JPS57136564A - Preparation of allene derivative - Google Patents

Preparation of allene derivative

Info

Publication number
JPS57136564A
JPS57136564A JP2091781A JP2091781A JPS57136564A JP S57136564 A JPS57136564 A JP S57136564A JP 2091781 A JP2091781 A JP 2091781A JP 2091781 A JP2091781 A JP 2091781A JP S57136564 A JPS57136564 A JP S57136564A
Authority
JP
Japan
Prior art keywords
compound
formula iii
metal
alkyl
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2091781A
Other languages
Japanese (ja)
Inventor
Genichi Dobashi
Shigeko Furukawa
Katsuyuki Ogura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP2091781A priority Critical patent/JPS57136564A/en
Publication of JPS57136564A publication Critical patent/JPS57136564A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare the titled compound useful as a raw material of pharmaceuticals, etc., easily, safely and economically in an industrial scale, by reacting an α-thiocarbonyl compound with a propargyl compound in the presence of a metal carbonate or a metal bicarbonate.
CONSTITUTION: The allene derivative of formulaI(R1 is alkyl, etc.; R2 is H, alkyl, etc.; R3 is H, alkyl, etc.) is prepared by reacting an α-thiocarbonyl compound of formula II with a propargyl compound of formula III (X is halogen or sulfonate group) in the presence of a metal carbonate or a metal bicarbonate (e.g. an alkali metal or an alkaline earth metal salt such as Na2CO3, NaHCO3, etc.). Equivalent amount of the metal salt based on the compound of formula III is sufficient for the purpose; however, larger amount of the salt may be used. The amount of the compound of formula III is equimolar to the compound of formula III. When water is present in the reaction system, the yield can be improved by using ≥1mol, pref. ≥1.3 equivalent of the compound of formula III.
COPYRIGHT: (C)1982,JPO&Japio
JP2091781A 1981-02-17 1981-02-17 Preparation of allene derivative Pending JPS57136564A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2091781A JPS57136564A (en) 1981-02-17 1981-02-17 Preparation of allene derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2091781A JPS57136564A (en) 1981-02-17 1981-02-17 Preparation of allene derivative

Publications (1)

Publication Number Publication Date
JPS57136564A true JPS57136564A (en) 1982-08-23

Family

ID=12040570

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2091781A Pending JPS57136564A (en) 1981-02-17 1981-02-17 Preparation of allene derivative

Country Status (1)

Country Link
JP (1) JPS57136564A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006257006A (en) * 2005-03-16 2006-09-28 Tosoh F-Tech Inc Method for producing allene having fluorine-containing alkyl group

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006257006A (en) * 2005-03-16 2006-09-28 Tosoh F-Tech Inc Method for producing allene having fluorine-containing alkyl group

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