JPS58118948A - 分光分析による異常細胞の検出方法及び装置 - Google Patents
分光分析による異常細胞の検出方法及び装置Info
- Publication number
- JPS58118948A JPS58118948A JP57000795A JP79582A JPS58118948A JP S58118948 A JPS58118948 A JP S58118948A JP 57000795 A JP57000795 A JP 57000795A JP 79582 A JP79582 A JP 79582A JP S58118948 A JPS58118948 A JP S58118948A
- Authority
- JP
- Japan
- Prior art keywords
- light
- laser
- wavelength
- analysis
- specimen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002159 abnormal effect Effects 0.000 title claims abstract description 9
- 238000004458 analytical method Methods 0.000 title claims abstract description 8
- 238000000034 method Methods 0.000 title claims description 20
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 8
- 230000001678 irradiating effect Effects 0.000 claims abstract description 4
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 4
- 238000000149 argon plasma sintering Methods 0.000 claims abstract description 3
- 238000004611 spectroscopical analysis Methods 0.000 claims description 9
- 230000005284 excitation Effects 0.000 claims description 6
- 238000010183 spectrum analysis Methods 0.000 claims description 3
- 238000001069 Raman spectroscopy Methods 0.000 claims description 2
- 238000001506 fluorescence spectroscopy Methods 0.000 claims description 2
- 238000001874 polarisation spectroscopy Methods 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 abstract description 22
- 201000011510 cancer Diseases 0.000 abstract description 21
- 238000002189 fluorescence spectrum Methods 0.000 abstract description 7
- 239000002872 contrast media Substances 0.000 abstract description 3
- 230000003595 spectral effect Effects 0.000 abstract description 3
- 238000004040 coloring Methods 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000001360 synchronised effect Effects 0.000 abstract 1
- 210000001835 viscera Anatomy 0.000 abstract 1
- 239000000523 sample Substances 0.000 description 10
- 238000003745 diagnosis Methods 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- 238000001228 spectrum Methods 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 238000002405 diagnostic procedure Methods 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 230000000704 physical effect Effects 0.000 description 3
- 241000270281 Coluber constrictor Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- OQZCSNDVOWYALR-UHFFFAOYSA-N flurochloridone Chemical compound FC(F)(F)C1=CC=CC(N2C(C(Cl)C(CCl)C2)=O)=C1 OQZCSNDVOWYALR-UHFFFAOYSA-N 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000010287 polarization Effects 0.000 description 2
- 230000002123 temporal effect Effects 0.000 description 2
- 241000157282 Aesculus Species 0.000 description 1
- 238000011735 C3H mouse Methods 0.000 description 1
- UJKPHYRXOLRVJJ-MLSVHJFASA-N CC(O)C1=C(C)/C2=C/C3=N/C(=C\C4=C(CCC(O)=O)C(C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C)=C4C(C)O)/C(CCC(O)=O)=C3C Chemical class CC(O)C1=C(C)/C2=C/C3=N/C(=C\C4=C(CCC(O)=O)C(C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C)=C4C(C)O)/C(CCC(O)=O)=C3C UJKPHYRXOLRVJJ-MLSVHJFASA-N 0.000 description 1
- 241000218691 Cupressaceae Species 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 125000002015 acyclic group Chemical group 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 238000013399 early diagnosis Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000010181 horse chestnut Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000683 nonmetastatic effect Effects 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000012306 spectroscopic technique Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000010184 time-resolved spectral analysis Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
Landscapes
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57000795A JPS58118948A (ja) | 1982-01-06 | 1982-01-06 | 分光分析による異常細胞の検出方法及び装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57000795A JPS58118948A (ja) | 1982-01-06 | 1982-01-06 | 分光分析による異常細胞の検出方法及び装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58118948A true JPS58118948A (ja) | 1983-07-15 |
| JPH0222331B2 JPH0222331B2 (show.php) | 1990-05-18 |
Family
ID=11483610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57000795A Granted JPS58118948A (ja) | 1982-01-06 | 1982-01-06 | 分光分析による異常細胞の検出方法及び装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58118948A (show.php) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63191043A (ja) * | 1987-02-03 | 1988-08-08 | Omron Tateisi Electronics Co | 細胞分析装置 |
| JP2004506919A (ja) * | 2000-08-25 | 2004-03-04 | アムニス コーポレイション | 細胞などの小さな移動物体の速度測定 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5087395A (show.php) * | 1973-11-28 | 1975-07-14 | ||
| JPS5470094A (en) * | 1977-11-15 | 1979-06-05 | Shimadzu Corp | Fluorescent polarization dissolution apparatus |
-
1982
- 1982-01-06 JP JP57000795A patent/JPS58118948A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5087395A (show.php) * | 1973-11-28 | 1975-07-14 | ||
| JPS5470094A (en) * | 1977-11-15 | 1979-06-05 | Shimadzu Corp | Fluorescent polarization dissolution apparatus |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63191043A (ja) * | 1987-02-03 | 1988-08-08 | Omron Tateisi Electronics Co | 細胞分析装置 |
| JP2004506919A (ja) * | 2000-08-25 | 2004-03-04 | アムニス コーポレイション | 細胞などの小さな移動物体の速度測定 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0222331B2 (show.php) | 1990-05-18 |
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