JPS57183766A - 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation - Google Patents
5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparationInfo
- Publication number
- JPS57183766A JPS57183766A JP6689181A JP6689181A JPS57183766A JP S57183766 A JPS57183766 A JP S57183766A JP 6689181 A JP6689181 A JP 6689181A JP 6689181 A JP6689181 A JP 6689181A JP S57183766 A JPS57183766 A JP S57183766A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- carbamoylmethylthiazole
- formulai
- phenyl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(R1 is H or lower alkyl; R2 is lower alkyl, amino wherein aryl or phenyl may be substituted, lower alkyl, phenyl, or pyridyl).
EXAMPLE: 2-Amino-4-(o-methoxycarbonylphenyl)carbamoylmethylthiazole.
USE: An antiphlogistic anodyne or antitumor agent.
PROCESS: An o-γ-bromine substituted acetacetamidobenzoic acid shown by the formula II is reacted with a thioamide shown by the formula III in an inert solvent such as methanol, ethanol, chloroform, etc. for tens minutes W several hours at room temperature with stirring or under reflux by heating, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6689181A JPS57183766A (en) | 1981-05-06 | 1981-05-06 | 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6689181A JPS57183766A (en) | 1981-05-06 | 1981-05-06 | 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57183766A true JPS57183766A (en) | 1982-11-12 |
Family
ID=13328981
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6689181A Pending JPS57183766A (en) | 1981-05-06 | 1981-05-06 | 5-(o-carboxyphenyl)carbamoylmethylthiazole derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57183766A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1311160A1 (en) * | 2000-07-28 | 2003-05-21 | Korea Institute Of Science And Technology | 2-phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same |
-
1981
- 1981-05-06 JP JP6689181A patent/JPS57183766A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1311160A1 (en) * | 2000-07-28 | 2003-05-21 | Korea Institute Of Science And Technology | 2-phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same |
EP1311160A4 (en) * | 2000-07-28 | 2004-04-21 | Korea Inst Sci & Tech | 2-phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same |
US6921770B2 (en) | 2000-07-28 | 2005-07-26 | Korea Institute Of Science And Technology | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same |
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