JPS5716859A - Preparation of n,n'-di-substituted thiourea - Google Patents
Preparation of n,n'-di-substituted thioureaInfo
- Publication number
- JPS5716859A JPS5716859A JP9066780A JP9066780A JPS5716859A JP S5716859 A JPS5716859 A JP S5716859A JP 9066780 A JP9066780 A JP 9066780A JP 9066780 A JP9066780 A JP 9066780A JP S5716859 A JPS5716859 A JP S5716859A
- Authority
- JP
- Japan
- Prior art keywords
- reaction
- cyanamide
- titled compound
- carried out
- carbon disulfide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To prepare the titled compound useful as rubber vulcanization accelerator, pharmaceuticals, etc., without using difficult operations, in high yield, by reacting carbon disulfide and a primary amine with cyanamide as reaction components.
CONSTITUTION: Carbon disulfide is reacted with a primary amine, and the reaction product is further reacted with cyanamide to obtain the titled compound of formula I (R is alkyl, etc.). The latter reaction may be carried out by heating up to the boiling point of the amine, and the reaction goes to completion in several hours at the reaction temperature of 40W60°C.
EFFECT: The raw materials are available at low cost. Since there is no by-production of hydrogen sulfide and the reaction can be carried out in an aqueous solvent, the separation of the produced N,N'-di-substituted thiourea is generally easy, and the process is extremely advantageous from the industrial viewpoint.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9066780A JPS5716859A (en) | 1980-07-04 | 1980-07-04 | Preparation of n,n'-di-substituted thiourea |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9066780A JPS5716859A (en) | 1980-07-04 | 1980-07-04 | Preparation of n,n'-di-substituted thiourea |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5716859A true JPS5716859A (en) | 1982-01-28 |
JPH0118894B2 JPH0118894B2 (en) | 1989-04-07 |
Family
ID=14004881
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9066780A Granted JPS5716859A (en) | 1980-07-04 | 1980-07-04 | Preparation of n,n'-di-substituted thiourea |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5716859A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102731357A (en) * | 2012-07-04 | 2012-10-17 | 山东汇海医药化工有限公司 | Preparation method of high purity N,N'-dicyclohexylthiourea |
-
1980
- 1980-07-04 JP JP9066780A patent/JPS5716859A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102731357A (en) * | 2012-07-04 | 2012-10-17 | 山东汇海医药化工有限公司 | Preparation method of high purity N,N'-dicyclohexylthiourea |
Also Published As
Publication number | Publication date |
---|---|
JPH0118894B2 (en) | 1989-04-07 |
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