JPS57108072A - Preparation of n-acylcarnosine - Google Patents
Preparation of n-acylcarnosineInfo
- Publication number
- JPS57108072A JPS57108072A JP55179287A JP17928780A JPS57108072A JP S57108072 A JPS57108072 A JP S57108072A JP 55179287 A JP55179287 A JP 55179287A JP 17928780 A JP17928780 A JP 17928780A JP S57108072 A JPS57108072 A JP S57108072A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- acylaminopropionic
- reactive derivative
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002253 acid Substances 0.000 abstract 4
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000003213 activating effect Effects 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- YVAQHFNMILVVNE-UHFFFAOYSA-N 3-(prop-2-enoylamino)propanoic acid Chemical compound OC(=O)CCNC(=O)C=C YVAQHFNMILVVNE-UHFFFAOYSA-N 0.000 abstract 1
- -1 alkyl chloroformate Chemical compound 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- VFNGKCDDZUSWLR-UHFFFAOYSA-N disulfuric acid Chemical compound OS(=O)(=O)OS(O)(=O)=O VFNGKCDDZUSWLR-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000003715 limbic system Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55179287A JPS57108072A (en) | 1980-12-18 | 1980-12-18 | Preparation of n-acylcarnosine |
US06/329,071 US4387232A (en) | 1980-12-18 | 1981-12-09 | Process for preparing N-acylcarnosine |
CA000392048A CA1167455A (en) | 1980-12-18 | 1981-12-11 | Process for preparing n-acylcarnosine |
DE19813150288 DE3150288A1 (de) | 1980-12-18 | 1981-12-18 | Verfahren zur herstellung von n-acylcarnosin |
FR8123745A FR2496660B1 (fr) | 1980-12-18 | 1981-12-18 | Procede de preparation de n-acylcarnosine |
GB8138218A GB2090831B (en) | 1980-12-18 | 1981-12-18 | A process for preparing n-acylcarnosine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55179287A JPS57108072A (en) | 1980-12-18 | 1980-12-18 | Preparation of n-acylcarnosine |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57108072A true JPS57108072A (en) | 1982-07-05 |
Family
ID=16063186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55179287A Pending JPS57108072A (en) | 1980-12-18 | 1980-12-18 | Preparation of n-acylcarnosine |
Country Status (6)
Country | Link |
---|---|
US (1) | US4387232A (ja) |
JP (1) | JPS57108072A (ja) |
CA (1) | CA1167455A (ja) |
DE (1) | DE3150288A1 (ja) |
FR (1) | FR2496660B1 (ja) |
GB (1) | GB2090831B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58135868A (ja) * | 1982-02-05 | 1983-08-12 | Ajinomoto Co Inc | N−アシルカルノシンの製造法 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2756565B1 (fr) | 1996-12-04 | 1998-12-31 | Oreal | Nouveaux derives d'histidine et leur utilisation en cosmetique ou en pharmacie |
RU2141483C1 (ru) * | 1997-07-04 | 1999-11-20 | Небольсин Владимир Евгеньевич | Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция |
WO2004028536A1 (en) * | 2002-09-30 | 2004-04-08 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
CN101585813B (zh) * | 2009-06-17 | 2011-04-13 | 常熟富士莱医药化工有限公司 | N-乙酰-l-肌肽的制备方法 |
CN105153038B (zh) * | 2014-06-11 | 2017-07-04 | 上海予利化学科技有限公司 | 一种n‑乙酰肌肽的合成方法 |
CN105461632B (zh) * | 2016-01-04 | 2018-01-09 | 湖北泓肽生物科技有限公司 | 一种n‑乙酰‑l‑肌肽的制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52111572A (en) * | 1976-03-16 | 1977-09-19 | Santen Pharmaceutical Co Ltd | Nn*mercapto substituted acyl**hystidine |
-
1980
- 1980-12-18 JP JP55179287A patent/JPS57108072A/ja active Pending
-
1981
- 1981-12-09 US US06/329,071 patent/US4387232A/en not_active Expired - Lifetime
- 1981-12-11 CA CA000392048A patent/CA1167455A/en not_active Expired
- 1981-12-18 FR FR8123745A patent/FR2496660B1/fr not_active Expired
- 1981-12-18 GB GB8138218A patent/GB2090831B/en not_active Expired
- 1981-12-18 DE DE19813150288 patent/DE3150288A1/de active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52111572A (en) * | 1976-03-16 | 1977-09-19 | Santen Pharmaceutical Co Ltd | Nn*mercapto substituted acyl**hystidine |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58135868A (ja) * | 1982-02-05 | 1983-08-12 | Ajinomoto Co Inc | N−アシルカルノシンの製造法 |
Also Published As
Publication number | Publication date |
---|---|
GB2090831A (en) | 1982-07-21 |
DE3150288A1 (de) | 1982-08-26 |
FR2496660A1 (fr) | 1982-06-25 |
GB2090831B (en) | 1985-04-24 |
FR2496660B1 (fr) | 1985-11-22 |
US4387232A (en) | 1983-06-07 |
CA1167455A (en) | 1984-05-15 |
DE3150288C2 (ja) | 1990-07-05 |
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