JPS5793961A - Novel 4-quinoline methane derivative and manufacture - Google Patents

Novel 4-quinoline methane derivative and manufacture

Info

Publication number
JPS5793961A
JPS5793961A JP56161085A JP16108581A JPS5793961A JP S5793961 A JPS5793961 A JP S5793961A JP 56161085 A JP56161085 A JP 56161085A JP 16108581 A JP16108581 A JP 16108581A JP S5793961 A JPS5793961 A JP S5793961A
Authority
JP
Japan
Prior art keywords
novel
manufacture
methane derivative
quinoline methane
quinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56161085A
Other languages
English (en)
Other versions
JPH0261473B2 (ja
Inventor
Hitsukuman Etsukuharuto
Eezaa Haintsuugiyuntaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JPS5793961A publication Critical patent/JPS5793961A/ja
Publication of JPH0261473B2 publication Critical patent/JPH0261473B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP56161085A 1980-10-11 1981-10-12 Novel 4-quinoline methane derivative and manufacture Granted JPS5793961A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803038504 DE3038504A1 (de) 1980-10-11 1980-10-11 Neue 4-chinolinmethanderivate, ihre herstellung und verwendung zur darstellung von substanzen mit arzneimittelwirkung

Publications (2)

Publication Number Publication Date
JPS5793961A true JPS5793961A (en) 1982-06-11
JPH0261473B2 JPH0261473B2 (ja) 1990-12-20

Family

ID=6114192

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56161085A Granted JPS5793961A (en) 1980-10-11 1981-10-12 Novel 4-quinoline methane derivative and manufacture

Country Status (7)

Country Link
US (1) US4429130A (ja)
EP (1) EP0049776B1 (ja)
JP (1) JPS5793961A (ja)
DE (2) DE3038504A1 (ja)
DK (1) DK169435B1 (ja)
GR (1) GR74977B (ja)
HU (1) HU183612B (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59110678A (ja) * 1982-12-02 1984-06-26 アルカロイダ・ベギエスゼテイ・ギヤル 新規クロロメチルキノリン誘導体ならびにその製造法
JPS59155362A (ja) * 1982-12-11 1984-09-04 アルカロイダ・ベギエスゼテイ・ギヤル 弗素化メチルキノリン誘導体およびその製造法
DE112016007146T5 (de) 2016-09-20 2019-05-02 Mitsubishi Electric Corporation Störungsidentifizierungsvorrichtung und Störungsidentifizierungsverfahren

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE55387T1 (de) * 1983-10-07 1990-08-15 Hoffmann La Roche Mefloquin-hydrochlorid.
CH667267A5 (de) * 1986-05-26 1988-09-30 Mepha Ag Verfahren zur herstellung von (2,8-bis-(trifluormethyl)-4-chinolyl)-2-pyridinyl-methanon.
HUT54363A (en) * 1989-07-25 1991-02-28 Alkaloida Vegyeszeti Gyar Process for producing pyridyl-methyl-quinolin derivatives
GB9819382D0 (en) * 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I
US6500955B1 (en) 2001-02-02 2002-12-31 National Institute Of Pharmaceutical Education And Research One pot synthesis of [2,8-Bis (trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone, a mefloquine intermediate

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59110678A (ja) * 1982-12-02 1984-06-26 アルカロイダ・ベギエスゼテイ・ギヤル 新規クロロメチルキノリン誘導体ならびにその製造法
JPS59155362A (ja) * 1982-12-11 1984-09-04 アルカロイダ・ベギエスゼテイ・ギヤル 弗素化メチルキノリン誘導体およびその製造法
JPH0568465B2 (ja) * 1982-12-11 1993-09-29 Alkaloida Vegyeszeti Gyar
DE112016007146T5 (de) 2016-09-20 2019-05-02 Mitsubishi Electric Corporation Störungsidentifizierungsvorrichtung und Störungsidentifizierungsverfahren

Also Published As

Publication number Publication date
EP0049776A2 (de) 1982-04-21
DE3038504A1 (de) 1982-06-03
GR74977B (ja) 1984-07-12
JPH0261473B2 (ja) 1990-12-20
EP0049776B1 (de) 1985-07-31
DE3171591D1 (en) 1985-09-05
EP0049776A3 (en) 1982-05-19
US4429130A (en) 1984-01-31
DK448981A (da) 1982-04-12
HU183612B (en) 1984-05-28
DK169435B1 (da) 1994-10-31

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