JPS5777697A - Physiologically active substance nsq - Google Patents

Physiologically active substance nsq

Info

Publication number
JPS5777697A
JPS5777697A JP55155486A JP15548680A JPS5777697A JP S5777697 A JPS5777697 A JP S5777697A JP 55155486 A JP55155486 A JP 55155486A JP 15548680 A JP15548680 A JP 15548680A JP S5777697 A JPS5777697 A JP S5777697A
Authority
JP
Japan
Prior art keywords
agent
various kinds
extracted
substance
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55155486A
Other languages
English (en)
Other versions
JPS6325600B2 (ja
Inventor
Jinemon Konishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIHON ZOUKI SEIYAKU KK
Nippon Zoki Pharmaceutical Co Ltd
Original Assignee
NIHON ZOUKI SEIYAKU KK
Nippon Zoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIHON ZOUKI SEIYAKU KK, Nippon Zoki Pharmaceutical Co Ltd filed Critical NIHON ZOUKI SEIYAKU KK
Priority to JP55155486A priority Critical patent/JPS5777697A/ja
Publication of JPS5777697A publication Critical patent/JPS5777697A/ja
Publication of JPS6325600B2 publication Critical patent/JPS6325600B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
JP55155486A 1980-11-04 1980-11-04 Physiologically active substance nsq Granted JPS5777697A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55155486A JPS5777697A (en) 1980-11-04 1980-11-04 Physiologically active substance nsq

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55155486A JPS5777697A (en) 1980-11-04 1980-11-04 Physiologically active substance nsq

Publications (2)

Publication Number Publication Date
JPS5777697A true JPS5777697A (en) 1982-05-15
JPS6325600B2 JPS6325600B2 (ja) 1988-05-26

Family

ID=15607090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55155486A Granted JPS5777697A (en) 1980-11-04 1980-11-04 Physiologically active substance nsq

Country Status (1)

Country Link
JP (1) JPS5777697A (ja)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6429389A (en) * 1987-07-23 1989-01-31 Nippon Zoki Pharmaceutical Co Novel physiologically active substance and production thereof
JPH0228115A (ja) * 1988-04-30 1990-01-30 Nippon Zoki Pharmaceut Co Ltd 生理活性物質及び該物質を含有する医薬組成物
US5534509A (en) * 1993-03-19 1996-07-09 Nippon Zoki Pharmaceutical Co., Ltd. Pharmaceutical composition regulating function of a living body
US5560935A (en) * 1993-09-28 1996-10-01 Nippon Zoki Pharmaceutical Co., Ltd. Physiologically active substances extracted from activated tissues
US5599683A (en) * 1993-08-06 1997-02-04 Nippon Zoki Pharmaceutical Co., Ltd. Method for measuring production activity of test substance towards FXIIa
US5648228A (en) * 1993-08-06 1997-07-15 Nippon Zoki Pharmaceutical Co., Ltd. Measuring activity toward production of activated blood coagulation factor XII, plasma kallikrein or bradykinin using reconstituted kallikrein-kinin system
EP0852950A1 (en) * 1997-01-08 1998-07-15 Nippon Zoki Pharmaceutical Co., Ltd. Nitrogen monoxide production suppressor
JP2001058949A (ja) * 1999-08-20 2001-03-06 Fujimoto Brothers:Kk 抗ショック剤
US6365192B1 (en) 1999-04-15 2002-04-02 Nippon Zoki Pharmaceutical Co., Ltd. Bioactivating substance
US6541041B1 (en) 1997-11-28 2003-04-01 Nippon Zoki Pharmaceutical Co., Ltd. Crude drug extracts, and methods for making and standardizing same
US6726932B2 (en) 2000-02-18 2004-04-27 Nippon Zoki Pharmaceutical Co., Ltd. Fatty acid-containing composition
US6913900B2 (en) 2001-08-29 2005-07-05 Nippon Zoki Pharmaceutical Co., Ltd. Plasma prekallikrein activation and kallikrein production assay
US8293280B2 (en) 2004-12-17 2012-10-23 Nippon Zoki Pharmaceutical Co., Ltd. Method for treatment of HIV infection
US8568789B2 (en) 2004-12-01 2013-10-29 Nippon Zoki Pharmaceutical Co., Ltd. Dried product and a process for manufacturing the product
JP2017505316A (ja) * 2014-02-07 2017-02-16 ニューロクライン バイオサイエンシーズ，インコーポレイテッド 抗精神病薬物およびｖｍａｔ２阻害剤を含む医薬組成物およびその使用
US9884077B2 (en) 2013-04-30 2018-02-06 Nippon Zoki Pharmaceutical Co., Ltd. Extract and preparation containing said extract
US10844058B2 (en) 2015-10-30 2020-11-24 Neurocrine Biosciences, Inc. Valbenazine salts and polymorphs thereof
US10857137B2 (en) 2017-01-27 2020-12-08 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10857148B2 (en) 2017-10-10 2020-12-08 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10906902B2 (en) 2015-12-23 2021-02-02 Neurocrine Biosciences, Inc. Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)
US10940141B1 (en) 2019-08-23 2021-03-09 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10993941B2 (en) 2017-10-10 2021-05-04 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11026931B2 (en) 2018-08-15 2021-06-08 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11026939B2 (en) 2017-09-21 2021-06-08 Neurocrine Biosciences, Inc. High dosage valbenazine formulation and compositions, methods, and kits related thereto

Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6429389A (en) * 1987-07-23 1989-01-31 Nippon Zoki Pharmaceutical Co Novel physiologically active substance and production thereof
JPH0228115A (ja) * 1988-04-30 1990-01-30 Nippon Zoki Pharmaceut Co Ltd 生理活性物質及び該物質を含有する医薬組成物
US5658896A (en) * 1993-03-19 1997-08-19 Nippon Zoki Pharmaceutical Co., Ltd. Pharmaceutical composition regulating function of a living body
US5534509A (en) * 1993-03-19 1996-07-09 Nippon Zoki Pharmaceutical Co., Ltd. Pharmaceutical composition regulating function of a living body
US5807951A (en) * 1993-03-19 1998-09-15 Nippon Zoki Pharmaceutical Co., Ltd. Pharmaceutical composition regulating function of a living body
US5599683A (en) * 1993-08-06 1997-02-04 Nippon Zoki Pharmaceutical Co., Ltd. Method for measuring production activity of test substance towards FXIIa
US5648228A (en) * 1993-08-06 1997-07-15 Nippon Zoki Pharmaceutical Co., Ltd. Measuring activity toward production of activated blood coagulation factor XII, plasma kallikrein or bradykinin using reconstituted kallikrein-kinin system
US5560935A (en) * 1993-09-28 1996-10-01 Nippon Zoki Pharmaceutical Co., Ltd. Physiologically active substances extracted from activated tissues
EP0852950A1 (en) * 1997-01-08 1998-07-15 Nippon Zoki Pharmaceutical Co., Ltd. Nitrogen monoxide production suppressor
US6051613A (en) * 1997-01-08 2000-04-18 Nippon Zoki Pharmaceutical Co., Ltd. Nitrogen monoxide production suppressor
US6541041B1 (en) 1997-11-28 2003-04-01 Nippon Zoki Pharmaceutical Co., Ltd. Crude drug extracts, and methods for making and standardizing same
US6576241B2 (en) 1997-11-28 2003-06-10 Nippon Zoki Pharmaceutical Co., Ltd. Crude drug extracts, and methods for making and standardizing same
US6365192B1 (en) 1999-04-15 2002-04-02 Nippon Zoki Pharmaceutical Co., Ltd. Bioactivating substance
JP2001058949A (ja) * 1999-08-20 2001-03-06 Fujimoto Brothers:Kk 抗ショック剤
US6726932B2 (en) 2000-02-18 2004-04-27 Nippon Zoki Pharmaceutical Co., Ltd. Fatty acid-containing composition
US6913900B2 (en) 2001-08-29 2005-07-05 Nippon Zoki Pharmaceutical Co., Ltd. Plasma prekallikrein activation and kallikrein production assay
US8568789B2 (en) 2004-12-01 2013-10-29 Nippon Zoki Pharmaceutical Co., Ltd. Dried product and a process for manufacturing the product
US8293280B2 (en) 2004-12-17 2012-10-23 Nippon Zoki Pharmaceutical Co., Ltd. Method for treatment of HIV infection
US9884077B2 (en) 2013-04-30 2018-02-06 Nippon Zoki Pharmaceutical Co., Ltd. Extract and preparation containing said extract
JP2017505316A (ja) * 2014-02-07 2017-02-16 ニューロクライン バイオサイエンシーズ，インコーポレイテッド 抗精神病薬物およびｖｍａｔ２阻害剤を含む医薬組成物およびその使用
US10844058B2 (en) 2015-10-30 2020-11-24 Neurocrine Biosciences, Inc. Valbenazine salts and polymorphs thereof
US10851103B2 (en) 2015-10-30 2020-12-01 Neurocrine Biosciences, Inc. Valbenazine salts and polymorphs thereof
US10851104B2 (en) 2015-10-30 2020-12-01 Neurocrine Biosciences, Inc. Valbenazine salts and polymorphs thereof
US10919892B2 (en) 2015-12-23 2021-02-16 Neurocrine Biosciences, Inc. Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)
US10906902B2 (en) 2015-12-23 2021-02-02 Neurocrine Biosciences, Inc. Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)
US10906903B2 (en) 2015-12-23 2021-02-02 Neurocrine Biosciences, Inc. Synthetic methods for preparation of (S)-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1,-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate)
US10857137B2 (en) 2017-01-27 2020-12-08 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10874648B2 (en) 2017-01-27 2020-12-29 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10912771B1 (en) 2017-01-27 2021-02-09 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11439629B2 (en) 2017-01-27 2022-09-13 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10952997B2 (en) 2017-01-27 2021-03-23 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11040029B2 (en) 2017-01-27 2021-06-22 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11026939B2 (en) 2017-09-21 2021-06-08 Neurocrine Biosciences, Inc. High dosage valbenazine formulation and compositions, methods, and kits related thereto
US11311532B2 (en) 2017-09-21 2022-04-26 Neurocrine Biosciences, Inc. High dosage valbenazine formulation and compositions, methods, and kits related thereto
US10857148B2 (en) 2017-10-10 2020-12-08 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10993941B2 (en) 2017-10-10 2021-05-04 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11654142B2 (en) 2017-10-10 2023-05-23 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US11026931B2 (en) 2018-08-15 2021-06-08 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
US10940141B1 (en) 2019-08-23 2021-03-09 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors

Also Published As

Publication number Publication date
JPS6325600B2 (ja) 1988-05-26

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