JPS57208990A - Cloning of cattle growing hormone gene in lower grade eucaryotic organism - Google Patents

Cloning of cattle growing hormone gene in lower grade eucaryotic organism

Info

Publication number
JPS57208990A
JPS57208990A JP57096374A JP9637482A JPS57208990A JP S57208990 A JPS57208990 A JP S57208990A JP 57096374 A JP57096374 A JP 57096374A JP 9637482 A JP9637482 A JP 9637482A JP S57208990 A JPS57208990 A JP S57208990A
Authority
JP
Japan
Prior art keywords
cloning
lower grade
hormone gene
eucaryotic organism
cattle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57096374A
Other languages
English (en)
Inventor
Hantaa Fureezaa Toomasu
Jiin Buruusu Baabara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of JPS57208990A publication Critical patent/JPS57208990A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/94Saccharomyces
    • Y10S435/942Saccharomyces cerevisiae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP57096374A 1981-06-08 1982-06-07 Cloning of cattle growing hormone gene in lower grade eucaryotic organism Pending JPS57208990A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/271,449 US4443539A (en) 1980-02-05 1981-06-08 Process for preparing bovine growth hormone

Publications (1)

Publication Number Publication Date
JPS57208990A true JPS57208990A (en) 1982-12-22

Family

ID=23035624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57096374A Pending JPS57208990A (en) 1981-06-08 1982-06-07 Cloning of cattle growing hormone gene in lower grade eucaryotic organism

Country Status (4)

Country Link
US (1) US4443539A (ja)
EP (1) EP0068646B1 (ja)
JP (1) JPS57208990A (ja)
DE (1) DE3266340D1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58174396A (ja) * 1982-03-08 1983-10-13 ジエネンテツク・インコ−ポレ−テツド 酵母菌による異種構造のタンパク質の発現、プロセシングおよび分泌

