JPS57146762A - Phenylpiperazine derivatives of hetarylphenol and hetarylaniline, manufacture and medicine - Google Patents
Phenylpiperazine derivatives of hetarylphenol and hetarylaniline, manufacture and medicineInfo
- Publication number
- JPS57146762A JPS57146762A JP57003531A JP353182A JPS57146762A JP S57146762 A JPS57146762 A JP S57146762A JP 57003531 A JP57003531 A JP 57003531A JP 353182 A JP353182 A JP 353182A JP S57146762 A JPS57146762 A JP S57146762A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- carbon atoms
- hetarylphenol
- hetarylaniline
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical class C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000001781 1,3,4-oxadiazolyl group Chemical group 0.000 abstract 1
- JMCIDTWYFZBDNL-UHFFFAOYSA-N 1-(1-phenylpropyl)piperazine Chemical compound C=1C=CC=CC=1C(CC)N1CCNCC1 JMCIDTWYFZBDNL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 125000001425 triazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813101502 DE3101502A1 (de) | 1981-01-19 | 1981-01-19 | Phenylpiperazinderivate von hetarylphenolen und hetarylanilinen, ihre hersttellung und diese enthaltendetherapeutische mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57146762A true JPS57146762A (en) | 1982-09-10 |
Family
ID=6122877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57003531A Pending JPS57146762A (en) | 1981-01-19 | 1982-01-14 | Phenylpiperazine derivatives of hetarylphenol and hetarylaniline, manufacture and medicine |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4619929A (ja) |
| EP (1) | EP0056866B1 (ja) |
| JP (1) | JPS57146762A (ja) |
| AT (1) | ATE13885T1 (ja) |
| CA (1) | CA1187878A (ja) |
| DE (2) | DE3101502A1 (ja) |
| DK (1) | DK19182A (ja) |
| GR (1) | GR77632B (ja) |
| IE (1) | IE52035B1 (ja) |
| ZA (1) | ZA82293B (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008543792A (ja) * | 2005-06-17 | 2008-12-04 | アンドルシェルシュ・インコーポレイテッド | ヘリックス１２指向非ステロイド性抗アンドロゲン |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3609597A1 (de) * | 1986-03-21 | 1987-10-01 | Hoechst Ag | 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
| US4851526A (en) * | 1987-09-04 | 1989-07-25 | Schering A.G. | 1-(4-Substituted phenyl)-1H-imidazoles compounds |
| US4891375A (en) * | 1988-01-13 | 1990-01-02 | Pfizer Inc. | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds |
| FR2672052B1 (fr) * | 1991-01-28 | 1995-05-24 | Esteve Labor Dr | Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments. |
| US5486517A (en) * | 1994-05-10 | 1996-01-23 | Warner-Lambert Company | Benzimidazoles and imidazopyridines as central nervous system agents |
| US5414010A (en) * | 1994-05-10 | 1995-05-09 | Warner-Lambert Company | Dimeric benzimidazoles as central nervous system agents |
| CN107511174B (zh) * | 2016-06-18 | 2020-10-30 | 中国石油化工股份有限公司 | 无粘结剂mww结构分子筛催化剂的制备方法 |
| CN107511171B (zh) * | 2016-06-18 | 2020-10-30 | 中国石油化工股份有限公司 | 无粘结剂Beta分子筛催化剂的制备方法 |
| CN107511165B (zh) * | 2016-06-18 | 2020-10-30 | 中国石油化工股份有限公司 | 无粘结剂丝光分子筛催化剂的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MC641A1 (fr) * | 1967-03-08 | 1967-12-05 | Mauvernay Roland Yves | Nouveaux composés chimiques et procédé pour leur préparation |
| AT317209B (de) * | 1971-06-07 | 1974-08-26 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer Phenylimidazolidinonderivate und ihrer Salze |
| AT317203B (de) * | 1971-06-07 | 1974-08-26 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer Phenylimidazolidinonderivate und ihrer Salze |
| US3937708A (en) * | 1971-06-07 | 1976-02-10 | Boehringer Ingelheim Gmbh | N-phenyl-imidazolidine-1-ones |
| DE2335432A1 (de) * | 1973-07-12 | 1975-01-30 | Boehringer Mannheim Gmbh | 3,4-dihydro-2h-naphthalinon-(1)5-oxy-propyl-piperazin-derivate und verfahren zu ihrer herstellung |
