JPS57183766A - 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation - Google Patents

5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation

Info

Publication number
JPS57183766A
JPS57183766A JP6689181A JP6689181A JPS57183766A JP S57183766 A JPS57183766 A JP S57183766A JP 6689181 A JP6689181 A JP 6689181A JP 6689181 A JP6689181 A JP 6689181A JP S57183766 A JPS57183766 A JP S57183766A
Authority
JP
Japan
Prior art keywords
lower alkyl
carbamoylmethylthiazole
formulai
phenyl
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6689181A
Other languages
Japanese (ja)
Inventor
Tetsuzo Kato
Jiro Horiuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
KANTOU ISHI SEIYAKU KK
Original Assignee
KANTO ISHI PHARMA CO Ltd
KANTOU ISHI SEIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANTO ISHI PHARMA CO Ltd, KANTOU ISHI SEIYAKU KK filed Critical KANTO ISHI PHARMA CO Ltd
Priority to JP6689181A priority Critical patent/JPS57183766A/en
Publication of JPS57183766A publication Critical patent/JPS57183766A/en
Pending legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(R1 is H or lower alkyl; R2 is lower alkyl, amino wherein aryl or phenyl may be substituted, lower alkyl, phenyl, or pyridyl).
EXAMPLE: 2-Amino-4-(o-methoxycarbonylphenyl)carbamoylmethylthiazole.
USE: An antiphlogistic anodyne or antitumor agent.
PROCESS: An o-γ-bromine substituted acetacetamidobenzoic acid shown by the formula II is reacted with a thioamide shown by the formula III in an inert solvent such as methanol, ethanol, chloroform, etc. for tens minutes W several hours at room temperature with stirring or under reflux by heating, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP6689181A 1981-05-06 1981-05-06 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation Pending JPS57183766A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6689181A JPS57183766A (en) 1981-05-06 1981-05-06 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6689181A JPS57183766A (en) 1981-05-06 1981-05-06 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS57183766A true JPS57183766A (en) 1982-11-12

Family

ID=13328981

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6689181A Pending JPS57183766A (en) 1981-05-06 1981-05-06 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57183766A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1311160A1 (en) * 2000-07-28 2003-05-21 Korea Institute Of Science And Technology 2-phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1311160A1 (en) * 2000-07-28 2003-05-21 Korea Institute Of Science And Technology 2-phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same
EP1311160A4 (en) * 2000-07-28 2004-04-21 Korea Inst Sci & Tech 2-phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same
US6921770B2 (en) 2000-07-28 2005-07-26 Korea Institute Of Science And Technology 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same

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