JPS57183780A - Beta-d-xylopyranoside compound - Google Patents

Beta-d-xylopyranoside compound

Info

Publication number
JPS57183780A
JPS57183780A JP6522681A JP6522681A JPS57183780A JP S57183780 A JPS57183780 A JP S57183780A JP 6522681 A JP6522681 A JP 6522681A JP 6522681 A JP6522681 A JP 6522681A JP S57183780 A JPS57183780 A JP S57183780A
Authority
JP
Japan
Prior art keywords
compound
formula
activity
treating
xylopyranoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6522681A
Other languages
Japanese (ja)
Other versions
JPS6361308B2 (en
Inventor
Ryoji Noyori
Akira Suzuki
Minoru Okayama
Katsukiyo Sakurai
Shigeki Kanbara
Yoshio Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Priority to JP6522681A priority Critical patent/JPS57183780A/en
Priority to EP84100499A priority patent/EP0118676B1/en
Priority to EP84100498A priority patent/EP0117413B1/en
Priority to DE8484100498T priority patent/DE3176380D1/en
Priority to DE8484100499T priority patent/DE3176465D1/en
Priority to DE8181110216T priority patent/DE3172379D1/en
Priority to EP81110216A priority patent/EP0053827B1/en
Publication of JPS57183780A publication Critical patent/JPS57183780A/en
Priority to US06/472,786 priority patent/US4454123A/en
Publication of JPS6361308B2 publication Critical patent/JPS6361308B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:The compound of formulaI(X is O, S, or methylene; Y is H, Li, Na, K, Mg, Ca, or Al; n is 1W3).
EXAMPLE: p-Carboxyphenyl β-D-xylopyranoside.
USE: Drug having carcinostatic activity, arteriosclerosis-suppressing activity, antithrombotic activity, etc. It has low toxicity and can be administered for a long period. The compound does not cause the problems such as teratogenesis, allergic reactions, etc., and has high safety.
PROCESS: The compound of formulaIwherein X is O, Y is H and n is 1 can be prepared by (1) acetylating D-xylose of formula II to the tetraacetate of formula III, (2) treating the product with AlBr3, (3) reacting the resultant compound of formula IV with methyl p-hydroxybenzoate in the presence of silver oxide to obtain the compound of formula V, and (4) treating the β-isomer of the compound of formula V with a catalytic amount of a base such as LiOH in methanol.
COPYRIGHT: (C)1982,JPO&Japio
JP6522681A 1980-12-09 1981-05-01 Beta-d-xylopyranoside compound Granted JPS57183780A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP6522681A JPS57183780A (en) 1981-05-01 1981-05-01 Beta-d-xylopyranoside compound
EP84100499A EP0118676B1 (en) 1980-12-09 1981-12-07 D-xylopyranoside series compounds and therapeutical compositions containing same
EP84100498A EP0117413B1 (en) 1980-12-09 1981-12-07 D-xylopyranoside series compounds and therapeutical compositions containing same
DE8484100498T DE3176380D1 (en) 1980-12-09 1981-12-07 D-xylopyranoside series compounds and therapeutical compositions containing same
DE8484100499T DE3176465D1 (en) 1980-12-09 1981-12-07 D-xylopyranoside series compounds and therapeutical compositions containing same
DE8181110216T DE3172379D1 (en) 1980-12-09 1981-12-07 D-xylopyranoside series compounds and therapeutical compositions containing same
EP81110216A EP0053827B1 (en) 1980-12-09 1981-12-07 D-xylopyranoside series compounds and therapeutical compositions containing same
US06/472,786 US4454123A (en) 1980-12-09 1983-03-07 O-xylopyranoside series compounds and methods of use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6522681A JPS57183780A (en) 1981-05-01 1981-05-01 Beta-d-xylopyranoside compound

Publications (2)

Publication Number Publication Date
JPS57183780A true JPS57183780A (en) 1982-11-12
JPS6361308B2 JPS6361308B2 (en) 1988-11-28

Family

ID=13280784

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6522681A Granted JPS57183780A (en) 1980-12-09 1981-05-01 Beta-d-xylopyranoside compound

Country Status (1)

Country Link
JP (1) JPS57183780A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62226974A (en) * 1986-03-28 1987-10-05 Mitsui Petrochem Ind Ltd Production of tetrahydropyran derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62226974A (en) * 1986-03-28 1987-10-05 Mitsui Petrochem Ind Ltd Production of tetrahydropyran derivative

Also Published As

Publication number Publication date
JPS6361308B2 (en) 1988-11-28

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