| DE2263211A1 (de) * | 1972-12-23 | 1974-07-04 | Boehringer Sohn Ingelheim | Neue arylpiperazine und verfahren zu ihrer herstellung |
| DE2824677A1 (de) * | 1978-06-06 | 1979-12-20 | Hoechst Ag | Neue substituierte phenylpiperazinderivate und verfahren zu deren herstellung |
| DE3005287A1 (de) * | 1980-02-13 | 1981-08-20 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
| DE3101456A1 (de) * | 1981-01-19 | 1982-09-02 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinyl-propanole von hetarylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
-
1981
- 1981-01-19 DE DE19813101502 patent/DE3101502A1/de not_active Withdrawn
- 1981-12-23 AT AT81110719T patent/ATE13885T1/de active
- 1981-12-23 GR GR66899A patent/GR77632B/el unknown
- 1981-12-23 EP EP81110719A patent/EP0056866B1/de not_active Expired
- 1981-12-23 DE DE8181110719T patent/DE3171074D1/de not_active Expired
-
1982
- 1982-01-14 JP JP57003531A patent/JPS57146762A/ja active Pending
- 1982-01-14 CA CA000394179A patent/CA1187878A/en not_active Expired
- 1982-01-15 IE IE79/82A patent/IE52035B1/en unknown
- 1982-01-18 DK DK19182A patent/DK19182A/da not_active Application Discontinuation
- 1982-01-18 ZA ZA82293A patent/ZA82293B/xx unknown
-
1984
- 1984-03-19 US US06/590,746 patent/US4619929A/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008543792A (ja) * | 2005-06-17 | 2008-12-04 | アンドルシェルシュ・インコーポレイテッド | ヘリックス１２指向非ステロイド性抗アンドロゲン |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE13885T1 (de) | 1985-07-15 |
| ZA82293B (en) | 1982-12-29 |
| US4619929A (en) | 1986-10-28 |
| EP0056866A2 (de) | 1982-08-04 |
| EP0056866A3 (en) | 1982-08-18 |
| DE3101502A1 (de) | 1982-08-26 |
| GR77632B (ja) | 1984-09-25 |
| IE52035B1 (en) | 1987-05-27 |
| DK19182A (da) | 1982-07-20 |
| DE3171074D1 (en) | 1985-07-25 |
| CA1187878A (en) | 1985-05-28 |
| IE820079L (en) | 1982-07-19 |
| EP0056866B1 (de) | 1985-06-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3262880D1 (en) | Tricyclic ethers, process for their preparation and their use in pharmaceutical preparations | |
| DE3061424D1 (en) | 8-phenyl purines, their preparation and medicaments containing them | |
| MTP915B (en) | Pyrralidine derivatives | |
| JPS57146762A (en) | Phenylpiperazine derivatives of hetarylphenol and hetarylaniline, manufacture and medicine | |
| ZA815043B (en) | Diazepine derivatives,process for their preparation,and pharmaceutical compositions thereof | |
| ZA82294B (en) | (hetarylphenoxy)-(phenylpiperazinyl)-propanols,their preparation and drugs containing these compounds | |
| IL61687A (en) | (benzothiazole-2-yl-thio)-phenylpropionic acid derivatives,pharmaceutical formulations containing them and a process for their preparation | |
| EP0194579A3 (en) | 3-pyridylmethylnaphthyl derivatives, process for their preparation and their use as medicaments | |
| GR3002944T3 (en) | Tetrahydro-beta-carbolines, process for their preparation and their use as medicaments | |
| DE3365933D1 (en) | Substituted thienobenzodiazepinones, process for their preparation and medicines containing these compounds | |
| IL59052A0 (en) | Hexahydro-1,4-oxazepine derivatives their preparation and pharmaceutical compositions containing them | |
| ES8604122A1 (es) | Procedimiento de preparacion de eteres oximas basicos y de sus sales de adicion acidas farmaceuticamente aceptables | |
| NO166179C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive aralkyl -4h-1,2,4-triazolderivater. | |
| ES8308315A1 (es) | "procedimiento para la preparacion de nuevos derivados de anilino-1,2,3-triazol". | |
| ZA838139B (en) | Semicarbazides,process for preparing these,and pharmaceutical compositions thereof |