JPS5745200A - Anti-inflammatory steroid and pharmacological composition containing the same - Google Patents

Anti-inflammatory steroid and pharmacological composition containing the same

Info

Publication number
JPS5745200A
JPS5745200A JP56108755A JP10875581A JPS5745200A JP S5745200 A JPS5745200 A JP S5745200A JP 56108755 A JP56108755 A JP 56108755A JP 10875581 A JP10875581 A JP 10875581A JP S5745200 A JPS5745200 A JP S5745200A
Authority
JP
Japan
Prior art keywords
compound
formula
alkyl
methyl
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56108755A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6411037B2 (enrdf_load_stackoverflow
Inventor
Sutefuan Boodaa Nikorasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of JPS5745200A publication Critical patent/JPS5745200A/ja
Publication of JPS6411037B2 publication Critical patent/JPS6411037B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56108755A 1980-07-10 1981-07-10 Anti-inflammatory steroid and pharmacological composition containing the same Granted JPS5745200A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16845380A 1980-07-10 1980-07-10

Publications (2)

Publication Number Publication Date
JPS5745200A true JPS5745200A (en) 1982-03-13
JPS6411037B2 JPS6411037B2 (enrdf_load_stackoverflow) 1989-02-23

Family

ID=22611544

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56108755A Granted JPS5745200A (en) 1980-07-10 1981-07-10 Anti-inflammatory steroid and pharmacological composition containing the same

Country Status (4)

Country Link
JP (1) JPS5745200A (enrdf_load_stackoverflow)
BE (1) BE889563A (enrdf_load_stackoverflow)
SU (1) SU1318169A3 (enrdf_load_stackoverflow)
ZA (1) ZA814440B (enrdf_load_stackoverflow)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058999A (ja) * 1983-08-18 1985-04-05 チバ‐ガイギー　アクチエンゲゼルシヤフト ステロイド系カルボン酸エステル及びこれを含有する医薬
JPS61236794A (ja) * 1985-04-04 1986-10-22 アクチエボラゲツト・ドラコ 新規１６，１７−アセタ−ル置換アンドロスタン−１７β−カルボン酸エステル
JPS61286399A (ja) * 1985-04-04 1986-12-16 アクチエボラゲツト・ドラコ 新規なアンドロスタン−１７β−カルボン酸エステル
JP2003510276A (ja) * 1999-09-30 2003-03-18 フィアトリス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト ロテプレドノールとβ２アドレナリン受容体アゴニストの新規組み合わせ
JP2007520437A (ja) * 2003-06-19 2007-07-26 ボーダー、ニコラス・エス 局所又は他の局部投与用のソフト抗炎症性ステロイドの活性及び／又は作用持続性の増強
JP2009515844A (ja) * 2005-11-15 2009-04-16 グラクソ グループ リミテッド １７アルファ−カルボネート置換基を有する１７ベータ−フルオロメトキシカルボニル−アンドロスタ−４−エン−３−オン化合物
JP2009524649A (ja) * 2006-01-27 2009-07-02 スン プハルマ アドバンセド リサーチ カンパニー リミテド 新規１１β−ヒドロキシアンドロスタ−４−エン−３−オン
JP2009538313A (ja) * 2006-05-25 2009-11-05 ボーダー、ニコラス・エス 輸送体増強コルチコステロイド活性

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
HK1056181A1 (zh) 2000-08-05 2004-02-06 Glaxo Group Limited 作為抗炎劑的17β-硫代羧酸酯17α-芳基羰氧基氧雄甾烷衍生物
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
JP4446661B2 (ja) * 2001-04-30 2010-04-07 グラクソ グループ リミテッド 抗炎症性の、１７α位に環状エステル基を有するアンドロスタンの１７β−カルボチオ酸エステル誘導体
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
JP2020523357A (ja) 2017-06-13 2020-08-06 ボドール ラボラトリーズ， インコーポレイテッド 強力な抗炎症ソフトコルチコステロイド化合物およびその使用

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058999A (ja) * 1983-08-18 1985-04-05 チバ‐ガイギー　アクチエンゲゼルシヤフト ステロイド系カルボン酸エステル及びこれを含有する医薬
JPS61236794A (ja) * 1985-04-04 1986-10-22 アクチエボラゲツト・ドラコ 新規１６，１７−アセタ−ル置換アンドロスタン−１７β−カルボン酸エステル
JPS61286399A (ja) * 1985-04-04 1986-12-16 アクチエボラゲツト・ドラコ 新規なアンドロスタン−１７β−カルボン酸エステル
JP2003510276A (ja) * 1999-09-30 2003-03-18 フィアトリス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト ロテプレドノールとβ２アドレナリン受容体アゴニストの新規組み合わせ
JP2007520437A (ja) * 2003-06-19 2007-07-26 ボーダー、ニコラス・エス 局所又は他の局部投与用のソフト抗炎症性ステロイドの活性及び／又は作用持続性の増強
JP4893305B2 (ja) * 2003-06-19 2012-03-07 ボーダー、ニコラス・エス 局所又は他の局部投与用のソフト抗炎症性ステロイドの活性及び／又は作用持続性の増強
JP2009515844A (ja) * 2005-11-15 2009-04-16 グラクソ グループ リミテッド １７アルファ−カルボネート置換基を有する１７ベータ−フルオロメトキシカルボニル−アンドロスタ−４−エン−３−オン化合物
JP2009524649A (ja) * 2006-01-27 2009-07-02 スン プハルマ アドバンセド リサーチ カンパニー リミテド 新規１１β−ヒドロキシアンドロスタ−４−エン−３−オン
JP2009538313A (ja) * 2006-05-25 2009-11-05 ボーダー、ニコラス・エス 輸送体増強コルチコステロイド活性

Also Published As

Publication number Publication date
BE889563A (fr) 1981-11-03
SU1318169A3 (ru) 1987-06-15
JPS6411037B2 (enrdf_load_stackoverflow) 1989-02-23
ZA814440B (en) 1982-10-27

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