JPS5793964A - Manufacture of 5-methyl-4-imidazole carboxylic acid ester - Google Patents
Manufacture of 5-methyl-4-imidazole carboxylic acid esterInfo
- Publication number
- JPS5793964A JPS5793964A JP56160027A JP16002781A JPS5793964A JP S5793964 A JPS5793964 A JP S5793964A JP 56160027 A JP56160027 A JP 56160027A JP 16002781 A JP16002781 A JP 16002781A JP S5793964 A JPS5793964 A JP S5793964A
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- manufacture
- carboxylic acid
- acid ester
- imidazole carboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- ULHLTDXPKWELHQ-UHFFFAOYSA-N 5-methyl-imidazole-4-carboxylic acid Chemical compound CC=1NC=NC=1C(O)=O ULHLTDXPKWELHQ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- WDJHALXBUFZDSR-UHFFFAOYSA-N acetoacetic acid Chemical class CC(=O)CC(O)=O WDJHALXBUFZDSR-UHFFFAOYSA-N 0.000 abstract 1
- CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 abstract 1
- 229960001380 cimetidine Drugs 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/195,278 US4328349A (en) | 1980-10-08 | 1980-10-08 | Process for preparing 5-methyl-4-imidazolecarboxylic acid esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5793964A true JPS5793964A (en) | 1982-06-11 |
Family
ID=22720775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56160027A Pending JPS5793964A (en) | 1980-10-08 | 1981-10-06 | Manufacture of 5-methyl-4-imidazole carboxylic acid ester |
Country Status (10)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4499283A (en) * | 1982-06-28 | 1985-02-12 | American Cyanamid Company | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4-(3H)-ones |
| US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
| US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
| US5210079A (en) * | 1988-01-07 | 1993-05-11 | E. I. Du Pont De Nemours And Company | Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists |
| US5354867A (en) * | 1988-12-06 | 1994-10-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
| HU215834B (hu) * | 1989-06-30 | 1999-04-28 | E. I. Du Pont De Nemours And Co. | Eljárás aromás csoporttal szubsztituált imidazolszármazékok, valamint ezeket hatóanyagként tartalmazó gyógyszerkészítmények előállítására |
| WO1991009022A1 (en) * | 1989-12-12 | 1991-06-27 | Novosibirsky Institut Organicheskoi Khimii Sibirskogo Otdelenia Akademii Nauk Sssr | 2,2-dialkyl-2h-imidazole-1-oxides and method of obtaining them |
| WO1991011439A1 (en) * | 1990-01-24 | 1991-08-08 | Novosibirsky Institut Organicheskoi Khimii Sibirskogo Otdelenia Akademii Nauk Sssr | Derivatives of 4-amino-3-imidazoline-1-oxyl and method of preparation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5283373A (en) * | 1975-12-24 | 1977-07-12 | Basf Ag | 44methylimidazolee55 carboxylic acid isopropyl ester and preparation thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1341375A (en) * | 1969-11-19 | 1973-12-19 | Smith Kline French Lab | Aminoalkylimidazoles and process for their production |
| US3715365A (en) * | 1971-02-08 | 1973-02-06 | Jefferson Chem Co Inc | Imidazole synthesis |
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
| GB1401284A (en) * | 1971-11-13 | 1975-07-16 | Beecham Group Ltd | Imidazole insecticides |
| US4134983A (en) * | 1975-03-03 | 1979-01-16 | Merck & Co., Inc. | 3-amino-2-or-propoxyaryl substituted imidazoles |
-
1980
- 1980-10-08 US US06/195,278 patent/US4328349A/en not_active Expired - Lifetime
-
1981
- 1981-09-09 DK DK399681A patent/DK399681A/da not_active Application Discontinuation
- 1981-10-06 JP JP56160027A patent/JPS5793964A/ja active Pending
- 1981-10-07 AT AT81304640T patent/ATE26265T1/de not_active IP Right Cessation
- 1981-10-07 DE DE8181304640T patent/DE3176061D1/de not_active Expired
- 1981-10-07 GR GR66219A patent/GR75373B/el unknown
- 1981-10-07 EP EP81304640A patent/EP0049638B1/en not_active Expired
- 1981-10-07 KR KR1019810003790A patent/KR880001316B1/ko not_active Expired
- 1981-10-07 IE IE2346/81A patent/IE52370B1/en unknown
- 1981-10-07 YU YU02417/81A patent/YU241781A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5283373A (en) * | 1975-12-24 | 1977-07-12 | Basf Ag | 44methylimidazolee55 carboxylic acid isopropyl ester and preparation thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| YU241781A (en) | 1984-02-29 |
| IE52370B1 (en) | 1987-09-30 |
| KR880001316B1 (ko) | 1988-07-23 |
| US4328349A (en) | 1982-05-04 |
| EP0049638A1 (en) | 1982-04-14 |
| DK399681A (da) | 1982-04-09 |
| ATE26265T1 (de) | 1987-04-15 |
| IE812346L (en) | 1982-04-08 |
| KR830007574A (ko) | 1983-11-04 |
| EP0049638B1 (en) | 1987-04-01 |
| GR75373B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-07-13 |
| DE3176061D1 (de) | 1987-05-07 |
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