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0278121B1 (en) * 1981-09-18 1995-09-06 Genentech, Inc. Microbially produced bovine growth hormone (BGH) and its use
US4880910A (en) * 1981-09-18 1989-11-14 Genentech, Inc. Terminal methionyl bovine growth hormone and its use
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
EP0085036A1 (en) * 1982-01-18 1983-08-03 Monsanto Company Method for improved bovine milk production
EP0091539B2 (en) * 1982-03-31 1996-11-27 Ajinomoto Co., Inc. Gene coding for interleukin-2 polypeptide, recombinant DNA carrying said gene, cell lines possessing the recombinant DNA,and method for producing interleukin-2 using said cells
CA1224432A (en) * 1982-08-17 1987-07-21 Gary N. Buell Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
EP0111814A3 (en) * 1982-12-16 1985-08-14 Mgi Pharma, Inc. The cloning and expression of nucleotide sequences encoding bovine growth hormone
US4661454A (en) * 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
US5139936A (en) * 1983-02-28 1992-08-18 Collaborative Research, Inc. Use of the GAL1 yeast promoter
JPS60501140A (ja) * 1983-04-22 1985-07-25 アムジエン 酵母による外因性ポリペプチドの分泌
DE3486491T2 (de) 1983-04-25 2003-01-16 Chiron Corp Hybrid-DNS-Synthesis von reifen insulinähnlichen Wachstumsfaktoren
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty
US5252476A (en) * 1983-10-03 1993-10-12 Chiron Corporation Superoxide dismutase cloning and expression in microorganisms
US5710033A (en) * 1983-10-03 1998-01-20 Chiron Corporation Superoxide dismutase cloning and expression in microorganisms
US5629189A (en) 1983-10-03 1997-05-13 Chiron Corporation DNA encoding human cytoplasmic Cu/Zn superoxide dismutase
US4521409A (en) * 1983-10-03 1985-06-04 Cornell Research Foundation, Inc. Use of growth hormone to enhance ruminant mammary development
US5691139A (en) * 1983-10-03 1997-11-25 Chiron Corporation Genetic modification of superoxide dismutase to increase expression in microorganisms
PH23920A (en) * 1983-12-20 1990-01-23 Cetus Corp Glucoamylase cdna
US4935370A (en) * 1983-12-23 1990-06-19 Pfizer Inc. Expression plasmids for improved production of heterologous protein in bacteria
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
US5037806A (en) * 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins
US4861868A (en) * 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes
EP0229110B1 (en) 1985-06-26 1992-05-20 The Upjohn Company Solubilization and oxidation of somatotropin from transformed microorganisms
US4786501A (en) * 1985-07-15 1988-11-22 International Minerals & Chemical Corp. Cylindrical implants for the controlled release of growth hormones
JPS62224297A (ja) * 1986-03-25 1987-10-02 Kyowa Hakko Kogyo Co Ltd 魚類の成長ホルモンポリペプチドの製造法
US5270180A (en) * 1986-12-31 1993-12-14 Lucky, Ltd. Method for the production of salmon growth hormone using a synthetic gene
US5366876A (en) * 1986-12-31 1994-11-22 Lucky Ltd. Method for production of bovine growth hormone using a synthetic gene
US5541086A (en) * 1986-12-31 1996-07-30 Lucky, Ltd. Method for the production of porcine growth hormone using a synthetic gene in yeast cells
WO1988005078A1 (en) * 1986-12-31 1988-07-14 Lucky, Ltd. Method for the production of bovine growth hormone using a synthetic gene
DE68929273T2 (de) * 1988-08-24 2001-07-05 American Cyanamid Co Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung
WO1990002762A1 (en) 1988-09-02 1990-03-22 The Rockefeller University Macrophage-derived inflammatory mediator (mip-2)
US6787336B1 (en) 1989-10-12 2004-09-07 Ohio University/Edison Biotechnology Institute DNA encoding growth hormone antagonists
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US6583115B1 (en) 1989-10-12 2003-06-24 Ohio University/Edison Biotechnology Institute Methods for treating acromegaly and giantism with growth hormone antagonists
US5266477A (en) * 1990-02-02 1993-11-30 Pitman-Moore, Inc. Monoclonal antibodies which differentiate between native and modified porcine somatotropins
US5849694A (en) * 1990-07-16 1998-12-15 Synenki; Richard M. Stable and bioactive modified porcine somatotropin and pharmaceutical compositions thereof
EP0752853B1 (en) 1993-03-10 2005-09-21 Smithkline Beecham Corporation Human brain phosphodiesterase
ZA9711733B (en) 1996-12-31 1998-07-01 Monsanto Co Method for solubilization and naturation of somatotropins

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
DK173092B1 (da) * 1977-11-08 2000-01-10 Genentech Inc Rekombinant plasmid, fremgangsmåde til fremstilling af plasmidet, bakterie indeholdende plasmidet, samt fremgangsmåde til f
FI792481A (fi) * 1978-08-11 1980-02-12 Univ California Syntes av enkaroytiskt protein genom anvaendning av mikro-organismer
GB2033905B (en) * 1978-08-21 1982-10-13 Upjohn Co Bacterial preparation of proteins
FR2441659A1 (fr) * 1978-11-14 1980-06-13 Anvar Nouveaux plasmides hybrides et microorganismes les contenant
GB2068969B (en) * 1980-02-05 1983-07-27 Upjohn Co Gene expression
US4340674A (en) * 1980-05-05 1982-07-20 The Upjohn Company Cointegrate plasmids and their construction from plasmids of Escherichia and Streptomyces
IL59690A (en) * 1980-03-24 1983-11-30 Yeda Res & Dev Production of bovine growth hormone by microorganisms and modified microorganisms adapted to produce it
US4332898A (en) * 1980-05-22 1982-06-01 The Upjohn Company Hybrid plasmid and process of making same
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
EP0058002A3 (en) * 1981-01-26 1983-06-29 The Upjohn Company Process for stabilising potential plasmid vectors and novel plasmids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58174396A (ja) * 1982-03-08 1983-10-13 ジエネンテツク・インコ−ポレ−テツド 酵母菌による異種構造のタンパク質の発現、プロセシングおよび分泌

Also Published As

Publication number Publication date
EP0068646A1 (en) 1983-01-05
DE3266340D1 (en) 1985-10-24
EP0068646B1 (en) 1985-09-18
US4443539A (en) 1984-04-17

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