JPS57160060A - Pulsating flow preventing device for high speed liquid chromatography - Google Patents

Pulsating flow preventing device for high speed liquid chromatography

Info

Publication number
JPS57160060A
JPS57160060A JP4605681A JP4605681A JPS57160060A JP S57160060 A JPS57160060 A JP S57160060A JP 4605681 A JP4605681 A JP 4605681A JP 4605681 A JP4605681 A JP 4605681A JP S57160060 A JPS57160060 A JP S57160060A
Authority
JP
Japan
Prior art keywords
liquid
flow
pump
diaphragm
liquid chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4605681A
Other languages
Japanese (ja)
Inventor
Tatsuo Kurahashi
Hirohito Nishino
Minoru Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yanagimoto Seisakusho Co Ltd
Original Assignee
Yanagimoto Seisakusho Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yanagimoto Seisakusho Co Ltd filed Critical Yanagimoto Seisakusho Co Ltd
Priority to JP4605681A priority Critical patent/JPS57160060A/en
Publication of JPS57160060A publication Critical patent/JPS57160060A/en
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/322—Control of physical parameters of the fluid carrier of pressure or speed pulse dampers

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Pipe Accessories (AREA)
  • Reciprocating Pumps (AREA)

Abstract

PURPOSE:To make smooth the pulsating flow in a coveyed liquid flow channel and stabilize detection performance by installing a flat shaped damper flow route chamber in the conveyed liquid flow channel from a pump of small piston type to a liquid chromatography column and forming a partition in a compressed liquid chamber with a diaphragm. CONSTITUTION:In a pulsating flow prevention device 1 that is provided in the liquid coveying route to the column of a liquid chromatography from a pump of small piston type, a diaphragm made of teflon or other material is provided between a metallic cover block 3 that has a liquid inlet, liquid outlet and a recess 7 and a vessel block 3. The diaphragm 4 separates with air-tightness a compression room 11 that receives hexane or other liquid that has compressibility as large as several times the water and a bottom plug and a damper flow route chamber. With this arrangement pulsation flow from the pump is smoothed and instability in detection performance and causes of noise are removed. The device 1 is of small size and simple construction with about 80mm. in diameter and about 1mm. in depth and about 700ml capacity.
JP4605681A 1981-03-28 1981-03-28 Pulsating flow preventing device for high speed liquid chromatography Pending JPS57160060A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4605681A JPS57160060A (en) 1981-03-28 1981-03-28 Pulsating flow preventing device for high speed liquid chromatography

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4605681A JPS57160060A (en) 1981-03-28 1981-03-28 Pulsating flow preventing device for high speed liquid chromatography

Publications (1)

Publication Number Publication Date
JPS57160060A true JPS57160060A (en) 1982-10-02

Family

ID=12736356

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4605681A Pending JPS57160060A (en) 1981-03-28 1981-03-28 Pulsating flow preventing device for high speed liquid chromatography

Country Status (1)

Country Link
JP (1) JPS57160060A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62179401U (en) * 1986-05-07 1987-11-14
US4794954A (en) * 1985-05-13 1989-01-03 Showa Denko Kabushiki Kaisha Apparatus and method for prevention of pulsating flow in liquid chromatograph
JPS6435293U (en) * 1987-08-27 1989-03-03
WO2002029106A3 (en) * 2000-10-03 2002-07-11 California Inst Of Techn Microfluidic devices and methods of use
JP2020088384A (en) * 2018-11-15 2020-06-04 キヤノン株式会社 Pulsation damper with gas retention

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54157336A (en) * 1978-06-02 1979-12-12 Varian Associates Pulse damper

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54157336A (en) * 1978-06-02 1979-12-12 Varian Associates Pulse damper

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794954A (en) * 1985-05-13 1989-01-03 Showa Denko Kabushiki Kaisha Apparatus and method for prevention of pulsating flow in liquid chromatograph
JPS62179401U (en) * 1986-05-07 1987-11-14
JPS6435293U (en) * 1987-08-27 1989-03-03
WO2002029106A3 (en) * 2000-10-03 2002-07-11 California Inst Of Techn Microfluidic devices and methods of use
US7258774B2 (en) 2000-10-03 2007-08-21 California Institute Of Technology Microfluidic devices and methods of use
US8992858B2 (en) 2000-10-03 2015-03-31 The United States of America National Institute of Health (NIH), U.S. Dept. of Health and Human Services (DHHS) Microfluidic devices and methods of use
JP2020088384A (en) * 2018-11-15 2020-06-04 キヤノン株式会社 Pulsation damper with gas retention

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