JPS57136564A - Preparation of allene derivative - Google Patents
Preparation of allene derivativeInfo
- Publication number
- JPS57136564A JPS57136564A JP2091781A JP2091781A JPS57136564A JP S57136564 A JPS57136564 A JP S57136564A JP 2091781 A JP2091781 A JP 2091781A JP 2091781 A JP2091781 A JP 2091781A JP S57136564 A JPS57136564 A JP S57136564A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula iii
- metal
- alkyl
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To prepare the titled compound useful as a raw material of pharmaceuticals, etc., easily, safely and economically in an industrial scale, by reacting an α-thiocarbonyl compound with a propargyl compound in the presence of a metal carbonate or a metal bicarbonate.
CONSTITUTION: The allene derivative of formulaI(R1 is alkyl, etc.; R2 is H, alkyl, etc.; R3 is H, alkyl, etc.) is prepared by reacting an α-thiocarbonyl compound of formula II with a propargyl compound of formula III (X is halogen or sulfonate group) in the presence of a metal carbonate or a metal bicarbonate (e.g. an alkali metal or an alkaline earth metal salt such as Na2CO3, NaHCO3, etc.). Equivalent amount of the metal salt based on the compound of formula III is sufficient for the purpose; however, larger amount of the salt may be used. The amount of the compound of formula III is equimolar to the compound of formula III. When water is present in the reaction system, the yield can be improved by using ≥1mol, pref. ≥1.3 equivalent of the compound of formula III.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2091781A JPS57136564A (en) | 1981-02-17 | 1981-02-17 | Preparation of allene derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2091781A JPS57136564A (en) | 1981-02-17 | 1981-02-17 | Preparation of allene derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57136564A true JPS57136564A (en) | 1982-08-23 |
Family
ID=12040570
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2091781A Pending JPS57136564A (en) | 1981-02-17 | 1981-02-17 | Preparation of allene derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57136564A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006257006A (en) * | 2005-03-16 | 2006-09-28 | Tosoh F-Tech Inc | Method for producing allene having fluorine-containing alkyl group |
-
1981
- 1981-02-17 JP JP2091781A patent/JPS57136564A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006257006A (en) * | 2005-03-16 | 2006-09-28 | Tosoh F-Tech Inc | Method for producing allene having fluorine-containing alkyl group |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS54130560A (en) | Sipro compound and its preparation | |
DE3462498D1 (en) | Alkanoyloxybenzenesulfonate salt production | |
JPS5576829A (en) | Beta,gamma-dihydropolyprenyl alcohol and hypotensive agent made from it | |
JPS5798270A (en) | 1,2-disubstituted-4-chloroimidazole-5-acetic acid derivative | |
JPS57136564A (en) | Preparation of allene derivative | |
JPS5767555A (en) | Production of s-(aminoalkyl)thiosulfate salt | |
JPS5583791A (en) | 7-methoxycephalosporin derivative and its preparation | |
JPS5517324A (en) | Preparation of thiophosphoric acid ester | |
JPS5562053A (en) | Production of aminophenol ether | |
JPS54138586A (en) | Preparation of isocyanuric acid ester | |
JPS57144253A (en) | Preparation of crude aminoalkylthiol | |
JPS56113727A (en) | Preparation of arylacetaldehyde | |
JPS5540617A (en) | Mitomycin derivative | |
JPS5618971A (en) | Alpha-halogeno-beta-benzosulfimidopropionitrile and its preparation | |
JPS57136563A (en) | Preparation of 4-thio-3-buten-2-one derivative | |
JPS5463077A (en) | Preparation of imidazoline derivative | |
JPS57175197A (en) | Cysteine-glucuronolactone salt | |
JPS57193444A (en) | Sulfonate derivative, its preparation and antilipemic agent containing the same | |
JPS5592360A (en) | M-sulfonamido-benzamides | |
JPS5699448A (en) | Preparation of lower alkoxyaniline | |
JPS57212172A (en) | Preparation of cyanuric halide derivative | |
JPS5592363A (en) | New 2-azetidinone derivative | |
JPS55111443A (en) | Preparation of farnesylacetic acid ester | |
JPS57139020A (en) | Preparation of tertiary olefin | |
JPS5770860A (en) | Carboxylic acid derivative and its salt |