示”ｌ＆’ｒ４Ｈ”の印字信号を発する。Furthermore, when it is determined that linearity is poor, the recorder section (
4) A print signal of a warning display "l&'r4H" is issued.

レコーダ部（４）は、従来公知のプリンタであって、測
定データの印字や上記警告表示の印字などを行うもので
ある。The recorder section (4) is a conventionally known printer that prints measurement data and the above-mentioned warning display.

以上の説明から理解されるように、この発明は、レート
測定を行う自動分析装置において、測定時刻ｔ。＊　’
ｌ　＋　ｔ２＋　”　”　”　”　”　’と測定データ
ー４０　、ＡＩ　、Ａｆｆｉ　。As understood from the above description, the present invention provides an automatic analyzer that performs rate measurement at measurement time t. ＊'
l + t2+ ” ” ” ” ” ' and measurement data 40, AI, Affi.

・・・・・・の相関係数を求める演算部、その演算部の
出力である相関係数と所定の基準値とを比軸して前者が
後者より零に近いとき出力を発する比較部２よびその比
較部から出力が発された場合に直線性不良の警告表示を
行う警告表示部を具備した自動分析装置を提供するもの
で、相関係数は測定データの平均的１よバラツキをも顕
在化させるから、これにより測定データの平均的なバラ
ツキに関する判断をも含めて直線性の判断がなされるよ
うになり、装置の信頼性を向上することができるように
なる。A computation section that calculates the correlation coefficient of . The present invention provides an automatic analyzer equipped with a warning display section that displays a warning of poor linearity when an output is issued from the comparison section and the comparison section. As a result, the linearity can be judged including the average variation of the measurement data, and the reliability of the apparatus can be improved.

【図面の簡単な説明】[Brief explanation of the drawing]

第１図はこの発明の自動分析装置の一実施例のブロック
図、第２図は第１図に示す装置の直線性。 判断の作動のフローチャートである。 （１）・・・自動分析装置、　（２）・・・分析部、（
３）・・・演算制御部、　　（４）・・・レコーダ部。FIG. 1 is a block diagram of an embodiment of the automatic analyzer of the present invention, and FIG. 2 shows the linearity of the device shown in FIG. It is a flowchart of operation|movement of a judgment. (1)...Automatic analyzer, (2)...Analysis department, (
3)...Arithmetic control section, (4)...Recorder section.

Claims (1)

【特許請求の範囲】[Claims] １、　レート測定を行う自動分析装置において、測定時
刻ｔ。、ｔ□、ｔ２．・・・・・・と測定データＡｏ　
、Ａｌ＋Ａｍ、・・・・・・の相関係数を求める演算部
、その演算部の出力である相関係数と所定の基準値とを
比較して前者が後者より零に近いとき出力を発する比較
部およびその比較部から出力が発された場合に直線性不
良の警告表示を行う警告表示部を具備したことを特徴と
する自動分析装置。1. In an automatic analyzer that performs rate measurement, measurement time t. , t□, t2. ...and measurement data Ao
, Al+Am, . . . A comparison unit that compares the correlation coefficient output from the calculation unit with a predetermined reference value and outputs an output when the former is closer to zero than the latter. An automatic analyzer comprising: a warning display section that displays a warning of poor linearity when an output is issued from the section and the comparison section thereof.
JP23015282A 1982-12-29 1982-12-29 Automatic analyzing apparatus Pending JPS59122954A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP23015282A JPS59122954A (en) 1982-12-29 1982-12-29 Automatic analyzing apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23015282A JPS59122954A (en) 1982-12-29 1982-12-29 Automatic analyzing apparatus

Publications (1)

Publication Number Publication Date
JPS59122954A true JPS59122954A (en) 1984-07-16

Family

ID=16903405

Family Applications (1)

Application Number Title Priority Date Filing Date
JP23015282A Pending JPS59122954A (en) 1982-12-29 1982-12-29 Automatic analyzing apparatus

Country Status (1)

Country Link
JP (1) JPS59122954A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01237453A (en) * 1988-03-18 1989-09-21 Hitachi Ltd Calibration-curve forming method and automatic analyzer using said method
EP0387787A2 (en) * 1989-03-14 1990-09-19 Hitachi, Ltd. Automatic analyzing apparatus and method for clinical examination

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01237453A (en) * 1988-03-18 1989-09-21 Hitachi Ltd Calibration-curve forming method and automatic analyzer using said method
EP0387787A2 (en) * 1989-03-14 1990-09-19 Hitachi, Ltd. Automatic analyzing apparatus and method for clinical examination
US5100622A (en) * 1989-03-14 1992-03-31 Hitachi, Ltd. Automatic analyzing apparatus and method for clinical examination

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