JPS57165336A - Preparation of ketones - Google Patents

Preparation of ketones

Info

Publication number
JPS57165336A
JPS57165336A JP56050420A JP5042081A JPS57165336A JP S57165336 A JPS57165336 A JP S57165336A JP 56050420 A JP56050420 A JP 56050420A JP 5042081 A JP5042081 A JP 5042081A JP S57165336 A JPS57165336 A JP S57165336A
Authority
JP
Japan
Prior art keywords
ketone
reducing agent
reaction
formula
carried out
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56050420A
Other languages
Japanese (ja)
Other versions
JPH0154336B2 (en
Inventor
Mitsuaki Mukoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP56050420A priority Critical patent/JPS57165336A/en
Publication of JPS57165336A publication Critical patent/JPS57165336A/en
Publication of JPH0154336B2 publication Critical patent/JPH0154336B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain especially an unsymmetrical ketone preferably without forming by-products practically, by reacting a pyridylcarboxylate or a pyridylthioate with an organic iodide in the presence of both a nickel halide and a metal reducing agent.
CONSTITUTION: A compound shown by the formulaI(X is H or substituent group; Y is O, S; R1 is hydrocarbon residue which may be substituted by a functional group such as ether, thioether, ester, ketone, halogen, etc.) is reacted with a compound shown by the formula R2I in the presence of a catalytic amount of a nickel halide (e.g., nickelous chloride) and ≥ a stoichiometric amount of metal reducing agent (e.g., zinc), to give a ketone shown by the formula II. The reaction is carried out in an solvent such as DMF, etc. at room temperatureW100°C for tens minutesW about 20hr.
EFFECT: A raw material having an active group can be used without protecting it, the preparation of an organic metal is not required, and the reaction is carried out under mild conditions by one pot method.
COPYRIGHT: (C)1982,JPO&Japio
JP56050420A 1981-04-03 1981-04-03 Preparation of ketones Granted JPS57165336A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56050420A JPS57165336A (en) 1981-04-03 1981-04-03 Preparation of ketones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56050420A JPS57165336A (en) 1981-04-03 1981-04-03 Preparation of ketones

Publications (2)

Publication Number Publication Date
JPS57165336A true JPS57165336A (en) 1982-10-12
JPH0154336B2 JPH0154336B2 (en) 1989-11-17

Family

ID=12858367

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56050420A Granted JPS57165336A (en) 1981-04-03 1981-04-03 Preparation of ketones

Country Status (1)

Country Link
JP (1) JPS57165336A (en)

Also Published As

Publication number Publication date
JPH0154336B2 (en) 1989-11-17

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