JPS5879997A - ストレプトマイセス属およびその類縁菌に使用するプラスミドｐＥＬ７および関連クロ−ニング・ベクタ− - Google Patents
ストレプトマイセス属およびその類縁菌に使用するプラスミドｐＥＬ７および関連クロ−ニング・ベクタ−Info
- Publication number
- JPS5879997A JPS5879997A JP57184415A JP18441582A JPS5879997A JP S5879997 A JPS5879997 A JP S5879997A JP 57184415 A JP57184415 A JP 57184415A JP 18441582 A JP18441582 A JP 18441582A JP S5879997 A JPS5879997 A JP S5879997A
- Authority
- JP
- Japan
- Prior art keywords
- plasmid
- fragment
- pel7
- treated
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- UZQBOFAUUTZOQE-VSLWXVDYSA-N pikromycin Chemical compound C[C@H]1C[C@@H](C)C(=O)\C=C\[C@@](O)(C)[C@@H](CC)OC(=O)[C@H](C)C(=O)[C@H](C)[C@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)C[C@@H](C)O1 UZQBOFAUUTZOQE-VSLWXVDYSA-N 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000003910 polypeptide antibiotic agent Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229950010526 relomycin Drugs 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 1
- 229960003165 vancomycin Drugs 0.000 description 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000002132 β-lactam antibiotic Substances 0.000 description 1
- 229940124586 β-lactam antibiotics Drugs 0.000 description 1
- 150000003952 β-lactams Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US312446 | 1981-10-19 | ||
| US06/312,446 US4416994A (en) | 1981-10-19 | 1981-10-19 | Plasmid pEL7 and related cloning vectors for use in streptomyces and related organisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5879997A true JPS5879997A (ja) | 1983-05-13 |
Family
ID=23211479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57184415A Pending JPS5879997A (ja) | 1981-10-19 | 1982-10-19 | ストレプトマイセス属およびその類縁菌に使用するプラスミドｐＥＬ７および関連クロ−ニング・ベクタ− |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4416994A (Direct) |
| EP (1) | EP0077650A3 (Direct) |
| JP (1) | JPS5879997A (Direct) |
| AU (1) | AU8942482A (Direct) |
| CA (1) | CA1185547A (Direct) |
| DD (1) | DD208823A5 (Direct) |
| DK (1) | DK460782A (Direct) |
| GR (1) | GR76761B (Direct) |
| IL (1) | IL66988A0 (Direct) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6181787A (ja) * | 1984-09-28 | 1986-04-25 | Nippon Kayaku Co Ltd | 新規なプラスミドベクタ− |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4752574A (en) * | 1982-04-16 | 1988-06-21 | Eli Lilly And Company | Chimeric cloning vectors for use in streptomyces and E. Coli |
| US4513085A (en) * | 1982-10-07 | 1985-04-23 | Eli Lilly And Company | Functionally independent cloning vectors for use in streptomyces |
| US4468462A (en) * | 1982-12-22 | 1984-08-28 | Eli Lilly And Company | Vectors for cloning in streptomyces |
| US4559300A (en) * | 1983-01-18 | 1985-12-17 | Eli Lilly And Company | Method for using an homologous bacillus promoter and associated natural or modified ribosome binding site-containing DNA sequence in streptomyces |
| GB8315579D0 (en) * | 1983-06-07 | 1983-07-13 | Biogen Nv | Streptomyces expression systems |
| US4791064A (en) * | 1983-07-07 | 1988-12-13 | Smithkline Beckman Corporation | Plasmids from nocardia |
| US4667024A (en) * | 1983-07-13 | 1987-05-19 | Smithkline Beckman Corporation | Process for the preparation of purified vancomycin class antibiotics |
| US4643975A (en) * | 1984-01-05 | 1987-02-17 | Eli Lilly And Company | Novel cloning vectors for use in streptomyces, escherichia coli and related organisms |
| US4666846A (en) * | 1984-02-17 | 1987-05-19 | Eli Lilly And Company | Novel cloning vectors containing selectable genetic markers for use in streptomyces and related organisms |
