JPS57165324A - Cultivation of rabies virus - Google Patents
Cultivation of rabies virusInfo
- Publication number
- JPS57165324A JPS57165324A JP4975081A JP4975081A JPS57165324A JP S57165324 A JPS57165324 A JP S57165324A JP 4975081 A JP4975081 A JP 4975081A JP 4975081 A JP4975081 A JP 4975081A JP S57165324 A JPS57165324 A JP S57165324A
- Authority
- JP
- Japan
- Prior art keywords
- culture
- virus
- cell
- cell strain
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: To obtain inexpensively a large amount of the titled virus liquid having high virus value free from side effects, by cultivating a novel flotation culture cell having succeeded from the hepatic or pulmonary passage cell strain of young hamster using a medium having no serum by spinner culture.
CONSTITUTION: The hepatic passage cell strain of young hamster and the pulmonoary passage cell strain of young hamster are cultivated by single layer culture. After the cell is sufficiently propagated, it is transferred to a spinner culture container for flotation culture, and a trypsine solution is added to the cell to carry out spinner culture. These operations are repeated and the cell is acclimated to give a novel flotation culture cell having succeeded from the hepatic passage cell strain and the pulmonary passage cell strain of young hamster. This is cultivated in a medium containing no bovine serum by spinner culture, to give the desired virus solution. The virus solution has higher virus value than a culture solution of rabies virus using caprine brain, and a vaccine for preventing rabies can be prepared safely at low cost since it has no side effects.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4975081A JPS57165324A (en) | 1981-04-02 | 1981-04-02 | Cultivation of rabies virus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4975081A JPS57165324A (en) | 1981-04-02 | 1981-04-02 | Cultivation of rabies virus |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57165324A true JPS57165324A (en) | 1982-10-12 |
JPS6225351B2 JPS6225351B2 (en) | 1987-06-02 |
Family
ID=12839851
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4975081A Granted JPS57165324A (en) | 1981-04-02 | 1981-04-02 | Cultivation of rabies virus |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57165324A (en) |
-
1981
- 1981-04-02 JP JP4975081A patent/JPS57165324A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6225351B2 (en) | 1987-06-02 |
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