JPS57134465A - Manufacture of 1,5-didesoxy-1,5-imino-d- glucitol or n-derivative thereof - Google Patents

Manufacture of 1,5-didesoxy-1,5-imino-d- glucitol or n-derivative thereof

Info

Publication number
JPS57134465A
JPS57134465A JP56208267A JP20826781A JPS57134465A JP S57134465 A JPS57134465 A JP S57134465A JP 56208267 A JP56208267 A JP 56208267A JP 20826781 A JP20826781 A JP 20826781A JP S57134465 A JPS57134465 A JP S57134465A
Authority
JP
Japan
Prior art keywords
didesoxy
glucitol
imino
derivative
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56208267A
Other languages
English (en)
Other versions
JPH0245624B2 (ja
Inventor
Keberunitsuku Buorufugangu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS57134465A publication Critical patent/JPS57134465A/ja
Publication of JPH0245624B2 publication Critical patent/JPH0245624B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP56208267A 1980-12-30 1981-12-24 Manufacture of 1,5-didesoxy-1,5-imino-d- glucitol or n-derivative thereof Granted JPS57134465A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803049446 DE3049446A1 (de) 1980-12-30 1980-12-30 Verfahren zur herstellung von 1,5-didesoxy-1,5-imino-d-glucitol und dessen n-derivaten

Publications (2)

Publication Number Publication Date
JPS57134465A true JPS57134465A (en) 1982-08-19
JPH0245624B2 JPH0245624B2 (ja) 1990-10-11

Family

ID=6120518

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56208267A Granted JPS57134465A (en) 1980-12-30 1981-12-24 Manufacture of 1,5-didesoxy-1,5-imino-d- glucitol or n-derivative thereof

Country Status (5)

Country Link
US (1) US4611058A (ja)
EP (1) EP0055431B1 (ja)
JP (1) JPS57134465A (ja)
AT (1) ATE7138T1 (ja)
DE (2) DE3049446A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000277A1 (fr) * 1990-06-29 1992-01-09 Nippon Shinyaku Co., Ltd. Derive de piperidine

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3620645A1 (de) * 1985-12-20 1987-07-02 Bayer Ag 3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung
DE3611841A1 (de) * 1986-04-09 1987-10-15 Bayer Ag Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
DE3936295A1 (de) * 1989-11-01 1991-05-02 Bayer Ag Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine
US5013842A (en) * 1990-01-22 1991-05-07 Monsanto Company Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5290948A (en) * 1990-09-17 1994-03-01 Mcneilab, Inc. Process for producing polyhydroxylated piperidines and pyrrolidines and compounds thereof
ATE137266T1 (de) * 1990-09-20 1996-05-15 Monsanto Co Verfahren zur herstellung von n-substituiertem 1- deoxynojirimycin
US5401645A (en) * 1992-03-16 1995-03-28 Monsanto Company Process for producing n-substituted polyhydroxy nitrogen-containing heterocycles utilizing acetobacteraceae and corynebacterium
US20030100532A1 (en) 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
CA2309321A1 (en) 1997-11-10 1999-05-20 G.D. Searle & Co. Use of alkylated iminosugars to treat multidrug resistance
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
AU762125B2 (en) 1998-02-12 2003-06-19 G.D. Searle & Co. Use of (N)-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
AU3595500A (en) 1999-02-12 2000-08-29 G.D. Searle & Co. Use of substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections
WO2001008672A2 (en) 1999-02-12 2001-02-08 G.D. Searle & Co. Glucamine compounds for treating hepatitis virus infections
EP1261339A1 (en) * 2000-02-14 2002-12-04 Pharmacia Corporation Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections
US6462197B2 (en) 2000-03-31 2002-10-08 Board Of Trustees Of Michigan State University Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines
CN1328270C (zh) * 2005-09-26 2007-07-25 鲁南制药集团股份有限公司 一种工业化生产米格列醇的方法
US8097728B2 (en) * 2007-04-30 2012-01-17 Philadelphia Health & Education Corporation Iminosugar compounds with antiflavirus activity
ITUB20150176A1 (it) * 2015-04-17 2016-10-17 Dipharma Francis Srl Sintesi di un azazucchero e i suoi intermedi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2898379A (en) * 1957-06-18 1959-08-04 Callery Chemical Co Reduction of compounds with amine boranes
DE2758025A1 (de) * 1977-12-24 1979-07-12 Bayer Ag Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung
DE2738717A1 (de) * 1977-08-27 1979-03-08 Bayer Ag N-alkylierte derivate der 5-amino- 5-deoxy-d-glucose, verfahren zu ihrer herstellung und ihre verwendung
DE2830469A1 (de) * 1978-07-11 1980-01-24 Bayer Ag Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000277A1 (fr) * 1990-06-29 1992-01-09 Nippon Shinyaku Co., Ltd. Derive de piperidine

Also Published As

Publication number Publication date
DE3163240D1 (en) 1984-05-24
ATE7138T1 (de) 1984-05-15
JPH0245624B2 (ja) 1990-10-11
EP0055431A1 (de) 1982-07-07
EP0055431B1 (de) 1984-04-18
DE3049446A1 (de) 1982-07-29
US4611058A (en) 1986-09-09

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