JPS57212161A - Isocarbostyril derivative - Google Patents

Isocarbostyril derivative

Info

Publication number
JPS57212161A
JPS57212161A JP56097430A JP9743081A JPS57212161A JP S57212161 A JPS57212161 A JP S57212161A JP 56097430 A JP56097430 A JP 56097430A JP 9743081 A JP9743081 A JP 9743081A JP S57212161 A JPS57212161 A JP S57212161A
Authority
JP
Japan
Prior art keywords
compound
formula
formulai
halogen
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56097430A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6355512B2 (en, 2012
Inventor
Hiroyasu Koyama
Masahiro Tsuji
Yoshikuni Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Priority to JP56097430A priority Critical patent/JPS57212161A/ja
Priority to US06/390,977 priority patent/US4517365A/en
Priority to GB08218195A priority patent/GB2101990B/en
Priority to DE19823223877 priority patent/DE3223877A1/de
Publication of JPS57212161A publication Critical patent/JPS57212161A/ja
Publication of JPS6355512B2 publication Critical patent/JPS6355512B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
JP56097430A 1981-06-25 1981-06-25 Isocarbostyril derivative Granted JPS57212161A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP56097430A JPS57212161A (en) 1981-06-25 1981-06-25 Isocarbostyril derivative
US06/390,977 US4517365A (en) 1981-06-25 1982-06-22 Isocarbostyril derivative
GB08218195A GB2101990B (en) 1981-06-25 1982-06-23 Isocarbostyril derivatives
DE19823223877 DE3223877A1 (de) 1981-06-25 1982-06-25 Isocarbostyrilderivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56097430A JPS57212161A (en) 1981-06-25 1981-06-25 Isocarbostyril derivative

Publications (2)

Publication Number Publication Date
JPS57212161A true JPS57212161A (en) 1982-12-27
JPS6355512B2 JPS6355512B2 (en, 2012) 1988-11-02

Family

ID=14192175

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56097430A Granted JPS57212161A (en) 1981-06-25 1981-06-25 Isocarbostyril derivative

Country Status (4)

Country Link
US (1) US4517365A (en, 2012)
JP (1) JPS57212161A (en, 2012)
DE (1) DE3223877A1 (en, 2012)
GB (1) GB2101990B (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02255618A (ja) * 1989-03-28 1990-10-16 Nisshin Flour Milling Co Ltd 緑内障治療剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116269A (ja) * 1982-12-24 1984-07-05 Nisshin Flour Milling Co Ltd イソカルボスチリル誘導体
JPS6019715A (ja) * 1983-07-12 1985-01-31 Nisshin Flour Milling Co Ltd 安定なイソカルボスチリル製剤
US5252583A (en) * 1989-03-28 1993-10-12 Nisshin Flour Milling Co., Ltd. Isoquinoline derivatives for the treatment of glaucoma or ocular hypertension
DK0389995T3 (da) * 1989-03-28 1995-07-03 Nisshin Flour Milling Co Isoquinolinderivater til behandling af glaukom eller okular hypertension
JP3141051B2 (ja) * 1992-10-09 2001-03-05 日清製粉株式会社 抗動脈硬化剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039874A (en) * 1963-08-23 1966-08-24 Bellon Labor Sa Roger New isoquinoline derivatives
US4129565A (en) * 1975-07-11 1978-12-12 Nisshin Flour Milling Co., Ltd. Isocarbostyril derivatives
GB1501149A (en) * 1975-07-11 1978-02-15 Nisshin Flour Milling Co Isocarbostyril derivatives
JPS57163367A (en) * 1981-04-01 1982-10-07 Nisshin Flour Milling Co Ltd Isocarbostyryl derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02255618A (ja) * 1989-03-28 1990-10-16 Nisshin Flour Milling Co Ltd 緑内障治療剤

Also Published As

Publication number Publication date
US4517365A (en) 1985-05-14
DE3223877C2 (en, 2012) 1990-08-30
DE3223877A1 (de) 1983-01-13
GB2101990A (en) 1983-01-26
JPS6355512B2 (en, 2012) 1988-11-02
GB2101990B (en) 1985-03-06

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