JPS5798272A - Preparation of 5-(2-cyanoethyl)-2,4-imidazolidinedione - Google Patents
Preparation of 5-(2-cyanoethyl)-2,4-imidazolidinedioneInfo
- Publication number
- JPS5798272A JPS5798272A JP17514180A JP17514180A JPS5798272A JP S5798272 A JPS5798272 A JP S5798272A JP 17514180 A JP17514180 A JP 17514180A JP 17514180 A JP17514180 A JP 17514180A JP S5798272 A JPS5798272 A JP S5798272A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- oxobutyronitrile
- ammonia
- preparation
- carbon dioxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To prepare the titled substance useful as an intermediate for glutamic acid, etc., in high yield, by reacting 4-oxobutyronitrile, ammonia, carbon dioxide, and hydrocyanic acid, etc. using a specific amount of water as a solvent, in two steps, i.e. at low temperature and high temperaure.
CONSTITUTION: In the preparation of the titled substance by the BUCHERER- BERGS reaction of 4-oxobutyronitrile and/or 2-hydroxypentane dinitrile (the component A), ammonia and/or an ammonium salt, carbon dioxide and/or a carbonate, and hydrocyanic acid and/or its salt, the reaction is carried out using 90W600mol (pref. 90W350mol) of water as a solvent based on 1mol of the component (A), first at room temperature W40°C for 0.5W5hr, and then at 45W110°C for 15minW10hr.
EFFECT: The by-product can be easily and almost completely converted to the objective compound by the acid treatment after the reaction.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17514180A JPS5798272A (en) | 1980-12-10 | 1980-12-10 | Preparation of 5-(2-cyanoethyl)-2,4-imidazolidinedione |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17514180A JPS5798272A (en) | 1980-12-10 | 1980-12-10 | Preparation of 5-(2-cyanoethyl)-2,4-imidazolidinedione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5798272A true JPS5798272A (en) | 1982-06-18 |
| JPH0114227B2 JPH0114227B2 (en) | 1989-03-10 |
Family
ID=15990997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17514180A Granted JPS5798272A (en) | 1980-12-10 | 1980-12-10 | Preparation of 5-(2-cyanoethyl)-2,4-imidazolidinedione |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5798272A (en) |
-
1980
- 1980-12-10 JP JP17514180A patent/JPS5798272A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0114227B2 (en) | 1989-03-10 |
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