| DE3412093A1 (de) * | 1984-03-31 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Hybridplasmide mit einem streptomyceten- und einem escherichia coli-replicon |
| EP0158872B1 (de) * | 1984-03-31 | 1989-01-18 | Hoechst Aktiengesellschaft | Das Streptomyceten-Plasmid pSG5, Verfahren zu seiner Gewinnung und seine Verwendung |
| US4698307A (en) * | 1984-08-10 | 1987-10-06 | Eli Lilly And Company | Recombinant DNA cloning vectors containing selectable genetic markers for use in streptomyces and related organisms |
| US4683206A (en) * | 1984-08-10 | 1987-07-28 | Eli Lilly And Company | Recombinant DNA cloning vectors containing selectable genetic markers for use in Streptomyces and related organisms |
| US4753886A (en) * | 1984-08-10 | 1988-06-28 | Eli Lilly And Company | Plasmid PHJL210 and related bifunctional cloning vectors for use in streptomycetes |
| US4752577A (en) * | 1984-09-13 | 1988-06-21 | Eli Lilly And Company | Method for using a novel transcriptional- and translational-activating sequence in streptomyces |
| USRE34875E (en) * | 1984-09-25 | 1995-03-14 | Eli Lilly And Company | Method of selecting recombinant DNA-containing streptomyces |
| US4680265A (en) * | 1984-09-25 | 1987-07-14 | Eli Lilly And Company | Method of selecting recombinant DNA-containing streptomyces |
| US4935340A (en) | 1985-06-07 | 1990-06-19 | Eli Lilly And Company | Method of isolating antibiotic biosynthetic genes |
| WO2005021586A2 (en) * | 2003-08-21 | 2005-03-10 | Wisconsin Alumni Research Foundation | Metabolic engineering of viomycin biosynthesis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4273875A (en) * | 1979-03-05 | 1981-06-16 | The Upjohn Company | Plasmid and process of isolating same |
| GB2048894A (en) | 1979-05-11 | 1980-12-17 | Gist Brocades Nv | Plasmid |
| US4343906A (en) * | 1979-08-21 | 1982-08-10 | The Upjohn Company | Hybrid plasmid of pBR322 and Streptomyces plasmid and E. coli containing same |
| US4340674A (en) * | 1980-05-05 | 1982-07-20 | The Upjohn Company | Cointegrate plasmids and their construction from plasmids of Escherichia and Streptomyces |
| US4332898A (en) * | 1980-05-22 | 1982-06-01 | The Upjohn Company | Hybrid plasmid and process of making same |
| US4332900A (en) * | 1980-10-01 | 1982-06-01 | The Upjohn Company | Construction of co-integrate plasmids from plasmids of Streptomyces and Escherichia |
| EP0058002A3 (en) * | 1981-01-26 | 1983-06-29 | The Upjohn Company | Process for stabilising potential plasmid vectors and novel plasmids |
-
1981
- 1981-10-19 US US06/312,446 patent/US4416994A/en not_active Expired - Fee Related
-
1982
- 1982-09-14 CA CA000411404A patent/CA1185547A/en not_active Expired
- 1982-10-14 IL IL66988A patent/IL66988A0/xx unknown
- 1982-10-14 EP EP82305472A patent/EP0077650A3/en not_active Withdrawn
- 1982-10-15 GR GR69551A patent/GR76761B/el unknown
- 1982-10-15 AU AU89424/82A patent/AU8942482A/en not_active Abandoned
- 1982-10-18 DD DD82244078A patent/DD208823A5/de unknown
- 1982-10-18 DK DK460782A patent/DK460782A/da not_active Application Discontinuation
- 1982-10-19 JP JP57184415A patent/JPS5879997A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6181787A (ja) * | 1984-09-28 | 1986-04-25 | Nippon Kayaku Co Ltd | 新規なプラスミドベクタ− |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1185547A (en) | 1985-04-16 |
| IL66988A0 (en) | 1983-02-23 |
| GR76761B (Direct) | 1984-08-31 |
| EP0077650A2 (en) | 1983-04-27 |
| AU8942482A (en) | 1983-04-28 |
| US4416994A (en) | 1983-11-22 |
| DD208823A5 (de) | 1984-04-11 |
| DK460782A (da) | 1983-04-20 |
| EP0077650A3 (en) | 1983-09-21 |
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