JPS57188514A - Fluorine compound emulsion - Google Patents
Fluorine compound emulsionInfo
- Publication number
- JPS57188514A JPS57188514A JP7206081A JP7206081A JPS57188514A JP S57188514 A JPS57188514 A JP S57188514A JP 7206081 A JP7206081 A JP 7206081A JP 7206081 A JP7206081 A JP 7206081A JP S57188514 A JPS57188514 A JP S57188514A
- Authority
- JP
- Japan
- Prior art keywords
- fluorine compound
- substitute
- compound emulsion
- aqueous solution
- blood cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE:A fluorine compound emulsion that is made by emulsifying a specific fluoro-olefin compound of 10 carbon atoms as the major component in a physiologically permissible aqueous solution, thus being used as an oxygen-conceying carrier, blood cell substitute or perfusat for storing internal organs. CONSTITUTION:Mainly, a compound of formulaI(R1-R3 are F, CF3, CF2CF3, or CF2CF2CF3, formula II where R1-R3 are not F simultaneously and their carbon number totals 10) is emulsified in a physiologically permissible aqueous solution by 10-50, preferably 10-40w/v%, preferably in the presence of an emulsifier such as polyoxyethylene-polyoxypropylene copolymer of 6,000-17,000 molecular weight by 1-5w/v% to prepare the objective fluorine compound emulsion with high adaptability as a substitute of conventional fluorine compound used for medical purposes or blood cell substitute.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7206081A JPS57188514A (en) | 1981-05-12 | 1981-05-12 | Fluorine compound emulsion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7206081A JPS57188514A (en) | 1981-05-12 | 1981-05-12 | Fluorine compound emulsion |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57188514A true JPS57188514A (en) | 1982-11-19 |
Family
ID=13478462
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7206081A Pending JPS57188514A (en) | 1981-05-12 | 1981-05-12 | Fluorine compound emulsion |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57188514A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6183121A (en) * | 1984-10-01 | 1986-04-26 | Green Cross Corp:The | Remedy for ischemic ulcer |
JPH0798745B2 (en) * | 1988-04-29 | 1995-10-25 | ヘマゲン/ピーエフシー | Improved emulsions of highly fluorinated organic compounds |
-
1981
- 1981-05-12 JP JP7206081A patent/JPS57188514A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6183121A (en) * | 1984-10-01 | 1986-04-26 | Green Cross Corp:The | Remedy for ischemic ulcer |
JPH0798745B2 (en) * | 1988-04-29 | 1995-10-25 | ヘマゲン/ピーエフシー | Improved emulsions of highly fluorinated organic compounds |
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