JPS5758686A - Aminodesoxy-1,4;3,6-dianhydrohexitol nitrate, preparation and drug composition - Google Patents

Aminodesoxy-1,4;3,6-dianhydrohexitol nitrate, preparation and drug composition

Info

Publication number
JPS5758686A
JPS5758686A JP56116324A JP11632481A JPS5758686A JP S5758686 A JPS5758686 A JP S5758686A JP 56116324 A JP56116324 A JP 56116324A JP 11632481 A JP11632481 A JP 11632481A JP S5758686 A JPS5758686 A JP S5758686A
Authority
JP
Japan
Prior art keywords
aminodesoxy
preparation
dianhydrohexitol
nitrate
drug composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56116324A
Other languages
English (en)
Other versions
JPH0256359B2 (ja
Inventor
Kuretsushinku Kurausu
Sundaa Chiyatajii Shiyuyamu
Ruisu Gabaaru Berunaaru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DOKUTAA UIRUMAARU SHIYUWAABE
Dr Willmar Schwabe GmbH and Co KG
Original Assignee
DOKUTAA UIRUMAARU SHIYUWAABE
Dr Willmar Schwabe GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DOKUTAA UIRUMAARU SHIYUWAABE, Dr Willmar Schwabe GmbH and Co KG filed Critical DOKUTAA UIRUMAARU SHIYUWAABE
Publication of JPS5758686A publication Critical patent/JPS5758686A/ja
Publication of JPH0256359B2 publication Critical patent/JPH0256359B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
JP56116324A 1980-07-25 1981-07-24 Aminodesoxy-1,4;3,6-dianhydrohexitol nitrate, preparation and drug composition Granted JPS5758686A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3028340A DE3028340C2 (de) 1980-07-25 1980-07-25 Amino-desoxy-1.4;3.6-dianhydro-hexit-nitrate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
JPS5758686A true JPS5758686A (en) 1982-04-08
JPH0256359B2 JPH0256359B2 (ja) 1990-11-29

Family

ID=6108144

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56116324A Granted JPS5758686A (en) 1980-07-25 1981-07-24 Aminodesoxy-1,4;3,6-dianhydrohexitol nitrate, preparation and drug composition

Country Status (7)

Country Link
US (1) US4363805A (ja)
EP (1) EP0044940B1 (ja)
JP (1) JPS5758686A (ja)
AT (1) ATE9472T1 (ja)
CA (1) CA1244411A (ja)
DE (1) DE3028340C2 (ja)
ES (1) ES8403910A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02211699A (ja) * 1989-02-10 1990-08-22 Asia Electron Inc 電子機器の冷却機構
JPH02211700A (ja) * 1989-02-10 1990-08-22 Asia Electron Inc 電子機器の冷却機構
JPH04221898A (ja) * 1990-03-19 1992-08-12 Internatl Business Mach Corp <Ibm> 電子素子組立体
JP2007502831A (ja) * 2003-08-20 2007-02-15 ニトロメッド インコーポレーティッド ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3602067A1 (de) * 1986-01-24 1987-07-30 Mack Chem Pharm 2,6-dioxabicyclo(3.3.0)octan-derivate, ihre herstellung und verwendung als arzneimittel
DE3741005A1 (de) * 1987-12-03 1989-06-15 Mack Chem Pharm Aminopropanol-derivate von 1,4:3,6-dianhydro-hexit-nitraten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4891373A (en) * 1988-11-23 1990-01-02 Pfizer Inc. Aminopropanol derivatives of 1,4:3,6-dianhydrohexitol nitrates, processes for their preparation and their use as medicaments
CA2014520C (en) * 1989-04-17 1996-07-16 Fumio Suzuki Hexitol derivatives
JPH0435359U (ja) * 1990-07-20 1992-03-24
JPH0435361U (ja) * 1990-07-20 1992-03-24
US5120737A (en) * 1990-09-28 1992-06-09 Kyowa Hakko Kogyo Co., Ltd. Hexitol derivatives
US20080300292A1 (en) * 2004-11-08 2008-12-04 Nitromed, Inc Nitrosated and Nitrosylated Compounds, Compositions and Methods for the Treatment of Ophthalmic Disorders
US20080021209A1 (en) * 2006-06-01 2008-01-24 New Jersey Institute Of Technology Ethers of bisanhydrohexitols
US20160016969A1 (en) * 2013-03-05 2016-01-21 Archer Daniels Midland Company Isohexide monotriflates and process for synthesis thereof
MA44037B1 (fr) * 2016-06-06 2020-03-31 Arena Pharm Inc Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci
US10501471B1 (en) * 2018-11-04 2019-12-10 John F. Schmedtje, Jr. Compounds useful for treating cardiovascular diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886186A (en) * 1971-04-29 1975-05-27 American Home Prod Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol
AU465217B2 (en) * 1971-04-29 1975-09-18 American Home Products Corporation Mononitrte esters of 1,4:3, 6-dianhydro-d-glucitol
US4065488A (en) * 1977-02-24 1977-12-27 American Home Products Corporation Process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate
DE2903927C2 (de) * 1979-02-02 1981-03-12 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Verfahren zur selektiven Herstellung von Isosorbid-5-nitrat
DE2903983A1 (de) * 1979-02-02 1980-09-04 Sanol Arznei Schwarz Gmbh Verfahren zur selektiven herstellung von isosorbid-2-nitrat

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02211699A (ja) * 1989-02-10 1990-08-22 Asia Electron Inc 電子機器の冷却機構
JPH02211700A (ja) * 1989-02-10 1990-08-22 Asia Electron Inc 電子機器の冷却機構
JPH04221898A (ja) * 1990-03-19 1992-08-12 Internatl Business Mach Corp <Ibm> 電子素子組立体
JP2007502831A (ja) * 2003-08-20 2007-02-15 ニトロメッド インコーポレーティッド ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法

Also Published As

Publication number Publication date
ATE9472T1 (de) 1984-10-15
EP0044940B1 (de) 1984-09-19
JPH0256359B2 (ja) 1990-11-29
ES503884A0 (es) 1984-04-01
EP0044940A1 (de) 1982-02-03
ES8403910A1 (es) 1984-04-01
US4363805A (en) 1982-12-14
CA1244411A (en) 1988-11-08
DE3028340C2 (de) 1987-02-05
DE3028340A1 (de) 1982-02-25

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